{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,19]],"date-time":"2026-06-19T16:52:05Z","timestamp":1781887925669,"version":"3.54.5"},"reference-count":15,"publisher":"S. Karger AG","issue":"1","license":[{"start":{"date-parts":[[2026,4,24]],"date-time":"2026-04-24T00:00:00Z","timestamp":1776988800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,4,24]],"date-time":"2026-04-24T00:00:00Z","timestamp":1776988800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Rep Oncol"],"abstract":"<jats:p>Introduction: Carriers of Duchenne muscular dystrophy (DMD) and other inherited myopathies are at risk of cardiomyopathy, and HER2-targeted therapies for breast cancer are also associated with cardiotoxicity. The coexistence of these conditions presents a novel clinical challenge. Standard baseline cardiac evaluations prior to HER2-targeted therapy do not routinely detect inherited cardiomyopathies, and genetic risk is not currently incorporated into pretreatment assessment. Case Report: We report the case of a woman in her 30s with HER2-positive breast cancer with baseline borderline low global longitudinal strain who was incidentally identified as a carrier of a DMD gene mutation after her son was diagnosed with DMD and developed an asymptomatic decline in left ventricular ejection fraction during treatment. Conclusion: This case highlights the potential role of increased cardiac surveillance and consideration of cardioprotective medications and genetic screening in patients with baseline abnormal echocardiograms prior to receiving cardiotoxic cancer therapies.<\/jats:p>","DOI":"10.1159\/000552006","type":"journal-article","created":{"date-parts":[[2026,4,24]],"date-time":"2026-04-24T16:00:51Z","timestamp":1777046451000},"page":"738-742","source":"Crossref","is-referenced-by-count":0,"title":["Potential Influence of Duchenne Muscular Dystrophy Carrier on Breast Cancer Treatment-Related Cardiomyopathy: A Case Report"],"prefix":"10.1159","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-1876-3776","authenticated-orcid":false,"given":"Shivali","family":"Desai","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick","family":"Dillon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2026,4,24]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.3390\/cancers13174287"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.3390\/jcm13010002"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1038\/s41536-022-00214-x"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.2217\/bmm-2018-0125"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1186\/1750-1172-7-82"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.4070\/kcj.2021.0154"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1007\/s10549-021-06096-9"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.3390\/jcm9061702"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1007\/s13402-020-00572-y"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1161\/circulationaha.113.006891"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1016\/j.cardfail.2018.03.004"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1186\/s40959-024-00220-6"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaccao.2020.08.010"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1007\/s10549-014-3253-7"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1007\/s10549-019-05191-2"}],"container-title":["Case Reports in Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/karger.com\/article-pdf\/doi\/10.1159\/000552006","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,19]],"date-time":"2026-06-19T16:00:54Z","timestamp":1781884854000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000552006"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4,24]]},"references-count":15,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026,1,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000552006","archive":["Portico"],"relation":{"is-supplemented-by":[{"id-type":"doi","id":"10.6084\/m9.figshare.32021217","asserted-by":"subject"}]},"ISSN":["1662-6575"],"issn-type":[{"value":"1662-6575","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4,24]]}}}