{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,3]],"date-time":"2026-03-03T16:41:52Z","timestamp":1772556112032,"version":"3.50.1"},"reference-count":32,"publisher":"S. Karger AG","issue":"1","license":[{"start":{"date-parts":[[2008,11,26]],"date-time":"2008-11-26T00:00:00Z","timestamp":1227657600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2008,11,26]],"date-time":"2008-11-26T00:00:00Z","timestamp":1227657600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int Arch Allergy Immunol"],"published-print":{"date-parts":[[2009]]},"abstract":"<i>Background:<\/i> Peach is a common food allergen source throughout Europe. The aim of this study was to characterize peach allergy in a Portuguese patient population. <i>Methods:<\/i> Thirty peach-allergic patients confirmed by double-blind placebo-controlled food challenges and 29 controls were included. All subjects completed a standardized questionnaire regarding symptoms and epidemiologic characteristics, skin prick tests with inhalant allergens and foods as well as specific IgE antibodies to peach, recombinant peach allergens rPru p 1, rPru p 3, rPru p 4 and cross-reactive carbohydrate determinants. <i>Results:<\/i> Thirty-seven percent of patients reported only oral allergy syndrome, while 37% reported generalized urticaria and\/or angioedema, 17% localized contact urticaria and 10% anaphylaxis with peach. Sensitization to other <i>Rosaceae<\/i> fruits and tree nuts was present in 90 and 77% of the patients, respectively. Respiratory allergy history was associated with less severe symptoms (oral allergy syndrome or contact urticaria; p < 0.01) and positive skin prick test to peach peel or plum with more severe symptoms (urticaria and\/or angioedema or anaphylaxis; p < 0.05). Ninety-seven percent were sensitized to Pru p 3, 13% to Pru p 4, 3% to Pru p 1 and 10% to cross-reactive carbohydrate determinants. Pru p 3 specific IgE was associated with <i>Artemisia vulgaris<\/i> sensitization and tree nut allergy (p < 0.05) but not with clinical severity. <i>Conclusions:<\/i> Half the patients reported systemic reactions to peach. Peach allergy appeared predominantly mediated by Pru p 3 but some patients were sensitized to Pru p 4. Applying a 0.10 kU<sub>A<\/sub>\/l cutoff level, the diagnostic value of combining the 3 recombinant allergens was noteworthy, with 100% sensitivity and 90% specificity.<\/jats:p>","DOI":"10.1159\/000176308","type":"journal-article","created":{"date-parts":[[2008,11,29]],"date-time":"2008-11-29T14:18:13Z","timestamp":1227968293000},"page":"65-73","source":"Crossref","is-referenced-by-count":20,"title":["Clinical, Anamnestic and Serological Features of Peach Allergy in Portugal"],"prefix":"10.1159","volume":"149","author":[{"given":"Rodrigo","family":"Rodrigues-Alves","sequence":"first","affiliation":[]},{"given":"Anabela","family":"Lopez","sequence":"additional","affiliation":[]},{"given":"Maria Concei\u00e7\u00e3o","family":"Pereira-Santos","sequence":"additional","affiliation":[]},{"given":"Susana","family":"Lopes-Silva","sequence":"additional","affiliation":[]},{"given":"Am\u00e9lia","family":"Sp\u00ednola-Santos","sequence":"additional","affiliation":[]},{"given":"C\u00e9lia","family":"Costa","sequence":"additional","affiliation":[]},{"given":"Manuel","family":"Branco-Ferreira","sequence":"additional","affiliation":[]},{"given":"Jonas","family":"Lidholm","sequence":"additional","affiliation":[]},{"given":"Manuel","family":"Pereira-Barbosa","sequence":"additional","affiliation":[]}],"member":"127","published-online":{"date-parts":[[2008,11,26]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1398-9995.1998.tb03995.x"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1365-2222.1994.tb00911.x"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016%2F0091-6749%2894%2990177-5"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016%2FS0091-6749%2898%2970096-X"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016%2FS0091-6749%2895%2970178-8"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016%2FS0091-6749%2897%2970265-3"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1398-9995.1998.tb03777.x"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1067%2Fmai.2000.106927"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1016%2FS0091-6749%2899%2970479-3"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1159%2F000059401"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1016%2FS1081-1206%2810%2962834-7"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1398-9995.2006.01284.x"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1034%2Fj.1398-9995.2003.00198.x"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1398-9995.2004.00466.x"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1016%2FS0091-6749%2895%2970096-X"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1016%2FS0091-6749%2803%2902016-5"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1398-9995.2007.01448.x"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1016%2FS0091-6749%2899%2970343-X"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1365-2222.2007.02653.x"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1398-9995.2006.00994.x"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1365-2222.2004.02053.x"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1034%2Fj.1398-9995.2002.t01-1-23541.x"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1365-2222.2004.02018.x"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.jmb.2005.11.063"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1016%2FS1081-1206%2810%2961559-1"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1034%2Fj.1398-9995.2002.23626.x"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1067%2Fmai.2002.125830"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.jaci.2006.05.012"},{"key":"ref29","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1365-2222.2006.2492.x"},{"key":"ref30","doi-asserted-by":"publisher","DOI":"10.1034%2Fj.1398-9995.2002.23732.x"},{"key":"ref31","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1365-2222.2004.01837.x"},{"key":"ref32","doi-asserted-by":"publisher","DOI":"10.1067%2Fmai.2003.173"}],"container-title":["International Archives of Allergy and Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/176308","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/176308","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T00:24:09Z","timestamp":1745454249000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000176308"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,11,26]]},"references-count":32,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2009,4,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000176308","archive":["Portico"],"relation":{},"ISSN":["1018-2438","1423-0097"],"issn-type":[{"value":"1018-2438","type":"print"},{"value":"1423-0097","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,11,26]]}}}