{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T07:54:34Z","timestamp":1790927674987,"version":"4.1.0"},"reference-count":0,"publisher":"S. Karger AG","license":[{"start":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T00:00:00Z","timestamp":1790726400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T00:00:00Z","timestamp":1790726400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Psychother Psychosom"],"abstract":"<jats:p>Introduction: Physical exercise administered before or after exposure has been shown to have beneficial effects on treatment outcomes in anxiety- and trauma-related disor-ders. However, this approach has not yet been examined for obsessive\u2013compulsive dis-order (OCD). This randomized controlled trial investigated whether high-intensity exer-cise administered immediately after exposure therapy improves treatment outcomes in patients with obsessive-compulsive disorder (OCD). Methods: Ninety-seven inpatients with OCD participated in an eight-week exposure-based treatment phase during inpa-tient care, comprising two sessions per week, and were randomly assigned to either high-intensity exercise (ExpoHI) or low-intensity control (ExpoLI) administered immedi-ately after a standardized exposure and response prevention (ERP) session. OCD se-verity was assessed using the Yale\u2013Brown Obsessive Compulsive Scale (Y-BOCS) at admission, discharge, and six-month follow-up. The secondary outcomes included gen-eral psychopathological symptoms. Results: ExpoHI showed significantly greater reduc-tions in Y-BOCS scores at discharge (between-group difference: \u22123.14 points, p = .009), corresponding to a moderate-to-large between-group effect size (Cohen\u2019s d = 0.76), which was maintained at the six-month follow-up (p = .030; Cohen\u2019s d = 0.68). Re-sponder rates at discharge were significantly higher in the ExpoHI group (85.4%) than in the ExpoLI group (61.2%) (p = .011), whereas remission rates did not differ between groups. ExpoHI also showed greater reductions in depressive symptoms at follow-up. Conclusions: High-intensity exercise immediately following exposure therapy produced greater reductions in obsessive\u2013compulsive symptoms than the active control condition. These findings suggest that exercise may be a feasible adjunct for exposure-based treatment.<\/jats:p>","DOI":"10.1159\/pps\/aemag016","type":"journal-article","created":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T19:14:37Z","timestamp":1789672477000},"source":"Crossref","is-referenced-by-count":0,"title":["Does high-intensity exercise combined with exposure sessions improve treatment out-comes in obsessive-compulsive disorder? A randomized controlled trial in inpatients"],"prefix":"10.1159","author":[{"given":"Mark","family":"Muehlbacher","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rebecca","family":"Schennach","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Boesl","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christoph","family":"Bamberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefan","family":"Koch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ulrich","family":"Voderholzer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2026,9,30]]},"container-title":["Psychotherapy and Psychosomatics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/karger.com\/article-pdf\/doi\/10.1159\/pps\/aemag016","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T07:18:28Z","timestamp":1790925508000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/pps\/aemag016"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,30]]},"references-count":0,"URL":"https:\/\/doi.org\/10.1159\/pps\/aemag016","archive":["Portico"],"relation":{"is-supplemented-by":[{"id-type":"doi","id":"10.6084\/m9.figshare.33981577","asserted-by":"subject"}]},"ISSN":["0033-3190","1423-0348"],"issn-type":[{"value":"0033-3190","type":"print"},{"value":"1423-0348","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,30]]}}}