{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T19:40:16Z","timestamp":1791229216333,"version":"4.1.0"},"reference-count":27,"publisher":"S. Karger AG","license":[{"start":{"date-parts":[[2026,5,28]],"date-time":"2026-05-28T00:00:00Z","timestamp":1779926400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,5,28]],"date-time":"2026-05-28T00:00:00Z","timestamp":1779926400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Blood Purif"],"abstract":"<jats:p>Introduction: Accurate volume assessment during the immediate post-kidney transplantation period reduces morbidity and mortality. Lung ultrasound (LUS), venous excess ultrasound score (VExUS), and bioimpedance analysis (BIA) are emerging methods for volume evaluation. We hypothesise LUS+VExUS may provide accurate means of congestion assessment in renal transplant patients, allowing more precise care. Method: An exploratory, prospective, single-centre pilot study was conducted. A prospective cohort (Group 1, n = 31) underwent volume assessment using a combined VExUS + LUS protocol on days +1 and +7 post-transplantation, alongside physical examination (PhE) and BIA. Findings were compared with a historical reference cohort (Group 2, n = 40) managed with standard clinical assessment alone. Results: Groups differed significantly in delayed graft function (45.2% vs. 15.0%, p = 0.008) and cold ischaemia time (p = 0.027). Acute pulmonary oedema occurred in 2\/31 patients (6.5%) in Group 1 and 6\/40 (15.0%) in Group 2, though this difference was not statistically significant (Fisher exact p = 0.452). VExUS showed no correlation with BIA (Spearman \u03c1 = 0.127, p = 0.545), BNP (\u03c1 = 0.187, p = 0.349), or Ca125 (\u03c1 = 0.241, p = 0.226). VExUS detected venous congestion (grade \u22651) in 2\/14 patients (14.3%) with normal PhE on Day +1. PhE showed poor agreement with VExUS (\u03ba = 0.043) and moderate agreement with LUS (\u03ba = 0.469). Combined ultrasound identified subclinical congestion in 28.6% of patients with normal PhE. Ultrasound findings prompted therapeutic modifications in 74.2% of cases on Day +1 (primarily IV fluid reduction) and 16.1% on Day +7. Conclusion: In this exploratory pilot study, VExUS and LUS provided additional diagnostic information beyond PhE and influenced clinical decision-making in the majority of cases. These hypothesis-generating findings warrant confirmation in larger, multicentre, prospective studies with standardised protocols.<\/jats:p>","DOI":"10.1159\/000552658","type":"journal-article","created":{"date-parts":[[2026,5,28]],"date-time":"2026-05-28T16:01:46Z","timestamp":1779984106000},"page":"1-12","source":"Crossref","is-referenced-by-count":2,"title":["Point-of-Care Ultrasound in Post-Kidney Transplant Patients: Venous Excess Ultrasound Score and Lung Ultrasound for Fluid Assessment"],"prefix":"10.1159","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3292-0819","authenticated-orcid":false,"given":"R. Haridian","family":"Sosa Barrios","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Irene","family":"M\u00ednguez Toral","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V\u00edctor M.","family":"Burguera Vion","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cristina","family":"Galeano \u00c1lvarez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandra","family":"El\u00edas Trivi\u00f1o","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Milagros","family":"Fern\u00e1ndez Lucas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maite E.","family":"Rivera Gorr\u00edn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2026,5,28]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1097\/MNH.0000000000000409"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.2215\/CJN.0000000000000552"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccl.2020.01.004"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.24908\/pocusj.v10i01.18260"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-200401000-00006"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1186\/s13089-021-00232-8"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016\/j.jchf.2016.03.016"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.118.009961"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.3904\/kjim.2017.313"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1159\/000457897"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.2215\/CJN.03890416"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1053\/j.ackd.2021.03.004"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfn707"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.108.807362"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.3389\/fcvm.2022.772466"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.3904\/kjim.2017.355"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0158765"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2008.08.080"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1378\/chest.127.5.1690"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2023.06.003"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1136\/thx.2009.128496"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.34067\/KID.0006482020"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.4300\/JGME-D-20-00216.1"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1186\/s13089-020-00163-w"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1016\/j.cardfail.2007.07.003"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-005-0024-2"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1016\/j.transproceed.2018.03.007"}],"container-title":["Blood Purification"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/karger.com\/article-pdf\/doi\/10.1159\/000552658","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,21]],"date-time":"2026-07-21T16:01:05Z","timestamp":1784649665000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000552658"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5,28]]},"references-count":27,"URL":"https:\/\/doi.org\/10.1159\/000552658","archive":["Portico"],"relation":{"is-supplemented-by":[{"id-type":"doi","id":"10.6084\/m9.figshare.32403900","asserted-by":"subject"}]},"ISSN":["0253-5068","1421-9735"],"issn-type":[{"value":"0253-5068","type":"print"},{"value":"1421-9735","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,5,28]]}}}