{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,24]],"date-time":"2026-04-24T21:59:16Z","timestamp":1777067956219,"version":"3.51.4"},"reference-count":28,"publisher":"S. Karger AG","issue":"2","license":[{"start":{"date-parts":[[2010,9,24]],"date-time":"2010-09-24T00:00:00Z","timestamp":1285286400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2010,9,24]],"date-time":"2010-09-24T00:00:00Z","timestamp":1285286400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ophthalmologica"],"published-print":{"date-parts":[[2011]]},"abstract":"<i>Aim:<\/i> Evaluation of safety and efficacy of intravitreal ranibizumab in the treatment of choroidal neovascularization (CNV) secondary to causes other than age-related macular degeneration (AMD) or pathological myopia (PM). <i>Methods:<\/i> Retrospective and multicentric analysis of 21 eyes with CNV. Nine eyes had angioid streaks, 5 inflammatory chorioretinal diseases, 3 central serous chorioretinopathy and 4 idiopathic CNV. Follow-ups lasted \u22673 months. Best-corrected visual acuity (BCVA), ocular coherence tomography (OCT) and fundus examination were assessed monthly. <i>Results:<\/i> Sixteen eyes (76%) completed 180 days of follow-up. Overall BCVA increased by +9.8 letters with treatment (p = 0.015). Visual acuity improvements \u226715 letters occurred in 43%. A significant reduction in OCT central thickness was observed. No cases of severe visual acuity loss, systemic or ocular side effects were registered. <i>Conclusion:<\/i> Short-term results of intravitreal ranibizumab for CNV unrelated to AMD or PM are encouraging. This treatment may constitute the only option for some of these patients.<\/jats:p>","DOI":"10.1159\/000317908","type":"journal-article","created":{"date-parts":[[2010,9,24]],"date-time":"2010-09-24T08:55:08Z","timestamp":1285318508000},"page":"81-88","source":"Crossref","is-referenced-by-count":32,"title":["Ranibizumab Treatment for Choroidal Neovascularization from Causes Other than Age-Related Macular Degeneration and Pathological Myopia"],"prefix":"10.1159","volume":"225","author":[{"given":"Angela M.","family":"Carneiro","sequence":"first","affiliation":[]},{"given":"Rufino M.","family":"Silva","sequence":"additional","affiliation":[]},{"given":"Maria J.","family":"Veludo","sequence":"additional","affiliation":[]},{"given":"Augusto","family":"Barbosa","sequence":"additional","affiliation":[]},{"given":"Jos\u00e9 M.","family":"Ruiz-Moreno","sequence":"additional","affiliation":[]},{"given":"Manuel S.","family":"Falc\u00e3o","sequence":"additional","affiliation":[]},{"given":"Elisete M.","family":"Brand\u00e3o","sequence":"additional","affiliation":[]},{"given":"Fernando M.","family":"Falc\u00e3o-Reis","sequence":"additional","affiliation":[]}],"member":"127","published-online":{"date-parts":[[2010,9,24]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.ajo.2003.11.069"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1097%2F01.iae.0000242842.14624.e7"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.ophtha.2008.10.018"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.ajo.2007.10.004"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1056%2FNEJMoa062655"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1056%2FNEJMoa054481"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.ophtha.2009.05.024"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.ajo.2009.01.024"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.ophtha.2007.04.030"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1038%2Fsj.eye.6702278"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1159%2F000093071"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1007%2Fs00417-005-0131-3"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1097%2F00006982-200410000-00013"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1097%2FIAE.0b013e31809ff5df"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1001%2Farchopht.125.10.1422"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.ajo.2009.04.026"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1136%2Fbjo.2008.143461"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1001%2Farchopht.126.7.941"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1136%2Fbjo.2008.145896"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1097%2FIAE.0b013e3181c596b1"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1097%2FIAE.0b013e31817eda41"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1097%2FIAE.0b013e3181c9691e"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.ajo.2006.10.050"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.ajo.2007.02.039"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.ajo.2007.01.028"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1159%2F000309793"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1016%2F0039-6257%2882%2990158-8"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.1097%2FIAE.0b013e3181c9699c"}],"container-title":["Ophthalmologica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/317908","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/317908","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T19:31:19Z","timestamp":1745436679000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000317908"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,9,24]]},"references-count":28,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2011,1,1]]},"published-print":{"date-parts":[[2011,1,26]]}},"URL":"https:\/\/doi.org\/10.1159\/000317908","archive":["Portico"],"relation":{},"ISSN":["0030-3755","1423-0267"],"issn-type":[{"value":"0030-3755","type":"print"},{"value":"1423-0267","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,9,24]]}}}