{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T12:47:37Z","timestamp":1773319657661,"version":"3.50.1"},"reference-count":15,"publisher":"S. Karger AG","issue":"3","license":[{"start":{"date-parts":[[2012,1,1]],"date-time":"2012-01-01T00:00:00Z","timestamp":1325376000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2012,1,1]],"date-time":"2012-01-01T00:00:00Z","timestamp":1325376000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cardiology"],"published-print":{"date-parts":[[2012]]},"abstract":"<jats:p>&lt;i&gt;Introduction:&lt;\/i&gt; Multiple symmetric lipomatosis (MSL) is a rare disease of unknown etiology characterized by multiple subcutaneous lipomas with a symmetrical distribution. One interesting aspect about MSL is a high incidence of sudden cardiac death despite a low incidence of metabolic syndrome and coronary arterial disease. Autonomic nervous system dysfunction may probably explain this feature of MSL. &lt;i&gt;Case Report:&lt;\/i&gt; A 74-year-old man was admitted with acute heart failure and atrial fibrillation. He had a morphotype suggestive of MLS. A &lt;sup&gt;123&lt;\/sup&gt;I-metaiodobenzylguanidine myocardial scintigraphy was conducted for evaluation of cardiac autonomic nervous integrity, since atrial fibrillation precluded the classical approach. The heart-to-mediastinum ratio was 1.68 (normal &gt;2.2). Ischemia was not detected in myocardial perfusion scintigraphy. &lt;i&gt;Conclusion:&lt;\/i&gt; We present the first reported case of MSL autonomic neuropathy detected by &lt;sup&gt;123&lt;\/sup&gt;I- metaiodobenzylguanidine scintigraphy and suggest that this approach could play a role in MSL stratification by risk of sudden cardiac death and in exploring MSL disease mechanisms.<\/jats:p>","DOI":"10.1159\/000336951","type":"journal-article","created":{"date-parts":[[2012,3,23]],"date-time":"2012-03-23T06:53:33Z","timestamp":1332485613000},"page":"160-163","source":"Crossref","is-referenced-by-count":7,"title":["Cardiac Noradrenergic Denervation in a Patient with Multiple Symmetric Lipomatosis"],"prefix":"10.1159","volume":"121","author":[{"given":"V\u00e1lter R.","family":"Fonseca","sequence":"first","affiliation":[]},{"given":"Carlos","family":"Freitas","sequence":"additional","affiliation":[]},{"given":"Mireille","family":"Palmeira","sequence":"additional","affiliation":[]},{"given":"Carlos","family":"Ferreira","sequence":"additional","affiliation":[]},{"given":"Rui","family":"Victorino","sequence":"additional","affiliation":[]}],"member":"127","published-online":{"date-parts":[[2012,3,22]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1038%2Fsj.ijo.0801867"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1172%2FJCI108881"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016%2FS0031-6989%2880%2980100-7"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1002%2Fpath.1212"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.2337%2Fdiacare.27.3.794"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016%2F0165-1838%2884%2990075-4"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.2337%2Fdiacare.24.10.1793"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1038%2Fsj.ijo.0802427"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1097%2F00005792-198401000-00004"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1161%2F01.CIR.93.5.1043"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1067%2Fmnc.2002.121471"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1007%2Fs12350-010-9239-x"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1053%2Fj.semnuclmed.2011.04.001"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1161%2FCIRCULATIONAHA.106.634949"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.2337%2Fdiacare.26.5.1553"}],"container-title":["Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/336951","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/336951","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/336951","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T19:11:06Z","timestamp":1745435466000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000336951"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012]]},"references-count":15,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2012,5,1]]},"published-print":{"date-parts":[[2012,5,2]]}},"URL":"https:\/\/doi.org\/10.1159\/000336951","archive":["Portico"],"relation":{},"ISSN":["0008-6312","1421-9751"],"issn-type":[{"value":"0008-6312","type":"print"},{"value":"1421-9751","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012]]}}}