{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T01:53:08Z","timestamp":1787017988421,"version":"build-2736575974"},"reference-count":19,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Circulation"],"published-print":{"date-parts":[[1999,7,13]]},"abstract":"<jats:p>\n                    <jats:italic>Background<\/jats:italic>\n                    \u2014Risks of coronary artery bypass graft surgery (CABG) or percutaneous transluminal coronary angioplasty (PTCA) may be different in the presence of peripheral vascular disease (PVD).\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:italic>Methods and Results<\/jats:italic>\n                    \u2014We analyzed outcomes of 550 patients with PVD enrolled in the Bypass Angioplasty Revascularization Investigation randomized trial and registry. Compared with 1770 patients without PVD, those with PVD were older and had a greater prevalence of medical comorbid conditions. No significant differences in coronary anatomy or PTCA success rates were found. The risk of any major complication (death, myocardial infarction, stroke, coma, or emergency revascularization) after PTCA was significantly higher among patients with PVD (11.7% versus 7.8%,\n                    <jats:italic>P<\/jats:italic>\n                    =0.027). In multivariate analysis, this represented a 50% increase in the odds of having any major complication (multivariate odds ratio, 1.5;\n                    <jats:italic>P<\/jats:italic>\n                    =0.032). Among patients undergoing CABG, the risk of major complications was found to be markedly higher for patients with PVD (12%) than those without (6.1%,\n                    <jats:italic>P<\/jats:italic>\n                    =0.003) even after controlling for baseline differences (multivariate odds ratio, 1.8;\n                    <jats:italic>P<\/jats:italic>\n                    =0.018). Major differences between the PTCA and CABG groups were related primarily to a higher risk of neurological complications in PVD patients who had CABG (multivariate odds ratio, 2.8;\n                    <jats:italic>P<\/jats:italic>\n                    &lt;0.001).\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:italic>Conclusions<\/jats:italic>\n                    \u2014We conclude that patients with PVD are at high risk for periprocedural complications after myocardial revascularization, in particular neurological events.\n                  <\/jats:p>","DOI":"10.1161\/01.cir.100.2.171","type":"journal-article","created":{"date-parts":[[2012,6,11]],"date-time":"2012-06-11T20:42:29Z","timestamp":1339447349000},"page":"171-177","update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":77,"title":["Increased Incidence of Periprocedural Complications Among Patients With Peripheral Vascular Disease Undergoing Myocardial Revascularization in the Bypass Angioplasty Revascularization Investigation"],"prefix":"10.1161","volume":"100","author":[{"given":"Charanjit S.","family":"Rihal","sequence":"first","affiliation":[{"name":"From the Mayo Clinic and Mayo Foundation (C.S.R., H.V.S., D.R.H.), Rochester, Minn; the University of Pittsburgh (K.S.-T., P.G.), Pittsburgh, Pa; New York Medical Center (N.M.K.), New York, NY; the Institute for Clinical and Experimental Medicine (R.J.), Prague, Czech Republic; and Duke Clinical Research Institute (M.A.S.), Durham, NC."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kim","family":"Sutton-Tyrrell","sequence":"additional","affiliation":[{"name":"From the Mayo Clinic and Mayo Foundation (C.S.R., H.V.S., D.R.H.), Rochester, Minn; the University of Pittsburgh (K.S.-T., P.G.), Pittsburgh, Pa; New York Medical Center (N.M.K.), New York, NY; the Institute for Clinical and Experimental Medicine (R.J.), Prague, Czech Republic; and Duke Clinical Research Institute (M.A.S.), Durham, NC."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ping","family":"Guo","sequence":"additional","affiliation":[{"name":"From the Mayo Clinic and Mayo Foundation (C.S.R., H.V.S., D.R.H.), Rochester, Minn; the University of Pittsburgh (K.S.-T., P.G.), Pittsburgh, Pa; New York Medical Center (N.M.K.), New York, NY; the Institute for Clinical and Experimental Medicine (R.J.), Prague, Czech Republic; and Duke Clinical Research Institute (M.A.S.), Durham, NC."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Norma M.","family":"Keller","sequence":"additional","affiliation":[{"name":"From the Mayo Clinic and Mayo Foundation (C.S.R., H.V.S., D.R.H.), Rochester, Minn; the University of Pittsburgh (K.S.-T., P.G.), Pittsburgh, Pa; New York Medical Center (N.M.K.), New York, NY; the Institute for Clinical and Experimental Medicine (R.J.), Prague, Czech Republic; and Duke Clinical Research Institute (M.A.S.), Durham, NC."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruzena","family":"Jandova","sequence":"additional","affiliation":[{"name":"From the Mayo Clinic and Mayo Foundation (C.S.R., H.V.S., D.R.H.), Rochester, Minn; the University of Pittsburgh (K.S.-T., P.G.), Pittsburgh, Pa; New York Medical Center (N.M.K.), New York, NY; the Institute for Clinical and Experimental Medicine (R.J.), Prague, Czech Republic; and Duke Clinical Research Institute (M.A.S.), Durham, NC."