{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T16:51:08Z","timestamp":1787071868588,"version":"build-2736575974"},"reference-count":27,"publisher":"S. Karger AG","license":[{"start":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T00:00:00Z","timestamp":1783641600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"},{"start":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T00:00:00Z","timestamp":1783641600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Horm Res Paediatr"],"abstract":"<jats:p>Introduction: Calcium-sensing receptor (CaSR) variants are a rare cause of congenital hypoparathyroidism. Current standard treatment consists of calcitriol and calcium supplements, but this regimen increases the risk of kidney complications due to hypercalciuria. Case Presentation: Here, we present the case of a toddler with an activating CaSR mutation and severe complications of calcium and calcitriol treatment, who exhibited significant clinical improvement after initiation of teriparatide, an injectable parathyroid hormone analog. Conclusion: Studies of teriparatide use in children have shown that it is well tolerated and efficacious for the long-term management of hypoparathyroidism. 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