{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T08:52:47Z","timestamp":1789203167102,"version":"build-2803163510"},"reference-count":15,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"11","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Circulation"],"published-print":{"date-parts":[[1999,9,14]]},"abstract":"<jats:p>\n                    <jats:italic>Background<\/jats:italic>\n                    \u2014We treated paroxysmal recurrent atrial fibrillation (AF) with radiofrequency (RF) catheter ablation by creating long linear lesions in the atria. To achieve line continuity, a 3D electroanatomic nonfluoroscopic mapping system was used.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:italic>Methods and Results<\/jats:italic>\n                    \u2014In 27 patients with recurrent AF, a catheter incorporating a passive magnetic field sensor was navigated in both atria to construct a 3D activation map. RF energy was delivered to create continuous linear lesions: 3 lines (intercaval, isthmic, and anteroseptal) in the right atrium and a long line encircling the pulmonary veins in the left atrium. After RF application, the atria were remapped to validate completeness of the block lines, demonstrated by late activation of the areas circumscribed by the lines. The mean procedure duration was 312\u00b1103 minutes (range, 187 to 495), with mean fluoroscopy time of 107\u00b144 minutes (range, 32 to 185 minutes). No acute complications occurred, but 1 patient experienced early prolonged sinus pauses and received a pacemaker. During the first day, 17 patients (63%) had AF episodes, but at discharge, 25 patients were in sinus rhythm. After a follow-up of 6.0 to 15.3 months (average, 10.5\u00b13.0 months), 16 patients are asymptomatic, 3 have an almost complete disappearance of symptoms, 1 patient is improved, and 7 patients have their AF attacks unchanged.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:italic>Conclusions<\/jats:italic>\n                    \u2014Paroxysmal recurrent drug-refractory AF can be treated by RF catheter ablation. Creation of long continuous linear lesions necessary to compartmentalize the atria is facilitated by a nonfluoroscopic electroanatomic mapping system.\n                  <\/jats:p>","DOI":"10.1161\/01.cir.100.11.1203","type":"journal-article","created":{"date-parts":[[2012,6,11]],"date-time":"2012-06-11T20:42:29Z","timestamp":1339447349000},"page":"1203-1208","update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":246,"title":["Catheter Ablation of Paroxysmal Atrial Fibrillation Using a 3D Mapping System"],"prefix":"10.1161","volume":"100","author":[{"given":"Carlo","family":"Pappone","sequence":"first","affiliation":[{"name":"From the Cardiology Department, Hospital S. Raffaele, Milan, Italy (C.P., F.L., G.V., M.L.L., M.R., A.C., S.C.); the Cardiology Department, University of Messina, Messina, Italy (G.O., M.P.C.); the Cardiovascular System Laboratory, Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel (S.S., S.A.B.-H.); and the Allgemeines Krankenhaus St Georg, II Medizinische Abteilung, Hamburg, Germany (R.C.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giuseppe","family":"Oreto","sequence":"additional","affiliation":[{"name":"From the Cardiology Department, Hospital S. Raffaele, Milan, Italy (C.P., F.L., G.V., M.L.L., M.R., A.C., S.C.); the Cardiology Department, University of Messina, Messina, Italy (G.O., M.P.C.); the Cardiovascular System Laboratory, Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel (S.S., S.A.B.-H.); and the Allgemeines Krankenhaus St Georg, II Medizinische Abteilung, Hamburg, Germany (R.C.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Filippo","family":"Lamberti","sequence":"additional","affiliation":[{"name":"From the Cardiology Department, Hospital S. Raffaele, Milan, Italy (C.P., F.L., G.V., M.L.L., M.R., A.C., S.C.); the Cardiology Department, University of Messina, Messina, Italy (G.O., M.P.C.); the Cardiovascular System Laboratory, Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel (S.S., S.A.B.-H.); and the Allgemeines Krankenhaus St Georg, II Medizinische Abteilung, Hamburg, Germany (R.C.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriele","family":"Vicedomini","sequence":"additional","affiliation":[{"name":"From the Cardiology Department, Hospital S. Raffaele, Milan, Italy (C.P., F.L., G.V., M.L.L., M.R., A.C., S.C.); the Cardiology Department, University of Messina, Messina, Italy (G.O., M.P.C.); the Cardiovascular System Laboratory, Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel (S.S., S.A.B.