{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T16:28:10Z","timestamp":1791390490180,"version":"4.3.3"},"reference-count":28,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"21","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Circulation"],"published-print":{"date-parts":[[1999,11,23]]},"abstract":"<jats:p>\n            <jats:italic>Background<\/jats:italic>\n            \u2014The surgical approach to aortic root aneurysm and\/or dissection remains controversial. The use of valve-sparing operations, which are thought to have many advantages, is increasing. We hypothesized that the particular technique and type of surgery could influence valve motion characteristics and function. Therefore, we studied the instantaneous opening and closing characteristics of the aortic valve after the main 2 types of valve-sparing surgery.\n          <\/jats:p>\n          <jats:p>\n            <jats:italic>Methods and Results<\/jats:italic>\n            \u2014In 20 patients (10 with tube replacement of the aortic root, group A; and 10 with separate replacement of the sinuses of Valsalva, group B) and 10 controls (group C), transthoracic and transesophageal studies on aortic valve dynamics were performed. Three distinct phases of aortic valve motion were identified. They were as follows: (1) a rapid opening, with a velocity of 20.9\u00b14.2 cm\/s in group C, 27.1\u00b110.9 cm\/s in group B (\n            <jats:italic>P<\/jats:italic>\n            =NS), and 58.3\u00b118.4 cm\/s in group A (group A versus group C,\n            <jats:italic>P<\/jats:italic>\n            &lt;0.001; group A versus group B,\n            <jats:italic>P<\/jats:italic>\n            =0.001); (2) a slow systolic closure, with 12.5\u00b16.6% and 10.8\u00b12.2% of maximal opening in groups C and B, respectively (\n            <jats:italic>P<\/jats:italic>\n            =NS), and 3.8\u00b11.6% in group A (group A versus group C,\n            <jats:italic>P<\/jats:italic>\n            =0.001; group A versus group B,\n            <jats:italic>P<\/jats:italic>\n            &lt;0.001); and (3) a rapid closing movement, with a velocity of 26.3\u00b15.6 cm\/s in group C, 32.4\u00b111.4 cm\/s in group B (\n            <jats:italic>P<\/jats:italic>\n            =NS), and 21.8\u00b13.5 cm\/s in group A (group A versus group C,\n            <jats:italic>P<\/jats:italic>\n            =NS; group A versus group B,\n            <jats:italic>P<\/jats:italic>\n            =0.008). The pressure strain of the elastic modulus was different in groups C and B only at the commissures (682\u00b1145 g\/cm\n            <jats:sup>2<\/jats:sup>\n            versus 1896\u00b1726 g\/cm\n            <jats:sup>2<\/jats:sup>\n            , respectively;\n            <jats:italic>P<\/jats:italic>\n            &lt;0.001). At all root levels, the distensibility was reduced in group A (\n            <jats:italic>P<\/jats:italic>\n            &lt;0.001). Systolic contact of aortic cusps and wall occurred only in group A.\n          <\/jats:p>\n          <jats:p>\n            <jats:italic>Conclusions<\/jats:italic>\n            \u2014Near-normal opening and closing characteristics can be achieved by a technique that preserves the shape and independent mobility of the sinuses of Valsalva.\n          <\/jats:p>","DOI":"10.1161\/01.cir.100.21.2153","type":"journal-article","created":{"date-parts":[[2012,6,12]],"date-time":"2012-06-12T00:42:29Z","timestamp":1339461749000},"page":"2153-2160","update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":259,"title":["Opening and Closing Characteristics of the Aortic Valve After Different Types of Valve-Preserving Surgery"],"prefix":"10.1161","volume":"100","author":[{"given":"Rainer G.","family":"Leyh","sequence":"first","affiliation":[{"name":"From the Departments of Cardiac Surgery, Medical University of Lu\u0308beck, Lu\u0308beck, Germany (R.G.L., C.S., H.-H.S.), and the National Heart and Lung Institute at the Imperial College of Science, Technology, and Medicine, London, UK (M.H.Y.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudia","family":"Schmidtke","sequence":"additional","affiliation":[{"name":"From the Departments of Cardiac Surgery, Medical University of Lu\u0308beck, Lu\u0308beck, Germany (R.G.L., C.S., H.-H.S.), and the National Heart and Lung Institute at the Imperial College of Science, Technology, and Medicine, London, UK (M.H.Y.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hans-Hinrich","family":"Sievers","sequence":"additional","affiliation":[{"name":"From the Departments of Cardiac Surgery, Medical University of Lu\u0308beck, Lu\u0308beck, Germany (R.G.L., C.S., H.-H.S.), and the National Heart and Lung Institute at the Imperial College of Science, Technology, and Medicine, London, UK (M.H.Y.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Magdi H.","family":"Yacoub","sequence":"additional","affiliation":[{"name":"From the Departments of Cardiac Surgery, Medical University of Lu\u0308beck, Lu\u0308beck, Germany (R.G.L., C.S., H.-H.S.), and the National Heart and Lung Institute at the Imperial College of Science, Technology, and Medicine, London, UK (M.H.Y.)."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"e_1_3_2_1_2","doi-asserted-by":"publisher","DOI":"10.1136\/thx.23.4.338"},{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5223(19)34835-4"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-199109000-00013"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1010-7940(96)80289-2"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5223(19)38476-4"},{"key":"e_1_3_2_6_2","first-page":"302","volume":"49","year":"1983","unstructured":"Fagan A, Pillai R, Radley-Smith R, Yacoub MH. 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