{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T04:38:39Z","timestamp":1772167119051,"version":"3.50.1"},"reference-count":18,"publisher":"S. Karger AG","issue":"2","license":[{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Port J Public Health"],"published-print":{"date-parts":[[2020]]},"abstract":"<b><i>Introduction:<\/i><\/b> The increase in drug-resistant tuberculosis (TB) threatens global progress in eliminating TB, and constitutes a major challenge for patients, health-care workers and health services. Treatment for multidrug-resistant TB (MDR-TB) can last almost 2 years, and is more expensive, more toxic, and less effective than treating TB caused by drug-sensitive bacilli. This study aims to analyze patients\u2019 narratives about the challenges they face during MDR-TB treatment and identify the support factors that help patients being treated in the most populous district of Portugal. <b><i>Methods:<\/i><\/b> Semi-structured interviews were conducted with patients being treated for MDR-TB. The interviews were coded using thematic analysis. They were audio-recorded, transcribed, and transported into NVivo v12 for data management and coding. <b><i>Results:<\/i><\/b> Depression, social discrimination, and the side effects of drugs are the main challenges faced by patients with MDR-TB. A good relationship of the patients with the health team, emotional support, and supervised treatment stand out as the factors that generate better adherence and treatment success. <b><i>Conclusion:<\/i><\/b> In addition to modern diagnostic techniques and new treatments, MDR-TB can be fought by focusing on the care and needs of patients. We suggest that the Lisbon Tuberculosis Program adopts the following measures: build the health-care team\u2019s capacity to identify symptoms of depression early, increase public awareness of the disease, expand the multidisciplinary team, and expand the options for individualized social support for patients. <\/jats:p>","DOI":"10.1159\/000511198","type":"journal-article","created":{"date-parts":[[2020,11,16]],"date-time":"2020-11-16T09:21:26Z","timestamp":1605518486000},"page":"62-70","source":"Crossref","is-referenced-by-count":6,"title":["Multidrug-Resistant Tuberculosis in Portugal: Patients\u2019 Perception of the Challenges Faced during Treatment"],"prefix":"10.1159","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1568-026X","authenticated-orcid":false,"given":"Marcela","family":"Bhering","sequence":"first","affiliation":[]},{"given":"Vicente\u00a0","family":"Sarubbi\u00a0Junior","sequence":"additional","affiliation":[]},{"given":"Afr\u00e2nio","family":"Kritski","sequence":"additional","affiliation":[]},{"given":"Fabiana\u00a0Barbosa\u00a0Assump\u00e7\u00e3o","family":"Souza","sequence":"additional","affiliation":[]},{"given":"Raquel","family":"Duarte","sequence":"additional","affiliation":[]}],"member":"127","published-online":{"date-parts":[[2020,11,13]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-018-23344-z"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1111\/resp.13311"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1093\/intqhc\/mzm042"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1590\/S0102-311X2011000200020"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016\/j.pulmoe.2019.02.005"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016\/S0163-8343(01)00116-5"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.3402\/gha.v7.24912"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0147397"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1590\/0034-7167.2016690316i"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1177\/00333549101250S407"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2458-7-211"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.5588\/ijtld.18.0596"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1186\/s12879-019-4189-7"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.5123\/S1679-49742013000100008"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.0040238"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1590\/S0104-11692012000200021"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201710-2141OC"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1590\/S1806-37132010000500017"}],"container-title":["Portuguese Journal of Public Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/511198","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/511198","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T16:04:24Z","timestamp":1745424264000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000511198"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020]]},"references-count":18,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2021,1,4]]},"published-print":{"date-parts":[[2021,1,12]]}},"URL":"https:\/\/doi.org\/10.1159\/000511198","archive":["Portico"],"relation":{},"ISSN":["2504-3137","2504-3145"],"issn-type":[{"value":"2504-3137","type":"print"},{"value":"2504-3145","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020]]}}}