{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T20:35:33Z","timestamp":1777926933629,"version":"3.51.4"},"reference-count":0,"publisher":"S. Karger AG","license":[{"start":{"date-parts":[[2009,9,30]],"date-time":"2009-09-30T00:00:00Z","timestamp":1254268800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"},{"start":{"date-parts":[[2009,9,30]],"date-time":"2009-09-30T00:00:00Z","timestamp":1254268800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biol Neonate"],"abstract":"<jats:p>We analyzed nutrient levels in amniotic fluid obtained during the second trimester of normal, uncomplicated pregnancies from 221 women who delivered apparently healthy infants and from 8 with neural tube defect (NTD) pregnancies. Folate was measured by microbiological assay, vitamin B&lt;sub&gt;12&lt;\/sub&gt; by a radiobinding method, and zinc, copper and iron by atomic absorption spectrophotometry. We found that the mean amniotic fluid nutrient levels of normal pregnancies were 24.7nmol\/l for folate, 600pmol\/l for vitamin B&lt;sub&gt;12&lt;\/sub&gt;, and 1.7, 1.9, and 9.0 \u03bcmol\/l for zinc, copper and iron, respectively. Amniotic fluid folate, zinc, copper and iron levels of NTD pregnancies were similar to those found during normal pregnancy, however, vitamin B&lt;sub&gt;12&lt;\/sub&gt; levels were markedly lower than those of normal pregnancies.<\/jats:p>","DOI":"10.1159\/000243747","type":"journal-article","created":{"date-parts":[[2009,10,2]],"date-time":"2009-10-02T05:47:33Z","timestamp":1254462453000},"page":"226-231","source":"Crossref","is-referenced-by-count":36,"title":["Nutrient Levels in Amniotic Fluid from Women with Normal and Neural Tube Defect Pregnancies"],"prefix":"10.1159","author":[{"given":"E.W.","family":"Weekes","sequence":"first","affiliation":[]},{"given":"T.","family":"Tamura","sequence":"additional","affiliation":[]},{"given":"R.O.","family":"Davis","sequence":"additional","affiliation":[]},{"given":"R.","family":"Birch","sequence":"additional","affiliation":[]},{"given":"W.H.","family":"Vaughn","sequence":"additional","affiliation":[]},{"given":"J.C.","family":"Franklin","sequence":"additional","affiliation":[]},{"given":"C.","family":"Barganier","sequence":"additional","affiliation":[]},{"given":"P.","family":"Cosper","sequence":"additional","affiliation":[]},{"given":"S.C.","family":"Finley","sequence":"additional","affiliation":[]},{"given":"W.H.","family":"Finley","sequence":"additional","affiliation":[]}],"member":"127","published-online":{"date-parts":[[2009,9,30]]},"container-title":["Biology of the Neonate"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/243747","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/karger.com\/article-pdf\/doi\/10.1159\/000243747","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T22:26:32Z","timestamp":1777674392000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000243747"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,9,30]]},"references-count":0,"URL":"https:\/\/doi.org\/10.1159\/000243747","archive":["Portico"],"relation":{},"ISSN":["0006-3126","1421-9727"],"issn-type":[{"value":"0006-3126","type":"print"},{"value":"1421-9727","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,9,30]]}}}