{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T18:45:25Z","timestamp":1791225925965,"version":"4.1.0"},"reference-count":146,"publisher":"Georg Thieme Verlag KG","issue":"12","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Thromb Haemost"],"published-print":{"date-parts":[[2011]]},"abstract":"<jats:title>Summary<\/jats:title>\n                  <jats:p>In this executive summary of a Consensus Document from the European Heart Rhythm Association, endorsed by the European Society of Cardiology Working Group on Thrombosis, we comprehensively review the published evidence and propose a consensus on bleeding risk assessments in atrial fibrillation (AF) patients. The main aim of the document was to summarise \u2018best practice\u2019 in dealing with bleeding risk in AF patients when approaching antithrombotic therapy, by addressing the epidemiology and size of the problem, and review established bleeding risk factors. We also summarise definitions of bleeding in the published literature. Patient values and preferences balancing the risk of bleeding against thromboembolism as well as the prognostic implications of bleeding are reviewed. We also provide an overview of published bleeding risk stratification and bleeding risk schema. Brief discussion of special situations (e.g. periablation, peri-devices such as implantable cardioverter defibrillators [ICD] or pacemakers, presentation with acute coronary syndromes and\/or requiring percutanous coronary interventions\/stents and bridging therapy) is made, as well as a discussion of the prevention of bleeds and managing bleeding complications. Finally, this document puts forwards consensus statements that may help to define evidence gaps and assist in everyday clinical practice.<\/jats:p>","DOI":"10.1160\/th11-10-0690","type":"journal-article","created":{"date-parts":[[2011,11,2]],"date-time":"2011-11-02T11:45:36Z","timestamp":1320234336000},"page":"997-1011.","source":"Crossref","is-referenced-by-count":199,"title":["Bleeding risk assessment and management in atrial fibrillation patients"],"prefix":"10.1160","volume":"106","author":[{"given":"Laurent","family":"Fauchier","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elaine","family":"Hylek","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eve","family":"Knight","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deirdre","family":"Lane","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcel","family":"Levi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francisco","family":"Marin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gualtiero","family":"Palareti","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.-P.","family":"Collet","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Rubboli","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Poli","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A. J.","family":"Camm","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gregory","family":"Lip","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Felicita","family":"Andreotti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kurt","family":"Huber","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paulus","family":"Kirchhof","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2017,12,15]]},"reference":[{"key":"10.1160\/TH11-10-0690-1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehm358"},{"key":"10.1160\/TH11-10-0690-2","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/euq160"},{"key":"10.1160\/TH11-10-0690-3","doi-asserted-by":"crossref","first-page":"297","DOI":"10.7326\/0003-4819-151-5-200909010-00003","volume":"151","author":"Singer","year":"2009","journal-title":"Ann Intern