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This narrative review summarizes emerging innovations across plasma, red blood cells (RBCs), platelets, donor stem cells, and cord blood. Summary: Developments in plasma technology, including dried plasma, isoagglutinin-depleted universal plasma, and protein-derived products aim to enhance safety, stability, and clinical applicability. RBC innovations focus on improved preservation, engineered or artificial oxygen carriers, extracellular vesicle-based products, and strategies for producing universal blood cells. Platelet-derived products such as platelet-rich plasma, platelet lysates, and platelet extracellular vesicles are expanding applications beyond hemostasis into regenerative medicine. Advances in donor stem cell technologies offer new pathways for scalable, donor-independent production of blood cells. Additionally, cord blood (CB)-derived red cells represent a promising new product with unique biological properties. 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