{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T23:01:31Z","timestamp":1777762891483,"version":"3.51.4"},"reference-count":0,"publisher":"S. Karger AG","license":[{"start":{"date-parts":[[2008,5,2]],"date-time":"2008-05-02T00:00:00Z","timestamp":1209686400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"},{"start":{"date-parts":[[2008,5,2]],"date-time":"2008-05-02T00:00:00Z","timestamp":1209686400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cytogenet Cell Genet"],"abstract":"<jats:p>A human-mouse hybrid, DUR 4 (Solomon et al., 1976), containing a human X\/15 translocation chromosome and also chromosome 5, among other human chromosomes, was used in a double selection system to obtain hybrids of four different types: X\/15+ 5+, X\/15\u2013 5+, X\/15+ 5, and X\/15\u2013 5\u2013. Standard positive and negative selection systems were used for the X chromosome, and negative selection for chromosome 5 was done with diphtheria toxin. The assignment of HEX&lt;sub&gt;B&lt;\/sub&gt; and the diphtheria toxin sensitivity gene to chromosome 5 was confirmed. HEX&lt;sub&gt;A&lt;\/sub&gt; was present only when both the X\/15 chromosome and chromosome 5 were present. A \u201cHEX&lt;sub&gt;A&lt;\/sub&gt;-like\u201d band segregated with chromosome 15 (or X\/15) but independently of chromosome 5. This component, unlike HEX&lt;sub&gt;A&lt;\/sub&gt;, does not contain human HEX&lt;sub&gt;\u03b2&lt;\/sub&gt; antigen.<\/jats:p>","DOI":"10.1159\/000130758","type":"journal-article","created":{"date-parts":[[2008,5,6]],"date-time":"2008-05-06T10:30:07Z","timestamp":1210069807000},"page":"136-148","source":"Crossref","is-referenced-by-count":45,"title":["Immunochemical analysis of the N-acetyl hexosaminidases in human-mouse hybrids made using a double selective system"],"prefix":"10.1159","author":[{"given":"D.M.","family":"Swallow","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Solomon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.","family":"Pajunen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2008,5,2]]},"container-title":["Cytogenetics and Cell Genetics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/130758","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/karger.com\/article-pdf\/doi\/10.1159\/000130758","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T14:36:58Z","timestamp":1777473418000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000130758"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,5,2]]},"references-count":0,"URL":"https:\/\/doi.org\/10.1159\/000130758","archive":["Portico"],"relation":{},"ISSN":["0301-0171","1421-9816"],"issn-type":[{"value":"0301-0171","type":"print"},{"value":"1421-9816","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,5,2]]}}}