Med"},{"key":"10.1160\/TH11-10-0690-4","doi-asserted-by":"publisher","DOI":"10.1160\/TH09-05-0327"},{"key":"10.1160\/TH11-10-0690-5","doi-asserted-by":"publisher","DOI":"10.1160\/TH10-10-0642"},{"key":"10.1160\/TH11-10-0690-6","doi-asserted-by":"publisher","DOI":"10.1160\/TH10-10-0674"},{"key":"10.1160\/TH11-10-0690-7","doi-asserted-by":"publisher","DOI":"10.1001\/jama.285.22.2864"},{"key":"10.1160\/TH11-10-0690-8","doi-asserted-by":"publisher","DOI":"10.1378\/chest.09-1584"},{"key":"10.1160\/TH11-10-0690-9","doi-asserted-by":"publisher","DOI":"10.1160\/TH10-01-0038"},{"key":"10.1160\/TH11-10-0690-10","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/eur126"},{"key":"10.1160\/TH11-10-0690-11","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000250340.05202.8b"},{"key":"10.1160\/TH11-10-0690-12","doi-asserted-by":"crossref","unstructured":"Nieuwlaat R, et al.; on behalf of the Euro Heart Survey Investigators. Antithrombotic treatment in real-life atrial fibrillation patients: a report from the Euro Heart Survey on Atrial Fibrillation. Eur Heart J 2006; 27: 3018-3026.","DOI":"10.1093\/eurheartj\/ehl015"},{"key":"10.1160\/TH11-10-0690-13","doi-asserted-by":"publisher","DOI":"10.1160\/TH09-08-0525"},{"key":"10.1160\/TH11-10-0690-14","doi-asserted-by":"publisher","DOI":"10.1160\/TH10-07-0491"},{"key":"10.1160\/TH11-10-0690-15","doi-asserted-by":"crossref","unstructured":"Ezekowitz MD, et al.; the RE-LY Steering Committee and Investigators. Dabigatran and Warfarin in Vitamin K Antagonist-Naive and -Experienced Cohorts With Atrial Fibrillation. Circulation 2010; 122: 2246-2253.","DOI":"10.1161\/CIRCULATIONAHA.110.973735"},{"key":"10.1160\/TH11-10-0690-16","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.1994.00420130036007"},{"key":"10.1160\/TH11-10-0690-17","first-page":"687","volume":"343","author":"SPAF","year":"1994","journal-title":"Lancet"},{"key":"10.1160\/TH11-10-0690-18","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2004.11.015"},{"key":"10.1160\/TH11-10-0690-19","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(03)14841-6"},{"key":"10.1160\/TH11-10-0690-20","doi-asserted-by":"publisher","DOI":"10.1001\/jama.293.6.690"},{"key":"10.1160\/TH11-10-0690-21","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(06)68845-4"},{"key":"10.1160\/TH11-10-0690-22","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0905561"},{"key":"10.1160\/TH11-10-0690-23","doi-asserted-by":"crossref","unstructured":"Patel MR, et al.; ROCKET AF Investigators. Rivaroxaban versus warfarin in nonvalvular atrial fibrillation. N Engl J Med 2011; 365: 883-891.","DOI":"10.1056\/NEJMoa1009638"},{"key":"10.1160\/TH11-10-0690-24","doi-asserted-by":"crossref","unstructured":"Granger CB, et al.; ARISTOTLE Committees and Investigators. Apixaban versus warfarin in patients with atrial fibrillation. N Engl J Med 2011; 365: 981-992.","DOI":"10.1056\/NEJMoa1107039"},{"key":"10.1160\/TH11-10-0690-25","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9343(89)80689-8"},{"key":"10.1160\/TH11-10-0690-26","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2796.1997.tb00023.x"},{"key":"10.1160\/TH11-10-0690-27","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9343(98)00198-3"},{"key":"10.1160\/TH11-10-0690-28","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.106.653048"},{"key":"10.1160\/TH11-10-0690-29","doi-asserted-by":"crossref","unstructured":"Pengo V, et al.; ISCOAT Study Group.(Italian Study on Complications of Oral Anticoagulant Therapy). Oral Anticoagulant Therapy in Patients with Nonrheumatic Atrial Fibrillation and Risk of Bleed. A Multicenter Inception Cohort Study. Thromb Haemost 2001; 85: 418-422","DOI":"10.1055\/s-0037-1615599"},{"key":"10.1160\/TH11-10-0690-30","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.1993.00410130073007"},{"key":"10.1160\/TH11-10-0690-31","doi-asserted-by":"crossref","first-page":"511","DOI":"10.7326\/0003-4819-118-7-199304010-00005","volume":"118","author":"Fihn","year":"1993","journal-title":"Ann Intern