{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,11]],"date-time":"2026-08-11T16:50:27Z","timestamp":1786467027978,"version":"build-2736575974"},"reference-count":8,"publisher":"S. Karger AG","issue":"1","license":[{"start":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T00:00:00Z","timestamp":1783555200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T00:00:00Z","timestamp":1783555200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Glomerular Dis"],"abstract":"<jats:p>Introduction: Primary membranous nephropathy, one of the most common primary nephrotic syndromes in adults, rarely has tubular involvement. Two case reports have previously illustrated atypical tubular manifestations, including Liddle-like syndrome and proximal tubulopathy. Hypokalemic distal tubulopathy in anti-phospholipase A2 receptor antibody-positive membranous nephropathy has not yet been recognized. Case Presentation: We report a case of a 37-year-old Thai male presenting with nephrotic syndrome and rhabdomyolysis secondary to severe hypokalemia. Kidney biopsy and serologic testing confirmed anti-phospholipase A2 receptor antibody-positive membranous nephropathy. Urinary indices showed a distal tubulopathy pattern. Hormonal studies, including plasma renin, plasma aldosterone, and a dexamethasone suppression test, were all negative. The patient responded well to prednisolone and oral cyclophosphamide. With nephrotic syndrome remission, hypokalemia was alleviated simultaneously. Conclusion: This case suggests a recognition and expansion of the knowledge of an extremely rare tubular involvement in relation to anti-phospholipase A2 receptor antibody-positive membranous nephropathy.<\/jats:p>","DOI":"10.1159\/000553335","type":"journal-article","created":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T16:00:56Z","timestamp":1783612856000},"page":"285-290","source":"Crossref","is-referenced-by-count":0,"title":["Hypokalemic Distal Tubulopathy Secondary to Anti-Phospholipase A2 Receptor-Positive Membranous Nephropathy: An Exceptional Case"],"prefix":"10.1159","volume":"6","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1007-907X","authenticated-orcid":false,"given":"Thanawat","family":"Vongchaiudomchoke","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7069-7128","authenticated-orcid":false,"given":"Boonyarit","family":"Cheunsuchon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1623-3071","authenticated-orcid":false,"given":"Nuttaya","family":"Wachiraphansakul","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2026,7,9]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.2215\/CJN.11761116"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1038\/s41572-021-00303-z"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1186\/s12882-018-0916-3"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1186\/s12882-023-03130-4"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016\/j.cca.2019.01.015"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2020071082"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfad227"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2025.01.014"}],"container-title":["Glomerular Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/karger.com\/article-pdf\/doi\/10.1159\/000553335","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,11]],"date-time":"2026-08-11T16:00:58Z","timestamp":1786464058000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000553335"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7,9]]},"references-count":8,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026,1,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000553335","archive":["Portico"],"relation":{"is-supplemented-by":[{"id-type":"doi","id":"10.6084\/m9.figshare.32923106","asserted-by":"subject"}]},"ISSN":["2673-3633"],"issn-type":[{"value":"2673-3633","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,7,9]]}}}