{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T19:46:01Z","timestamp":1791920761313,"version":"4.3.4"},"reference-count":0,"publisher":"Quintessence Publishing","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int J Oral Maxillofac Implants"],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:p>Purpose: Achieving predictable implant stability in low-density maxillary bone (D3\u2013D4) remains clinically challenging because reduced bone density is associated with greater early loss of stability and an increased risk of implant failure. Photobiomodulation (PBM) has been proposed to enhance osseointegration; however, clinical evidence regarding its effect on implant stability in low-density bone remains limited and inconsistent. The aim of this study is to evaluate the effect of 940-nm diode laser photobiomodulation (PBM) on implant stability during early healing in low-density maxillary bone (D3\u2013D4). Materials and Methods: This split-mouth, randomized controlled clinical trial included medically healthy adults who required bilateral maxillary implants. A total of 40 implants were placed in 10 participants using a guided flapless protocol. Test sites received 940-nm diode laser PBM immediately after implant placement and at 2-week intervals for 2 months, while contralateral sites served as controls. Implant stability was measured using resonance frequency analysis and expressed as implant stability quotient (ISQ) at baseline (T0), 2 months (T1), and 3 months (T2). Data was analyzed using linear mixed-effects model as primary analysis and two-way repeated-measures analysis of variance as supportive. Results: In the primary mixed-effects analysis, implant stability did not differ significantly between the PBM and control groups at baseline (estimated mean difference [PBM control], \u22122.45 ISQ; P = 0.341). At 2 months, PBM-treated implants demonstrated significantly higher estimated stability than control implants (mean difference, 6.30 ISQ; 95% CI, 1.21\u201311.39; P = 0.016). At 3 months, no significant between-group difference was observed (mean difference, 0.40 ISQ; P = 0.878). The linear mixed-effects model demonstrated a significant time \u00d7 treatment interaction (P = 0.042), indicating that implant-stability trajectories differed between the groups over time. The complete-case repeated-measures ANOVA yielded a consistent significant time \u00d7 treatment interaction (P = 0.007). No adverse effects related to PBM were observed. Conclusions: Photobiomodulation using a 940-nm diode laser enhanced early implant stability and reduced the magnitude of the stability dip in D3\u2013D4 maxillary bone without affecting final implant stability after 3 months. PBM may represent a safe adjunctive approach to support early osseointegration in low-density bone.<\/jats:p>","DOI":"10.11607\/jomi.11943","type":"journal-article","created":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T14:22:23Z","timestamp":1791469343000},"page":"1-34","source":"Crossref","is-referenced-by-count":0,"title":["Effect of Low-Level Laser Therapy on Stability of Dental Implants in D3 and D4 Bone Quality: A Split-Mouth Randomized Controlled Clinical Trial"],"prefix":"10.11607","author":[{"given":"Omer Ali","family":"Hama","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suha Nafea","family":"Aloosi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"4874","container-title":["The International Journal of Oral &amp; Maxillofacial Implants"],"original-title":[],"deposited":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T14:22:24Z","timestamp":1791469344000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.quintessence-publishing.com\/usa\/en\/article\/7120220\/the-international-journal-of-oral-maxillofacial-implants\/preprint\/effect-of-low-level-laser-therapy-on-stability-of-dental-implants-in-d3-and-d4-bone-quality-a-split-mouth-randomized-controlled-clinical-trial"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10]]},"references-count":0,"aliases":["10.11607\/prd.11943"],"URL":"https:\/\/doi.org\/10.11607\/jomi.11943","relation":{},"ISSN":["0882-2786"],"issn-type":[{"value":"0882-2786","type":"print"}],"subject":[],"published":{"date-parts":[[2026,10]]}}}