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary Ann","family":"Sellers","sequence":"additional","affiliation":[{"name":"From the Mayo Clinic and Mayo Foundation (C.S.R., H.V.S., D.R.H.), Rochester, Minn; the University of Pittsburgh (K.S.-T., P.G.), Pittsburgh, Pa; New York Medical Center (N.M.K.), New York, NY; the Institute for Clinical and Experimental Medicine (R.J.), Prague, Czech Republic; and Duke Clinical Research Institute (M.A.S.), Durham, NC."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hartzell V.","family":"Schaff","sequence":"additional","affiliation":[{"name":"From the Mayo Clinic and Mayo Foundation (C.S.R., H.V.S., D.R.H.), Rochester, Minn; the University of Pittsburgh (K.S.-T., P.G.), Pittsburgh, Pa; New York Medical Center (N.M.K.), New York, NY; the Institute for Clinical and Experimental Medicine (R.J.), Prague, Czech Republic; and Duke Clinical Research Institute (M.A.S.), Durham, NC."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"Jr","given":"David R.","family":"Holmes","sequence":"additional","affiliation":[{"name":"From the Mayo Clinic and Mayo Foundation (C.S.R., H.V.S., D.R.H.), Rochester, Minn; the University of Pittsburgh (K.S.-T., P.G.), Pittsburgh, Pa; New York Medical Center (N.M.K.), New York, NY; the Institute for Clinical and Experimental Medicine (R.J.), Prague, Czech Republic; and Duke Clinical Research Institute (M.A.S.), Durham, NC."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"e_1_3_1_1_2","unstructured":"Gersh BJ Califf RM Loop FD Akins CW Pryor DB Takaro TC. Coronary bypass surgery in chronic stable angina. Circulation. 1989;79(suppl I):I-46\u2013I-59."},{"key":"e_1_3_1_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(94)91963-1"},{"key":"e_1_3_1_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9149(97)00934-X"},{"key":"e_1_3_1_4_2","doi-asserted-by":"publisher","DOI":"10.1161\/circ.91.1.46"},{"key":"e_1_3_1_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0025-6196(12)60271-7"},{"key":"e_1_3_1_6_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1992.03480170070031"},{"key":"e_1_3_1_7_2","doi-asserted-by":"publisher","DOI":"10.1161\/circ.85.6.1591830"},{"key":"e_1_3_1_8_2","unstructured":"The BARI Protocol. Protocol for the Bypass Angioplasty Revascularization Investigation. Circulation. 1991;84(suppl V):V-1\u2013V-27."},{"key":"e_1_3_1_9_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199607253350401"},{"key":"e_1_3_1_10_2","doi-asserted-by":"publisher","DOI":"10.1161\/circ.94.7.1561"},{"key":"e_1_3_1_11_2","doi-asserted-by":"publisher","DOI":"10.3949\/ccjm.54.1.15"},{"key":"e_1_3_1_12_2","doi-asserted-by":"publisher","DOI":"10.1161\/str.18.4.3496690"},{"key":"e_1_3_1_13_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199612193352501"},{"key":"e_1_3_1_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5223(19)34874-3"},{"key":"e_1_3_1_15_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-110-11-859"},{"key":"e_1_3_1_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/0735-1097(95)00602-8"},{"key":"e_1_3_1_17_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-124-8-199604150-00010"},{"key":"e_1_3_1_18_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1995.03520480039037"},{"key":"e_1_3_1_19_2","first-page":"661","volume":"79","year":"1994","unstructured":"Fleisher LA, Skolnick ED, Holroyd KJ, Lehmann HP. Coronary artery revascularization before abdominal aortic aneurysm surgery: a decision analytic approach. Anesth Analg. 1994;79:661\u2013669.In the Bypass Angioplasty Revascularization Investigation study, the risk of any major complication (death, myocardial infarction, stroke, coma, or emergency revascularization) after PTCA was higher among 316 patients with peripheral vascular disease (PVD) than in 1770 without PVD (11.7% versus 7.8%, P=0.027). After CABG, the risk of major complications was higher among 234 patients with PVD than 1271 without PVD (12.0% versus 6.1%, P=0.03), especially neurological complications (4.7% versus 1.2%, P=0.001). In multivariate analysis, PVD was a significant correlate of complications after either PTCA or CABG. We conclude that patients with PVD are at high risk for periprocedural complications after myocardial revascularization.","journal-title":"Anesth Analg"}],"container-title":["Circulation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ahajournals.org\/doi\/full\/10.1161\/01.CIR.100.2.171","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,12]],"date-time":"2024-05-12T08:57:55Z","timestamp":1715504275000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ahajournals.org\/doi\/10.1161\/01.CIR.100.2.171"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1999,7,13]]},"references-count":19,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1999,7,13]]}},"alternative-id":["10.1161\/01.CIR.100.2.171"],"URL":"https:\/\/doi.org\/10.1161\/01.cir.100.2.171","relation":{},"ISSN":["0009-7322","1524-4539"],"issn-type":[{"value":"0009-7322","type":"print"},{"value":"1524-4539","type":"electronic"}],"subject":[],"published":{"date-parts":[[1999,7,13]]},"assertion":[{"value":"1998-05-28","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"1999-04-22","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"1999-07-13","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}