{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T13:27:04Z","timestamp":1772112424608,"version":"3.50.1"},"reference-count":37,"publisher":"S. Karger AG","issue":"5","license":[{"start":{"date-parts":[[2022,10,27]],"date-time":"2022-10-27T00:00:00Z","timestamp":1666828800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2022,10,27]],"date-time":"2022-10-27T00:00:00Z","timestamp":1666828800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["GE Port J Gastroenterol"],"published-print":{"date-parts":[[2023]]},"abstract":"<jats:p>Background: Colorectal cancer (CRC) is a leading cause of cancer. The detection of pre-malignant lesions by colonoscopy is associated with reduced CRC incidence and mortality. Narrow band imaging has shown promising but conflicting results for the detection of serrated lesions. Methods: We performed a randomized clinical trial to compare the mean detection of serrated lesions and hyperplastic polyps \u226510 mm with NBI or high-definition white light (HD-WL) withdrawal. We also compared all sessile serrated lesions (SSLs), adenoma, and polyp prevalence and rates. Results: Overall, 782 patients were randomized (WL group 392 patients; NBI group 390 patients). The average number of serrated lesions and hyperplastic polyps \u226510 mm detected per colonoscopy (primary endpoint) was similar between the HD-WL and NBI group (0.118 vs. 0.156, p = 0.44). Likewise, the adenoma detection rate (55.2% vs. 53.2%, p = 0.58) and SSL detection rate (6.8% vs. 7.5%, p = 0.502) were not different between the two study groups. Withdrawal time was higher in the NBI group (10.88 vs. 9.47 min, p = 0.004), with a statistically nonsignificant higher total procedure time (20.97 vs. 19.30 min, p = 0.052). Conclusions: The routine utilization of narrow band imaging does not improve the detection of serrated class lesions or any pre-malignant lesion and increases the withdrawal time. <\/jats:p>","DOI":"10.1159\/000526606","type":"journal-article","created":{"date-parts":[[2022,10,27]],"date-time":"2022-10-27T21:00:38Z","timestamp":1666904438000},"page":"368-374","source":"Crossref","is-referenced-by-count":4,"title":["Narrow Band Imaging versus White Light for the Detection of Sessile Serrated Colorectal Lesions: A Randomized Clinical Trial"],"prefix":"10.1159","volume":"30","author":[{"given":"Alexandre Oliveira","family":"Ferreira","sequence":"first","affiliation":[]},{"given":"Joana Branco","family":"Reves","sequence":"additional","affiliation":[]},{"given":"Catarina","family":"Nascimento","sequence":"additional","affiliation":[]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2096-2744","authenticated-orcid":false,"given":"Catarina","family":"Frias-Gomes","sequence":"additional","affiliation":[]},{"given":"Maria Pia","family":"Costa-Santos","sequence":"additional","affiliation":[]},{"given":"L\u00eddia Roque","family":"Ramos","sequence":"additional","affiliation":[]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7978-4287","authenticated-orcid":false,"given":"Carolina","family":"Palmela","sequence":"additional","affiliation":[]},{"given":"Lu\u00edsa","family":"Gloria","sequence":"additional","affiliation":[]},{"given":"Mar\u00edlia","family":"Cravo","sequence":"additional","affiliation":[]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0121-6850","authenticated-orcid":false,"given":"M\u00e1rio","family":"Dinis-Ribeiro","sequence":"additional","affiliation":[]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2539-5876","authenticated-orcid":false,"given":"Jorge","family":"Canena","sequence":"additional","affiliation":[]}],"member":"127","published-online":{"date-parts":[[2022,10,27]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.28509"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1315870"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1300720"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1301969"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1100370"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1114635"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199312303292701"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21457"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2017.05.013"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1055\/s-0043-102569"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2016.3332"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1055\/s-0043-103411"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1016\/j.gie.2014.07.058"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMc1405329"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1055\/s-2007-995618"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa031618"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1016\/s0016-5085(97)70214-2"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2010.06.028"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2012.161"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1055\/s-0034-1365348"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1016\/j.gie.2014.06.043"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1016\/j.gie.2015.03.1915"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.17305\/bjbms.2017.1686"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.4253\/wjge.v9.i6.273"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2014.83"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2011-300187"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1016\/j.gie.2019.06.041"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbi.2019.103208"},{"key":"ref29","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbi.2008.08.010"},{"key":"ref30","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2013-305973"},{"key":"ref31","doi-asserted-by":"publisher","DOI":"10.1055\/s-2005-861352"},{"key":"ref32","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2010.09.013"},{"key":"ref33","doi-asserted-by":"publisher","DOI":"10.1055\/s-0033-1358800"},{"key":"ref34","doi-asserted-by":"publisher","DOI":"10.1159\/000450901"},{"key":"ref35","doi-asserted-by":"publisher","DOI":"10.17235\/reed.2021.8104\/2021"},{"key":"ref36","doi-asserted-by":"publisher","DOI":"10.1159\/000495258"},{"key":"ref37","doi-asserted-by":"publisher","DOI":"10.1159\/000487470"}],"container-title":["GE - Portuguese Journal of Gastroenterology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/karger.com\/pjg\/article-pdf\/30\/5\/368\/4009900\/000526606.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/karger.com\/pjg\/article-pdf\/30\/5\/368\/4009900\/000526606.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T15:17:34Z","timestamp":1745421454000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000526606"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,10,27]]},"references-count":37,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2023,10,3]]},"published-print":{"date-parts":[[2023,9,27]]}},"URL":"https:\/\/doi.org\/10.1159\/000526606","archive":["Portico"],"relation":{},"ISSN":["2341-4545","2387-1954"],"issn-type":[{"value":"2341-4545","type":"print"},{"value":"2387-1954","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,10,27]]}}}