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In this review, after a brief analysis of the potential molecular mechanisms by which the blood group influences haemostasis, we focus on the clinical implications of such interaction. Overall, the literature data document the close relationship between venous thromboembolism (VTE) and non-O blood type, which is associated with an approximately two-fold increased risk of venous thrombosis. A supra-additive effect on VTE risk is observed when an inherited thrombophilic condition is associated with non-O blood group. A weaker association exists between non-O blood type and arterial thrombosis, which needs to be further investigated.<\/jats:p>","DOI":"10.1160\/th14-05-0457","type":"journal-article","created":{"date-parts":[[2014,9,4]],"date-time":"2014-09-04T10:33:04Z","timestamp":1409826784000},"page":"1103-1109","source":"Crossref","is-referenced-by-count":91,"title":["ABO blood group and thrombotic vascular disease"],"prefix":"10.1160","volume":"112","author":[{"given":"Pier Mannuccio","family":"Mannucci","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Massimo","family":"Franchini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2017,11,17]]},"reference":[{"key":"10.1160\/TH14-05-0457-1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1537-2995.1961.tb00005.x"},{"key":"10.1160\/TH14-05-0457-2","doi-asserted-by":"crossref","first-page":"1545","DOI":"10.1515\/cclm-2013-0168","volume":"51","author":"Franchini","year":"2013","journal-title":"Clin Chem Lab Med"},{"key":"10.1160\/TH14-05-0457-3","doi-asserted-by":"crossref","first-page":"48","DOI":"10.21307\/immunohematology-2019-231","volume":"25","author":"Storry","year":"2009","journal-title":"Immunohematology"},{"key":"10.1160\/TH14-05-0457-4","doi-asserted-by":"publisher","DOI":"10.1016\/S0950-3536(05)80155-6"},{"key":"10.1160\/TH14-05-0457-5","doi-asserted-by":"publisher","DOI":"10.1046\/j.1537-2995.1998.381098440863.x"},{"key":"10.1160\/TH14-05-0457-6","doi-asserted-by":"publisher","DOI":"10.3109\/10408363.2012.708647"},{"key":"10.1160\/TH14-05-0457-7","first-page":"491","volume":"11","author":"Liumbruno","year":"2013","journal-title":"Blood Transfus"},{"key":"10.1160\/TH14-05-0457-8","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2010-01-261859"},{"key":"10.1160\/TH14-05-0457-9","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.1964.tb00698.x"},{"key":"10.1160\/TH14-05-0457-10","doi-asserted-by":"crossref","unstructured":"Moeller A, et al. 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