{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T16:09:03Z","timestamp":1784218143485,"version":"3.55.0"},"reference-count":26,"publisher":"S. Karger AG","issue":"4","license":[{"start":{"date-parts":[[2026,4,27]],"date-time":"2026-04-27T00:00:00Z","timestamp":1777248000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"},{"start":{"date-parts":[[2026,4,27]],"date-time":"2026-04-27T00:00:00Z","timestamp":1777248000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Audiol Neurotol"],"abstract":"<jats:p>Introduction: This study differentiates cases of acute-onset sensorineural hearing loss (SNHL) that did not meet the diagnostic criteria for either sudden SNHL or Meniere\u2019s disease, leading to a diagnostic challenge. Methods: All 46 patients with acute-onset SNHL underwent an inner ear test battery followed by hydrops magnetic resonance imaging (MRI). Twenty-four patients (28 ears) who tested positive for endolymphatic hydrops (EH) on hydrops MRI were referred to the EH group. Another 22 patients (22 ears) who tested negative for EH were classified as the non-EH group. Results: Significant difference in the mean hearing levels between EH and non-EH groups was identified at frequencies of 125, 250, 500, and 1,000 Hz, but not at frequencies ranging from 2,000 Hz through 8,000 Hz. A declining sequence of abnormality rates \u2013 from audiometry (96%), cervical vestibular-evoked myogenic potential (cVEMP) test (75%), ocular VEMP test (57%) to the caloric test (43%) \u2013 was observed in the EH group but not in the non-EH group. This pattern closely paralleled the decreasing prevalence of EH on hydrops MRI, which moved from the cochlea (79%), saccule (61%), utricle (57%) to the semicircular canals (4%). Conclusion: A comprehensive inner ear test battery aligned with hydrops MRI may enhance understanding of disease mechanisms and aid differential diagnosis in selected ambiguous cases of acute-onset SNHL, whether it arises from EH.<\/jats:p>","DOI":"10.1159\/000552081","type":"journal-article","created":{"date-parts":[[2026,4,27]],"date-time":"2026-04-27T16:01:06Z","timestamp":1777305666000},"page":"299-306","source":"Crossref","is-referenced-by-count":0,"title":["Inner Ear Test Battery Aligned with Hydrops Magnetic Resonance Imaging to Differentiate Acute-Onset Sensorineural Hearing Loss"],"prefix":"10.1159","volume":"31","author":[{"given":"Jui-En","family":"Lee","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu-Fen","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3194-5811","authenticated-orcid":false,"given":"Yi-Ho","family":"Young","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2026,4,27]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1980.00790360050013"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1038\/nrdp.2016.28"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-197109000-00010"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1097\/MOO.0b013e3282ef772d"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.3109\/00016486709139139"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1080\/00016489.2021.1934537"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0000000000001036"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1177\/0194599812436449"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1016\/s0194-5998(95)70102-8"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.3233\/VES-150549"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1080\/00016480510012363"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.2463\/mrms.2012-0027"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1177\/19160216241250350"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-196007000-00002"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1002\/lary.23640"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.3174\/ajnr.A3856"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1007\/s00234-019-02155-7"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1159\/000312199"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1177\/000348949210100713"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1002\/lary.25922"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1080\/14992027.2022.2075799"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1177\/000348948709600418"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1002\/lio2.869"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1016\/j.jfma.2021.08.027"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1080\/00016489.2018.1498594"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1159\/000275597"}],"container-title":["Audiology and Neurotology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/karger.com\/article-pdf\/doi\/10.1159\/000552081","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T16:01:21Z","timestamp":1784217681000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000552081"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4,27]]},"references-count":26,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2026,7,16]]},"published-print":{"date-parts":[[2026,8,5]]}},"URL":"https:\/\/doi.org\/10.1159\/000552081","archive":["Portico"],"relation":{},"ISSN":["1420-3030","1421-9700"],"issn-type":[{"value":"1420-3030","type":"print"},{"value":"1421-9700","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4,27]]}}}