{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T16:23:20Z","timestamp":1787675000415,"version":"build-2784847793"},"reference-count":18,"publisher":"S. Karger AG","license":[{"start":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T00:00:00Z","timestamp":1784160000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T00:00:00Z","timestamp":1784160000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neuroepidemiology"],"abstract":"<jats:p>Introduction: Migraine is a common neurological disorder with attacks lasting 4\u201372 h. Although duration is a key diagnostic criterion, the clinical and demographic factors associated with its variability are not well defined. Identifying temporal phenotypes may improve diagnostic accuracy and inform individualized management. Methods: In this cross-sectional observational study, we evaluated 694 patients fulfilling ICHD-3 migraine criteria. Patients were categorized by attack duration into short (4\u201312 h), medium (13\u201324 h), and long (&gt;24 h) groups. Sociodemographic features, migraine characteristics, associated symptoms, and disability measures were compared across groups. Multinomial logistic regression was performed using the short-duration group as the reference category to identify variables independently associated with medium- and long-duration attacks. Results: Of 694 participants (84% female; mean age 36.66 \u00b1 12.20 years), 33.3% (n = 231) experienced short, 28.2% (n = 196) medium, and 38.5% (n = 267) long attacks. Long-duration attacks were associated with older age (39.98 \u00b1 11.36 vs. 34.09 \u00b1 12.62 years, p &lt; 0.001), higher female ratio (89.1% vs. 78.8%, p = 0.007), and lower educational level (p = 0.008). Patients with prolonged attacks had higher allodynia scores (median ASC 6 vs. 4, p &lt; 0.001), greater pain intensity (VAS 9 vs. 8, p &lt; 0.001), and more frequent nausea and vomiting (p = 0.002). Illness duration was the longest in the long-attack group (median 120 vs. 60 months, p &lt; 0.001). Other clinical characteristics, including aura, localization, and chronic migraine rates, showed no significant differences. In multivariable analysis, older age and higher pain intensity remained independently associated with long-duration attacks, while lower educational level and higher pain intensity were independently associated with medium-duration attacks. Conclusion: Migraine attack duration is associated with distinct demographic and clinical characteristics independent of attack frequency. In multivariable analysis, older age and higher pain intensity remained independently associated with long-duration attacks, while lower educational level and higher pain intensity were independently associated with medium-duration attacks. These findings suggest that attack duration could represent a meaningful clinical phenotype; therefore, frequency-based classification approaches might overlook patients with infrequent but prolonged and disabling attacks.<\/jats:p>","DOI":"10.1159\/000553571","type":"journal-article","created":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T16:01:13Z","timestamp":1784217673000},"page":"1-7","source":"Crossref","is-referenced-by-count":0,"title":["Factors Associated with Migraine Attack Duration in Adults: A Cross-Sectional Study"],"prefix":"10.1159","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0142-8290","authenticated-orcid":false,"given":"Tu\u011fba","family":"Okluo\u011flu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-7186-944X","authenticated-orcid":false,"given":"Beng\u00fcl Fatma","family":"G\u00f6lge","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mehmet Ali","family":"Sungur","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Osman \u00d6zg\u00fcr","family":"Yal\u0131n","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2026,7,16]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra010917"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1468-2982.2003.00568.x"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-2982.2006.01075.x"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1111\/head.14488"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000252808.97649.21"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-2982.2003.00824.x"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000133301.66364.9b"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1177\/0333102417738202"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-2982.2007.01279.x"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1186\/s10194-021-01362-z"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1186\/s10194-023-01546-9"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-2982.2004.00621.x"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1016\/s0733-8619(05)70299-1"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1177\/0333102414552532"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1017\/S1463423619000720"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1007\/s11682-022-00690-1"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.0373-15.2015"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1002\/wjo2.70069"}],"container-title":["Neuroepidemiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/karger.com\/article-pdf\/doi\/10.1159\/000553571","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T16:00:38Z","timestamp":1787673638000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000553571"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7,16]]},"references-count":18,"URL":"https:\/\/doi.org\/10.1159\/000553571","archive":["Portico"],"relation":{"is-supplemented-by":[{"id-type":"doi","id":"10.6084\/m9.figshare.33006182","asserted-by":"subject"}]},"ISSN":["0251-5350","1423-0208"],"issn-type":[{"value":"0251-5350","type":"print"},{"value":"1423-0208","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,7,16]]}}}