Med"},{"key":"10.1160\/TH11-10-0690-32","doi-asserted-by":"publisher","DOI":"10.1001\/jama.290.20.2685"},{"key":"10.1160\/TH11-10-0690-33","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2009.05.046"},{"key":"10.1160\/TH11-10-0690-34","doi-asserted-by":"publisher","DOI":"10.1111\/j.1538-7836.2008.03075.x"},{"key":"10.1160\/TH11-10-0690-35","doi-asserted-by":"crossref","unstructured":"Poli D, et al.; Italian Federation of Anticoagulation Clinics. Bleeding risk in very old patients on vitamin K antagonist treatment: results of a prospective collaborative study on elderly patients followed by Italian Centres for Anticoagulation. Circulation 2011; 124: 824-829.","DOI":"10.1161\/CIRCULATIONAHA.110.007864"},{"key":"10.1160\/TH11-10-0690-36","doi-asserted-by":"publisher","DOI":"10.2165\/00002512-199914040-00005"},{"key":"10.1160\/TH11-10-0690-37","doi-asserted-by":"crossref","first-page":"745","DOI":"10.7326\/0003-4819-141-10-200411160-00005","volume":"141","author":"Fang","year":"2004","journal-title":"Ann Intern Med"},{"key":"10.1160\/TH11-10-0690-38","doi-asserted-by":"publisher","DOI":"10.1016\/j.ehj.2004.06.030"},{"key":"10.1160\/TH11-10-0690-39","doi-asserted-by":"publisher","DOI":"10.1160\/TH11-05-0364"},{"key":"10.1160\/TH11-10-0690-40","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2007.04.009"},{"key":"10.1160\/TH11-10-0690-41","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.76.1.142"},{"key":"10.1160\/TH11-10-0690-42","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199309023291001"},{"key":"10.1160\/TH11-10-0690-43","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.110.009449"},{"key":"10.1160\/TH11-10-0690-44","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1160\/TH08-11-0730","volume":"102","author":"Palareti","year":"2009","journal-title":"Thromb Haemost"},{"key":"10.1160\/TH11-10-0690-45","doi-asserted-by":"publisher","DOI":"10.1093\/qjmed\/hcm076"},{"key":"10.1160\/TH11-10-0690-46","doi-asserted-by":"crossref","unstructured":"Schulman S, et al.; Subcommittee on Control of Anticoagulation of the Scientific and Standardization Committee of the International Society on Thrombosis and Haemostasis. Definition of major bleeding in clinical investigations of antihemostatic medicinal products in surgical patients. J Thromb Haemost 2010; 8: 202-204.","DOI":"10.1111\/j.1538-7836.2009.03678.x"},{"key":"10.1160\/TH11-10-0690-47","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(01)05775-0"},{"key":"10.1160\/TH11-10-0690-48","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa010746"},{"key":"10.1160\/TH11-10-0690-49","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(07)60450-4"},{"key":"10.1160\/TH11-10-0690-50","doi-asserted-by":"publisher","DOI":"10.1001\/jama.295.13.joc60038"},{"key":"10.1160\/TH11-10-0690-51","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0904327"},{"key":"10.1160\/TH11-10-0690-52","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(96)01109-9"},{"key":"10.1160\/TH11-10-0690-53","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.159.5.457"},{"key":"10.1160\/TH11-10-0690-54","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.163.8.917"},{"key":"10.1160\/TH11-10-0690-55","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-1497.2005.0229.x"},{"key":"10.1160\/TH11-10-0690-56","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2005.04.017"},{"key":"10.1160\/TH11-10-0690-57","doi-asserted-by":"publisher","DOI":"10.1378\/chest.130.5.1390"},{"key":"10.1160\/TH11-10-0690-58","doi-asserted-by":"crossref","unstructured":"Ru\u00edz-Gim\u00e9nez N, et al.; RIETE Investigators. Predictive variables for major bleeding events inpatients presenting with documented acute venous thromboembolism. Findings fromthe RIETE Registry. Thromb Haemost 2008; 100: 