{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T19:16:16Z","timestamp":1761765376285,"version":"3.40.4"},"reference-count":17,"publisher":"S. Karger AG","issue":"5","license":[{"start":{"date-parts":[[2010,11,5]],"date-time":"2010-11-05T00:00:00Z","timestamp":1288915200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2010,11,5]],"date-time":"2010-11-05T00:00:00Z","timestamp":1288915200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Respiration"],"published-print":{"date-parts":[[2011]]},"abstract":"<jats:p>Organizing pneumonia is a pathologic entity characterized by intra-alveolar buds of granulation tissue that can extend to the bronchiolar lumen. It is a non-specific finding reflecting a pattern of pulmonary response to aggression that can be cryptogenic or associated with several causes. Pulmonary actinomycosis is a rare infectious disease, of bacterial aetiology, and of difficult diagnosis. This disease usually causes non-specific respiratory symptoms and radiological findings, and the treatment is based on the use of antibiotics. The authors describe a clinical case of a 53-year-old male smoker (50 pack years), initially seen for complaints of right-sided chest pain and sub-febrile temperature. Imaging studies revealed a mass in the inferior right lobe and enlarged mediastinal lymph nodes. Empirical treatment with antibiotics caused partial and temporary improvement. Transthoracic biopsy revealed a pattern of organizing pneumonia with giant multinucleated cell granulomas. Repeat imaging studies revealed an enlargement of the pulmonary mass and therefore a right inferior lobectomy was performed. The pathologic study revealed a histological pattern of organizing pneumonia surrounding inflammatory bronchiectasis with a large number of &lt;i&gt;Actinomyces&lt;\/i&gt; colonies. To our knowledge there is presently no report in the literature of organizing pneumonia associated with &lt;i&gt;Actinomyces&lt;\/i&gt; infection.<\/jats:p>","DOI":"10.1159\/000321247","type":"journal-article","created":{"date-parts":[[2010,11,5]],"date-time":"2010-11-05T07:54:58Z","timestamp":1288943698000},"page":"433-436","source":"Crossref","is-referenced-by-count":11,"title":["Organizing Pneumonia due to Actinomycosis: An Undescribed Association"],"prefix":"10.1159","volume":"81","author":[{"given":"T.M.","family":"Alfaro","sequence":"first","affiliation":[]},{"given":"J.","family":"Bernardo","sequence":"additional","affiliation":[]},{"given":"H.","family":"Garcia","sequence":"additional","affiliation":[]},{"given":"F.","family":"Alves","sequence":"additional","affiliation":[]},{"given":"L.","family":"Carvalho","sequence":"additional","affiliation":[]},{"given":"F.","family":"Caseiro Alves","sequence":"additional","affiliation":[]},{"given":"C.","family":"Robalo Cordeiro","sequence":"additional","affiliation":[]}],"member":"127","published-online":{"date-parts":[[2010,11,5]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1183%2F09031936.06.00013505"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1001%2Farchinte.161.2.158"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1159%2F000163069"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1159%2F000214841"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1159%2F000085366"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1159%2F000050541"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1378%2Fchest.07-1148"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1007%2Fs00330-001-1211-3"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1097%2F01.mcp.0000175521.41729.07"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1183%2F09031936.04.00074804"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1183%2F09031936.03.00089103"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.2214%2FAJR.04.1749"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1016%2FS1092-9134%2899%2980032-X"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1097%2F01.mcp.0000219273.57933.48"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1159%2F000312404"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1016%2FS0046-8177%2873%2980097-8"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1159%2F000282171"}],"container-title":["Respiration"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/321247","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/321247","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T18:58:11Z","timestamp":1745434691000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000321247"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,11,5]]},"references-count":17,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2011,4,1]]},"published-print":{"date-parts":[[2011,4,19]]}},"URL":"https:\/\/doi.org\/10.1159\/000321247","archive":["Portico"],"relation":{},"ISSN":["0025-7931","1423-0356"],"issn-type":[{"type":"print","value":"0025-7931"},{"type":"electronic","value":"1423-0356"}],"subject":[],"published":{"date-parts":[[2010,11,5]]}}}