{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T10:06:01Z","timestamp":1751364361883,"version":"3.40.4"},"reference-count":37,"publisher":"S. Karger AG","issue":"4","license":[{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Obes Facts"],"published-print":{"date-parts":[[2021]]},"abstract":"<jats:p>Bariatric surgery is a very effective treatment for obesity-associated type 2 diabetes. However, the benefits of bariatric surgery in patients with obesity and autoimmune diabetes, such as type 1 diabetes and latent autoimmune diabetes in adults (LADA), are controversial. We report 3 female patients with obesity and LADA who underwent laparoscopic Roux-en-Y gastric bypass &amp;#x3e;10 years ago. The patients were diagnosed with LADA both 1 and 9 years before (&lt;i&gt;n&lt;\/i&gt; = 2) or 11 years after the surgery (&lt;i&gt;n&lt;\/i&gt; = 1). Patients preoperative body mass index ranged from 36 to 47 kg\/m&lt;sup&gt;2&lt;\/sup&gt; and improved to 23\u201337 kg\/m&lt;sup&gt;2&lt;\/sup&gt; in the last follow-up visit, 10\u201315 years after surgery. Daily insulin dose also decreased from an average of 0.68 to 0.45 IU\/kg in those patients treated with insulin before bariatric surgery. Only one patient developed diabetes-related target organ damage. This study shows that patients with LADA depict remarkable reduction of body weight and insulin requirements over long-term after bariatric surgery. So, LADA should not be considered a contraindication for bariatric surgery yet should only be recommended for patients with concomitant obesity with the primary aim of achieving sustained weight loss. <\/jats:p>","DOI":"10.1159\/000517588","type":"journal-article","created":{"date-parts":[[2021,7,28]],"date-time":"2021-07-28T21:01:47Z","timestamp":1627506107000},"page":"425-430","source":"Crossref","is-referenced-by-count":2,"title":["Bariatric Surgery Outcomes in Patients with Latent Autoimmune Diabetes of the Adult"],"prefix":"10.1159","volume":"14","author":[{"given":"Marta","family":"Guimar\u00e3es","sequence":"first","affiliation":[]},{"given":"Sofia S.","family":"Pereira","sequence":"additional","affiliation":[]},{"given":"M\u00e1rio","family":"Nora","sequence":"additional","affiliation":[]},{"given":"Mariana P.","family":"Monteiro","sequence":"additional","affiliation":[]}],"member":"127","published-online":{"date-parts":[[2021,7,28]]},"reference":[{"doi-asserted-by":"publisher","key":"ref1","DOI":"10.2337\/diab.35.2.237"},{"doi-asserted-by":"publisher","key":"ref2","DOI":"10.2337\/ds15-0047"},{"doi-asserted-by":"publisher","key":"ref3","DOI":"10.2337\/dc15-s005"},{"doi-asserted-by":"publisher","key":"ref4","DOI":"10.1023\/a:1025148211587"},{"doi-asserted-by":"publisher","key":"ref5","DOI":"10.1016\/S0140-6736(13)62219-9"},{"doi-asserted-by":"publisher","key":"ref6","DOI":"10.1007\/s00125-018-4596-0"},{"doi-asserted-by":"publisher","key":"ref7","DOI":"10.1210\/jc.2019-00183"},{"doi-asserted-by":"publisher","key":"ref8","DOI":"10.2337\/diacare.23.9.1326"},{"doi-asserted-by":"publisher","key":"ref9","DOI":"10.2337\/db11-0364"},{"doi-asserted-by":"publisher","key":"ref10","DOI":"10.1155\/2016\/6170719"},{"doi-asserted-by":"publisher","key":"ref11","DOI":"10.1038\/ijo.2009.97"},{"doi-asserted-by":"publisher","key":"ref12","DOI":"10.4093\/dmj.2018.0190"},{"doi-asserted-by":"publisher","key":"ref13","DOI":"10.1210\/clinem\/dgaa549"},{"doi-asserted-by":"publisher","key":"ref14","DOI":"10.1210\/jc.2009-1120"},{"doi-asserted-by":"publisher","key":"ref15","DOI":"10.2337\/dc13-0564"},{"doi-asserted-by":"publisher","key":"ref16","DOI":"10.2337\/diacare.22.8.1347"},{"doi-asserted-by":"publisher","key":"ref17","DOI":"10.1016\/j.jdiacomp.2014.11.001"},{"doi-asserted-by":"publisher","key":"ref18","DOI":"10.1111\/j.1464-5491.2008.02562.x"},{"doi-asserted-by":"publisher","key":"ref19","DOI":"10.1001\/jama.295.14.1707"},{"doi-asserted-by":"publisher","key":"ref20","DOI":"10.1007\/s11695-016-2271-4"},{"doi-asserted-by":"publisher","key":"ref21","DOI":"10.2337\/dc19-2388"},{"doi-asserted-by":"publisher","key":"ref22","DOI":"10.1007\/s11695-016-2390-y"},{"doi-asserted-by":"publisher","key":"ref23","DOI":"10.3305\/nh.2013.28.sup2.6711"},{"doi-asserted-by":"publisher","key":"ref24","DOI":"10.1016\/j.soard.2014.12.016"},{"doi-asserted-by":"publisher","key":"ref25","DOI":"10.2337\/dc13-0810"},{"doi-asserted-by":"publisher","key":"ref26","DOI":"10.1210\/jc.2014-1191"},{"doi-asserted-by":"publisher","key":"ref27","DOI":"10.3389\/fphys.2019.01607"},{"doi-asserted-by":"publisher","key":"ref28","DOI":"10.1152\/ajpregu.00926.2007"},{"doi-asserted-by":"publisher","key":"ref29","DOI":"10.1136\/bmj.f5934"},{"doi-asserted-by":"publisher","key":"ref30","DOI":"10.1371\/journal.pone.0224828"},{"doi-asserted-by":"publisher","key":"ref31","DOI":"10.1007\/s11695-018-3252-6"},{"doi-asserted-by":"publisher","key":"ref32","DOI":"10.1001\/jamasurg.2014.467"},{"doi-asserted-by":"publisher","key":"ref33","DOI":"10.1002\/dmrr.3042"},{"doi-asserted-by":"publisher","key":"ref34","DOI":"10.1210\/endrev\/bnaa004"},{"doi-asserted-by":"publisher","key":"ref35","DOI":"10.1002\/mnfr.201400521"},{"doi-asserted-by":"publisher","key":"ref36","DOI":"10.1177\/2042018819877303"},{"doi-asserted-by":"publisher","key":"ref37","DOI":"10.1055\/s-2007-982502"}],"container-title":["Obesity Facts"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/517588","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/517588","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T15:06:54Z","timestamp":1745420814000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000517588"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021]]},"references-count":37,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2021,8,3]]},"published-print":{"date-parts":[[2021,8,5]]}},"URL":"https:\/\/doi.org\/10.1159\/000517588","archive":["Portico"],"relation":{},"ISSN":["1662-4025","1662-4033"],"issn-type":[{"type":"print","value":"1662-4025"},{"type":"electronic","value":"1662-4033"}],"subject":[],"published":{"date-parts":[[2021]]}}}