26-31.","DOI":"10.1160\/TH08-03-0193"},{"key":"10.1160\/TH11-10-0690-59","doi-asserted-by":"publisher","DOI":"10.3949\/ccjm.77a.10018"},{"key":"10.1160\/TH11-10-0690-60","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199002153220703"},{"key":"10.1160\/TH11-10-0690-61","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2003.07.029"},{"key":"10.1160\/TH11-10-0690-62","doi-asserted-by":"crossref","first-page":"897","DOI":"10.7326\/0003-4819-120-11-199406010-00001","volume":"120","author":"Hylek","year":"1994","journal-title":"Ann Intern Med"},{"key":"10.1160\/TH11-10-0690-63","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199507063330103"},{"key":"10.1160\/TH11-10-0690-64","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.167.3.239"},{"key":"10.1160\/TH11-10-0690-65","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.107.750000"},{"key":"10.1160\/TH11-10-0690-66","doi-asserted-by":"publisher","DOI":"10.1378\/chest.129.5.1155"},{"key":"10.1160\/TH11-10-0690-67","doi-asserted-by":"crossref","unstructured":"Matchar DB, et al.; THINRS Executive Committee and Site Investigators. Effect of home testing of international normalized ratio on clinical events. N Engl J Med 2010; 363: 1608-1620.","DOI":"10.1056\/NEJMoa1002617"},{"key":"10.1160\/TH11-10-0690-68","doi-asserted-by":"publisher","DOI":"10.1055\/s-0029-1240016"},{"key":"10.1160\/TH11-10-0690-69","doi-asserted-by":"publisher","DOI":"10.1001\/jama.287.13.1690"},{"key":"10.1160\/TH11-10-0690-70","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.0020312"},{"key":"10.1160\/TH11-10-0690-71","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinthera.2010.06.010"},{"key":"10.1160\/TH11-10-0690-72","doi-asserted-by":"publisher","DOI":"10.1038\/jhh.2010.57"},{"key":"10.1160\/TH11-10-0690-73","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2007-11-123711"},{"key":"10.1160\/TH11-10-0690-74","doi-asserted-by":"publisher","DOI":"10.1159\/000015958"},{"key":"10.1160\/TH11-10-0690-75","doi-asserted-by":"crossref","first-page":"241","DOI":"10.7326\/0003-4819-143-4-200508160-00005","volume":"143","author":"Rothberg","year":"2005","journal-title":"Ann Intern Med"},{"key":"10.1160\/TH11-10-0690-76","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.38947.697558.AE"},{"key":"10.1160\/TH11-10-0690-77","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(09)61751-7"},{"key":"10.1160\/TH11-10-0690-78","doi-asserted-by":"publisher","DOI":"10.1046\/j.0306-5251.2001.01220.x"},{"key":"10.1160\/TH11-10-0690-79","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.165.2.189"},{"key":"10.1160\/TH11-10-0690-80","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.159.7.677"},{"key":"10.1160\/TH11-10-0690-81","doi-asserted-by":"crossref","first-page":"1047","DOI":"10.1160\/TH08-08-0530","volume":"100","author":"Levi","year":"2008","journal-title":"Thromb Haemost"},{"key":"10.1160\/TH11-10-0690-82","doi-asserted-by":"publisher","DOI":"10.1378\/chest.10-0134"},{"key":"10.1160\/TH11-10-0690-83","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2011.03.031"},{"key":"10.1160\/TH11-10-0690-84","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2010.09.024"},{"key":"10.1160\/TH11-10-0690-85","doi-asserted-by":"publisher","DOI":"10.1111\/j.1538-7836.2011.04378.x"},{"key":"10.1160\/TH11-10-0690-86","doi-asserted-by":"crossref","unstructured":"Cairns JA, et al.; CCS Atrial Fibrillation Guidelines Committee. Canadian cardiovascular society atrial fibrillation guidelines 2010: prevention of stroke and systemic thromboembolism in atrial fibrillation and flutter. Can J Cardiol 2011; 27: 74-90.","DOI":"10.1016\/j.cjca.2010.11.007"},{"key":"10.1160\/TH11-10-0690-87","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2005.07.031"},{"key":"10.1160\/TH11-10-0690-88","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejim.2006.11.005"},{"key":"10.1160\/TH11-10-0690-89","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2296-5-15"},{"key":"10.1160\/TH11-10-0690-90","unstructured":"Department of Health. Patient and public involvement in the new NHS. London: Department of Health, 1999."