{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T16:46:31Z","timestamp":1791996391870,"version":"4.4.0"},"reference-count":24,"publisher":"S. Karger AG","license":[{"start":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T00:00:00Z","timestamp":1791590400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T00:00:00Z","timestamp":1791590400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Transfus Med Hemother"],"abstract":"<jats:p>Introduction: In Switzerland, platelet (PLT) donation is allowed with hemoglobin (Hb) \u2265110 g\/L and \u2265120 g\/L for women and men, respectively. We report on a policy of proposing PLT apheresis to female donors no longer eligible for whole blood (WB) donation because of low Hb and\/or iron deficiency. Methods: We assessed 85 women with Hb &lt;125 g\/L and\/or ferritin \u2264 15 \u00b5g\/L who changed to PLT apheresis between 01\/1997 and 12\/2023 and underwent at least one PLT apheresis\/year. Hb and ferritin were evaluated at the first WB donation, at the first and last PLT apheresis and were estimated as adjusted values over 30 PLT donations. Donor retention over a 24-month period was evaluated. Results: The switch to PLT apheresis occurred after a median of 3 (range: 1\u201333) WB donations. In 42 women (49%), both Hb and ferritin were low, 32 (38%) had low ferritin, and 11 (13%) low Hb only, respectively. Median age (range) at first WB donation and at last PLT donation was 30 years (18\u201353 years) and 45 years (19\u201368 years), respectively. Median (range) Hb and ferritin were 134 g\/L (120\u2013153 g\/L) and 24 \u00b5g\/L (2\u2013177 \u00b5g\/L) at the first WB donation and 130 g\/L (103\u2013154 g\/L) and 14.5 \u00b5g\/L (3\u2013113 \u00b5g\/L) at the last PLT apheresis. Over the course of 30 PLT donations and adjusted for donor age, an increasing trend was observed for both Hb (mean + 0.26 g\/L; 95% CI: 0.16, 0.35; p &lt; 0.001) and ferritin (mean + 0.48 \u00b5g\/L; 95% CI: 0.21, 0.75; p &lt; 0.001). At the end of a 24-month period, 94% (95% CI: 86.4%, 97.5%) women were still donating. Conclusion: Women with low Hb and\/or iron deficiency benefit from a change to PLT donation and can be retained as regular, highly committed PLT donors.<\/jats:p>","DOI":"10.1159\/tmh\/aevag005","type":"journal-article","created":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T11:40:07Z","timestamp":1790077207000},"page":"1-1","source":"Crossref","is-referenced-by-count":0,"title":["Platelet Donation by Apheresis for Female Blood Donors with Low Hemoglobin or Iron Deficiency"],"prefix":"10.1159","author":[{"given":"Laura","family":"Infanti","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vildana","family":"Pehlic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Volken","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gregor","family":"Stehle","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas","family":"Holbro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas","family":"Buser","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2026,10,10]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1111\/trf.16688"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1111\/trf.14074"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2020-1318"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(24)01212-1"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(24)01085-7"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1111\/trf.13152"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1111\/trf.13469"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1111\/vox.12431"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1016\/S2352-3026(25)00167-X"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1016\/j.transci.2023.103668"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1111\/trf.15729"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3148.2009.00979.x"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1111\/vox.13525"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1111\/vox.13720"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1016\/j.transci.2022.103522"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1046\/j.1537-2995.1998.38998409006.x"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1016\/j.transci.2006.10.006"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1111\/j.1537-2995.2012.03584.x"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1111\/trf.15906"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1111\/trf.17484"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1016\/S2352-3026(21)00168-X"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1182\/bloodadvances.2022007066"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1111\/trf.14272"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1016\/j.tracli.2023.02.006"}],"container-title":["Transfusion Medicine and Hemotherapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/karger.com\/article-pdf\/doi\/10.1159\/tmh\/aevag005","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T16:03:44Z","timestamp":1791993824000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/tmh\/aevag005"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10,10]]},"references-count":24,"URL":"https:\/\/doi.org\/10.1159\/tmh\/aevag005","archive":["Portico"],"relation":{},"ISSN":["1660-3796","1660-3818"],"issn-type":[{"value":"1660-3796","type":"print"},{"value":"1660-3818","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,10,10]]}}}