-H.); and the Allgemeines Krankenhaus St Georg, II Medizinische Abteilung, Hamburg, Germany (R.C.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Luisa","family":"Loricchio","sequence":"additional","affiliation":[{"name":"From the Cardiology Department, Hospital S. Raffaele, Milan, Italy (C.P., F.L., G.V., M.L.L., M.R., A.C., S.C.); the Cardiology Department, University of Messina, Messina, Italy (G.O., M.P.C.); the Cardiovascular System Laboratory, Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel (S.S., S.A.B.-H.); and the Allgemeines Krankenhaus St Georg, II Medizinische Abteilung, Hamburg, Germany (R.C.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shlomo","family":"Shpun","sequence":"additional","affiliation":[{"name":"From the Cardiology Department, Hospital S. Raffaele, Milan, Italy (C.P., F.L., G.V., M.L.L., M.R., A.C., S.C.); the Cardiology Department, University of Messina, Messina, Italy (G.O., M.P.C.); the Cardiovascular System Laboratory, Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel (S.S., S.A.B.-H.); and the Allgemeines Krankenhaus St Georg, II Medizinische Abteilung, Hamburg, Germany (R.C.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariano","family":"Rillo","sequence":"additional","affiliation":[{"name":"From the Cardiology Department, Hospital S. Raffaele, Milan, Italy (C.P., F.L., G.V., M.L.L., M.R., A.C., S.C.); the Cardiology Department, University of Messina, Messina, Italy (G.O., M.P.C.); the Cardiovascular System Laboratory, Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel (S.S., S.A.B.-H.); and the Allgemeines Krankenhaus St Georg, II Medizinische Abteilung, Hamburg, Germany (R.C.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Pia","family":"Calabro\u0300","sequence":"additional","affiliation":[{"name":"From the Cardiology Department, Hospital S. Raffaele, Milan, Italy (C.P., F.L., G.V., M.L.L., M.R., A.C., S.C.); the Cardiology Department, University of Messina, Messina, Italy (G.O., M.P.C.); the Cardiovascular System Laboratory, Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel (S.S., S.A.B.-H.); and the Allgemeines Krankenhaus St Georg, II Medizinische Abteilung, Hamburg, Germany (R.C.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Conversano","sequence":"additional","affiliation":[{"name":"From the Cardiology Department, Hospital S. Raffaele, Milan, Italy (C.P., F.L., G.V., M.L.L., M.R., A.C., S.C.); the Cardiology Department, University of Messina, Messina, Italy (G.O., M.P.C.); the Cardiovascular System Laboratory, Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel (S.S., S.A.B.-H.); and the Allgemeines Krankenhaus St Georg, II Medizinische Abteilung, Hamburg, Germany (R.C.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shlomo A.","family":"Ben-Haim","sequence":"additional","affiliation":[{"name":"From the Cardiology Department, Hospital S. Raffaele, Milan, Italy (C.P., F.L., G.V., M.L.L., M.R., A.C., S.C.); the Cardiology Department, University of Messina, Messina, Italy (G.O., M.P.C.); the Cardiovascular System Laboratory, Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel (S.S., S.A.B.-H.); and the Allgemeines Krankenhaus St Georg, II Medizinische Abteilung, Hamburg, Germany (R.C.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Riccardo","family":"Cappato","sequence":"additional","affiliation":[{"name":"From the Cardiology Department, Hospital S. Raffaele, Milan, Italy (C.P., F.L., G.V., M.L.L., M.R., A.C., S.C.); the Cardiology Department, University of Messina, Messina, Italy (G.O., M.P.C.); the Cardiovascular System Laboratory, Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel (S.S., S.A.B.-H.); and the Allgemeines Krankenhaus St Georg, II Medizinische Abteilung, Hamburg, Germany (R.C.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sergio","family":"Chierchia","sequence":"additional","affiliation":[{"name":"From the Cardiology Department, Hospital S. Raffaele, Milan, Italy (C.P., F.L., G.V., M.L.L., M.R., A.C., S.C.); the Cardiology Department, University of Messina, Messina, Italy (G.O., M.P.C.); the Cardiovascular System Laboratory, Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel (S.S., S.A.B.-H.); and the Allgemeines Krankenhaus St Georg, II Medizinische Abteilung, Hamburg, Germany (R.C.)."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"e_1_3_1_1_2","first-page":"319","volume":"3","year":"1985","unstructured":"Kerr CR, Chung DC. Atrial fibrillation: fact, controversy and future. 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