},{"key":"10.1160\/TH11-10-0690-91","doi-asserted-by":"publisher","DOI":"10.1001\/jama.274.23.1839"},{"key":"10.1160\/TH11-10-0690-92","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.1996.00440150083009"},{"key":"10.1160\/TH11-10-0690-93","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.1996.00440150095011"},{"key":"10.1160\/TH11-10-0690-94","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.29.6.1083"},{"key":"10.1160\/TH11-10-0690-95","first-page":"1775","volume":"48","author":"Sudlow","year":"1998","journal-title":"Br J Gen Pract"},{"key":"10.1160\/TH11-10-0690-96","doi-asserted-by":"publisher","DOI":"10.1001\/jama.282.8.737"},{"key":"10.1160\/TH11-10-0690-97","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.318.7194.1324"},{"key":"10.1160\/TH11-10-0690-98","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.320.7246.1380"},{"key":"10.1160\/TH11-10-0690-99","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(00)90012-6"},{"key":"10.1160\/TH11-10-0690-100","doi-asserted-by":"publisher","DOI":"10.1503\/cmaj.050091"},{"key":"10.1160\/TH11-10-0690-101","doi-asserted-by":"publisher","DOI":"10.1136\/qshc.2006.018481"},{"key":"10.1160\/TH11-10-0690-102","doi-asserted-by":"crossref","unstructured":"Devereaux PJ, et al. Differences between perspectives of physicians and patients on anticoagulation in patients with atrial fibrillation; observational study. Br Med J 2001; 323: 1-7.","DOI":"10.1136\/bmj.323.7323.1218"},{"key":"10.1160\/TH11-10-0690-103","doi-asserted-by":"publisher","DOI":"10.1093\/ageing\/afh202"},{"key":"10.1160\/TH11-10-0690-104","doi-asserted-by":"publisher","DOI":"10.1046\/j.1369-6513.2002.00188.x"},{"key":"10.1160\/TH11-10-0690-105","doi-asserted-by":"publisher","DOI":"10.1503\/cmaj.060837"},{"key":"10.1160\/TH11-10-0690-106","doi-asserted-by":"publisher","DOI":"10.1186\/1472-6963-8-221"},{"key":"10.1160\/TH11-10-0690-107","doi-asserted-by":"publisher","DOI":"10.1093\/ageing\/30.6.473"},{"key":"10.1160\/TH11-10-0690-108","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/euq109"},{"key":"10.1160\/TH11-10-0690-109","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.109.859116"},{"key":"10.1160\/TH11-10-0690-110","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/eun104"},{"key":"10.1160\/TH11-10-0690-111","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2009.07.007"},{"key":"10.1160\/TH11-10-0690-112","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8159.2009.02429.x"},{"key":"10.1160\/TH11-10-0690-113","unstructured":"Vardas PE, et al.; European Society of Cardiology; European Heart Rhythm Association. Guidelines for cardiac pacing and cardiac resynchronization therapy. The Task Force for Cardiac Pacing and Cardiac Resynchronization Therapy of the European Society of Cardiology. Developed in collaboration with the European Heart Rhythm Association. Europace. 2007; 9: 959-998."},{"key":"10.1160\/TH11-10-0690-114","doi-asserted-by":"publisher","DOI":"10.1378\/chest.08-0675"},{"key":"10.1160\/TH11-10-0690-115","doi-asserted-by":"publisher","DOI":"10.1111\/j.1538-7836.2008.03080.x"},{"key":"10.1160\/TH11-10-0690-116","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehp194"},{"key":"10.1160\/TH11-10-0690-117","doi-asserted-by":"publisher","DOI":"10.1160\/TH09-08-0580"},{"key":"10.1160\/TH11-10-0690-118","doi-asserted-by":"crossref","unstructured":"Agostoni P, et al. Radial versus femoral approach for percutaneous coronary diagnostic and interventional procedures; Systematic overview and meta-analysis of randomized trials. J Am Coll Cardiol 2004; 44: 