{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T16:50:38Z","timestamp":1782233438268,"version":"3.54.5"},"reference-count":28,"publisher":"S. Karger AG","license":[{"start":{"date-parts":[[2026,4,24]],"date-time":"2026-04-24T00:00:00Z","timestamp":1776988800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"},{"start":{"date-parts":[[2026,4,24]],"date-time":"2026-04-24T00:00:00Z","timestamp":1776988800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Skin Appendage Disord"],"abstract":"<jats:p>Introduction: Alopecia areata (AA) has a major psychological impact, yet Brazilian data on patients\u2019 and caregiver\u2019s quality of life (QoL) are lacking. We aimed to assess QoL in patients with AA and their caregivers and identify clinical and socioeconomic correlates. Methods: A cross-sectional study including 118 patients (83 adults, 35 children\/adolescents) aged \u22654 years with active scalp AA and 58 caregivers was performed at a tertiary dermatology center (2022-2024). QoL was evaluated with DLQI, CDLQI, and FDLQI. Disease severity was scored with Severity of Alopecia Tool (SALT) II. Sociodemographic and clinical data were analyzed using parametric and nonparametric tests (p \u2264 0.05). Results: Participants were predominantly female (63.6%) and of mixed race (53.5%), with mean age of 27.6 years. Mean SALT II was 33.9%. Multifocal (39.3%) AA predominated. QoL impact was moderate in adults (median DLQI 6; IQR 3\u201310) and mild in youth (median CDLQ 5; IQR 2\u20138) but greater among caregivers (median FDLQI 9; IQR 6\u201314). Patient-caregivers QoL scores correlated positively (Rho = 0.48, p &lt; 0.001). Dermatologic comorbidities worsened QoL in both groups. Conclusion: AA exerts substantial psychosocial burden on whole family. Caregivers experience higher impairment than patients, underscoring the need for family-centered interventions in Latin America.<\/jats:p>","DOI":"10.1159\/000552060","type":"journal-article","created":{"date-parts":[[2026,4,24]],"date-time":"2026-04-24T16:01:04Z","timestamp":1777046464000},"page":"1-8","source":"Crossref","is-referenced-by-count":0,"title":["Quality of Life in Brazilian Patients with Alopecia Areata and Their Caregivers"],"prefix":"10.1159","author":[{"given":"Isabela Peron","family":"Melhado","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2910-7330","authenticated-orcid":false,"given":"Maria Cec\u00edlia","family":"Rivitti-Machado","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1124-7175","authenticated-orcid":false,"given":"Isabella","family":"Doche","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2026,4,24]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2018.12.051"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016\/j.abd.2022.11.001"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1007\/s13555-022-00845-4"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2016.08.042"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016\/j.abd.2025.501146"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1038\/jid.2010.232"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.2012.04629.x"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2018.01.048"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2021.08.043"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1097\/00004583-199611000-00021"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1097\/00004583-199705000-00019"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1159\/000497166"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1038\/jidsymp.2013.18"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1080\/13548506.2014.894641"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.14497"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.13520"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2016.04.035"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.5021\/ad.21.202"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1111\/ijd.17154"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.18926"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1007\/s13555-023-00941-z"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1016\/j.jid.2022.02.019"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1111\/j.0022-202x.2005.23970.x"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph192316323"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2020.06.047"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1155\/2014\/304370"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1016\/j.clindermatol.2018.08.011"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.1111\/dth.12255"}],"container-title":["Skin Appendage Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/karger.com\/article-pdf\/doi\/10.1159\/000552060","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T16:08:16Z","timestamp":1782230896000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000552060"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4,24]]},"references-count":28,"URL":"https:\/\/doi.org\/10.1159\/000552060","archive":["Portico"],"relation":{},"ISSN":["2296-9195","2296-9160"],"issn-type":[{"value":"2296-9195","type":"print"},{"value":"2296-9160","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4,24]]}}}