{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,6]],"date-time":"2025-11-06T12:20:56Z","timestamp":1762431656141,"version":"3.40.5"},"reference-count":25,"publisher":"S. Karger AG","issue":"6","license":[{"start":{"date-parts":[[2019,1,1]],"date-time":"2019-01-01T00:00:00Z","timestamp":1546300800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2019,1,1]],"date-time":"2019-01-01T00:00:00Z","timestamp":1546300800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["GE Port J Gastroenterol"],"published-print":{"date-parts":[[2019]]},"abstract":"<b><i>Background and Purpose:<\/i><\/b> Patency capsule (PC) examination is usually performed \u2013 previously to capsule endoscopy \u2013 to evaluate small-bowel patency in patients with established Crohn\u2019s disease (CD). The reported PC retention rate is significantly higher than expected. Our aims were to assess small-bowel patency, to determine the precise location of the retained PC in patients with CD, and to determine the false positive rate of evaluation with a radiofrequency identification tag (RFIT) scanner. <b><i>Methods:<\/i><\/b> This is a prospective single-center study including CD patients with clinical indication for small-bowel capsule endoscopy. PillCam\u00ae PC examination was performed on all patients to assess small-bowel patency. On all patients with a positive identification of the PC using an RFIT scanner, 30 h after ingestion, an abdominal CT was performed in order to identify its precise location. <b><i>Results:<\/i><\/b> Fifty-four patients were included. The PC retention rate, according to evaluation with the RFIT scanner, was 20% (in 11 patients) 30 h after ingestion. These patients were then submitted to abdominal CT, which revealed that there was small-bowel retention in 5 cases (9%). Higher CRP levels, penetrating disease, and a history of abdominal surgery were associated with an increased risk of PC retention (<i>p<\/i> = 0.007, <i>p<\/i> = 0.011, and <i>p<\/i> = 0.033, respectively). On multivariate analysis, there was an independent association between small-bowel PC retention and CRP levels &#x3e;5 mg\/dL (OR = 15.5; <i>p<\/i> = 0.03). <b><i>Discussion:<\/i><\/b> The small-bowel PC retention rate (9%) was considerably lower than those found in previous reports. Our results show that, with this protocol, the false-positive cases of RFIT scans or plain abdominal X-rays may be avoided. This may contribute to more extensive application of capsule endoscopy without the risk of small-bowel retention.<\/jats:p>","DOI":"10.1159\/000499722","type":"journal-article","created":{"date-parts":[[2019,5,22]],"date-time":"2019-05-22T21:01:42Z","timestamp":1558558902000},"page":"396-403","source":"Crossref","is-referenced-by-count":13,"title":["Evaluation of Small-Bowel Patency in Crohn\u2019s Disease: Prospective Study with a Patency Capsule and Computed Tomography"],"prefix":"10.1159","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8215-1213","authenticated-orcid":false,"given":"Marco","family":"Silva","sequence":"first","affiliation":[]},{"given":"H\u00e9lder","family":"Cardoso","sequence":"additional","affiliation":[]},{"given":"Rui","family":"Cunha","sequence":"additional","affiliation":[]},{"given":"Armando","family":"Peixoto","sequence":"additional","affiliation":[]},{"given":"Rui","family":"Gaspar","sequence":"additional","affiliation":[]},{"given":"Sara","family":"Gomes","sequence":"additional","affiliation":[]},{"given":"Ana\u00a0Lu\u00edsa","family":"Santos","sequence":"additional","affiliation":[]},{"given":"Susana","family":"Lopes","sequence":"additional","affiliation":[]},{"given":"Guilherme","family":"Macedo","sequence":"additional","affiliation":[]}],"member":"127","published-online":{"date-parts":[[2019,5,22]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.3892\/etm.2013.1113"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1177\/0300060516645420"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2006.00761.x"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1055\/s-2005-870220"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016\/j.dld.2006.01.010"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.14.5269"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1155\/2016\/9657053"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1093\/ecco-jcc\/jjw105"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1016\/j.crohns.2013.09.016"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1055\/s-2005-870264"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1016\/j.gie.2011.05.038"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1016\/j.gie.2007.10.063"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1097\/00054725-200207000-00002"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1007\/s10620-008-0210-5"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1097\/01.mcg.0000225633.14663.64"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1111\/den.12883"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1016\/j.dld.2012.11.004"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1159\/000381471"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1016\/j.gie.2008.06.042"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1177\/1756283X17722744"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1093\/ibd\/izy152"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1007\/s00535-010-0231-7"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1016\/j.trsl.2012.01.001"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1055\/s-0034-1390839"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1093\/ecco-jcc\/jjx064"}],"container-title":["GE - Portuguese Journal of Gastroenterology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/499722","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/499722","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T16:30:48Z","timestamp":1745425848000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000499722"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019]]},"references-count":25,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2019,10,29]]},"published-print":{"date-parts":[[2019,11,19]]}},"URL":"https:\/\/doi.org\/10.1159\/000499722","archive":["Portico"],"relation":{},"ISSN":["2341-4545","2387-1954"],"issn-type":[{"type":"print","value":"2341-4545"},{"type":"electronic","value":"2387-1954"}],"subject":[],"published":{"date-parts":[[2019]]}}}