349-356.","DOI":"10.1016\/j.jacc.2004.04.034"},{"key":"10.1160\/TH11-10-0690-119","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2008.08.023"},{"key":"10.1160\/TH11-10-0690-120","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2008.08.021"},{"key":"10.1160\/TH11-10-0690-121","doi-asserted-by":"publisher","DOI":"10.1160\/TH11-04-0262"},{"key":"10.1160\/TH11-10-0690-122","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2008.08.002"},{"key":"10.1160\/TH11-10-0690-123","doi-asserted-by":"publisher","DOI":"10.1378\/chest.08-0670"},{"key":"10.1160\/TH11-10-0690-124","doi-asserted-by":"publisher","DOI":"10.1378\/chest.119.2.478"},{"key":"10.1160\/TH11-10-0690-125","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000163548.38396.E7"},{"key":"10.1160\/TH11-10-0690-126","doi-asserted-by":"publisher","DOI":"10.1111\/j.1538-7836.2006.01986.x"},{"key":"10.1160\/TH11-10-0690-127","doi-asserted-by":"crossref","first-page":"293","DOI":"10.7326\/0003-4819-150-5-200903030-00005","volume":"150","author":"Crowther","year":"2009","journal-title":"Ann Intern Med"},{"key":"10.1160\/TH11-10-0690-128","doi-asserted-by":"crossref","first-page":"251","DOI":"10.7326\/0003-4819-137-4-200208200-00009","volume":"137","author":"Crowther","year":"2002","journal-title":"Ann Intern Med"},{"key":"10.1160\/TH11-10-0690-129","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.163.20.2469"},{"key":"10.1160\/TH11-10-0690-130","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1160\/TH07-02-0086","volume":"98","author":"van","year":"2007","journal-title":"Thromb Haemost"},{"key":"10.1160\/TH11-10-0690-131","doi-asserted-by":"publisher","DOI":"10.4065\/82.1.82"},{"key":"10.1160\/TH11-10-0690-132","doi-asserted-by":"publisher","DOI":"10.1016\/j.thromres.2005.08.005"},{"key":"10.1160\/TH11-10-0690-133","doi-asserted-by":"publisher","DOI":"10.1111\/j.1538-7836.2008.02904.x"},{"key":"10.1160\/TH11-10-0690-134","doi-asserted-by":"publisher","DOI":"10.1097\/01.CCM.0000281468.94108.4B"},{"key":"10.1160\/TH11-10-0690-135","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2006.05.021"},{"key":"10.1160\/TH11-10-0690-136","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2008.03.067"},{"key":"10.1160\/TH11-10-0690-137","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2005.03.042"},{"key":"10.1160\/TH11-10-0690-138","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(09)61343-X"},{"key":"10.1160\/TH11-10-0690-139","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.110.976449"},{"key":"10.1160\/TH11-10-0690-140","doi-asserted-by":"publisher","DOI":"10.1160\/TH11-05-0358"},{"key":"10.1160\/TH11-10-0690-141","doi-asserted-by":"publisher","DOI":"10.1160\/TH09-09-0659"},{"key":"10.1160\/TH11-10-0690-142","doi-asserted-by":"publisher","DOI":"10.1160\/TH10-12-0808"},{"key":"10.1160\/TH11-10-0690-143","doi-asserted-by":"publisher","DOI":"10.1160\/TH10-05-0328"},{"key":"10.1160\/TH11-10-0690-144","doi-asserted-by":"publisher","DOI":"10.1160\/TH09-11-0758"},{"key":"10.1160\/TH11-10-0690-145","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.111.029017"},{"key":"10.1160\/TH11-10-0690-146","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8167.2011.02175.x."}],"container-title":["Thrombosis and Haemostasis"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1160\/TH11-10-0690.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,6,18]],"date-time":"2019-06-18T19:56:33Z","timestamp":1560887793000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1160\/TH11-10-0690"}},"subtitle":["Executive Summary of a Position Document from the European Heart Rhythm Association [EHRA], endorsed by the European Society of Cardiology [ESC] Working Group on Thrombosis"],"short-title":[],"issued":{"date-parts":[[2011]]},"references-count":146,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2017,11,27]]},"published-print":{"date-parts":[[2011]]}},"URL":"https:\/\/doi.org\/10.1160\/th11-10-0690","relation":{},"ISSN":["0340-6245","2567-689X"],"issn-type":[{"value":"0340-6245","type":"print"},{"value":"2567-689X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011]]}}}