{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T07:31:24Z","timestamp":1787729484588,"version":"build-2784847793"},"reference-count":38,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"5","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Circulation"],"published-print":{"date-parts":[[2000,8]]},"abstract":"<jats:p>\n            <jats:italic>Background<\/jats:italic>\n            \u2014The width of the vena contracta (VC-W), the smallest area of regurgitant flow, reflects the degree of valvular regurgitation and is measurable by color Doppler imaging, but this method has not been validated in aortic regurgitation (AR).\n          <\/jats:p>\n          <jats:p>\n            <jats:italic>Methods and Results<\/jats:italic>\n            \u2014We prospectively examined 79 patients with isolated AR and 80 patients without regurgitation. The VC-W was measured from the long-axis parasternal view and compared with 2 simultaneous reference methods (quantitative Doppler and 2D echocardiography). In patients without regurgitation, the agreement between methods was excellent. In patients with AR, good correlations (all\n            <jats:italic>P<\/jats:italic>\n            &lt;0.0001) were obtained between VC-W and effective regurgitant orifice (ERO) area and regurgitant volume recorded by quantitative Doppler (\n            <jats:italic>r<\/jats:italic>\n            =0.89 and 0.90, respectively) and 2D echocardiographic (\n            <jats:italic>r<\/jats:italic>\n            =0.90 and 0.89, respectively) methods. These correlations were similar with eccentric or central jets (all\n            <jats:italic>P<\/jats:italic>\n            &gt;0.60). The other methods used showed good correlations of VC-W with aortographic grading of AR (n=8,\n            <jats:italic>r<\/jats:italic>\n            =0.82,\n            <jats:italic>P<\/jats:italic>\n            =0.01), with the proximal flow convergence method (n=53,\n            <jats:italic>r<\/jats:italic>\n            =0.85,\n            <jats:italic>P<\/jats:italic>\n            &lt;0.0001), and with left ventricular end-diastolic volume (\n            <jats:italic>r<\/jats:italic>\n            =0.81,\n            <jats:italic>P<\/jats:italic>\n            &lt;0.0001). Sensitivity and specificity of VC-W \u22656 mm for diagnosing severe AR (ERO \u226530 mm\n            <jats:sup>2<\/jats:sup>\n            ) were 95% and 90%, respectively.\n          <\/jats:p>\n          <jats:p>\n            <jats:italic>Conclusions<\/jats:italic>\n            \u2014For assessment of the degree of AR, VC-W shows good correlations with simultaneous quantitative measures (regardless of jet direction), shows good correlations with other methods of assessment of AR, and provides a high diagnostic value for severe AR. VC-W is a simple, reliable method that can be used clinically as part of comprehensive Doppler echocardiographic assessment of AR.\n          <\/jats:p>","DOI":"10.1161\/01.cir.102.5.558","type":"journal-article","created":{"date-parts":[[2012,6,12]],"date-time":"2012-06-12T00:42:29Z","timestamp":1339461749000},"page":"558-564","update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":122,"title":["Assessment of Severity of Aortic Regurgitation Using the Width of the Vena Contracta"],"prefix":"10.1161","volume":"102","author":[{"given":"Christophe M.","family":"Tribouilloy","sequence":"first","affiliation":[{"name":"From the Division of Cardiovascular Diseases and Internal Medicine (C.M.T., M.E.-S., J.B.S., A.J.T.) and the Section of Biostatistics (K.R.B.), Mayo Clinic and Mayo Foundation, Rochester, Minn."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maurice","family":"Enriquez-Sarano","sequence":"additional","affiliation":[{"name":"From the Division of Cardiovascular Diseases and Internal Medicine (C.M.T., M.E.-S., J.B.S., A.J.T.) and the Section of Biostatistics (K.R.B.), Mayo Clinic and Mayo Foundation, Rochester, Minn."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kent R.","family":"Bailey","sequence":"additional","affiliation":[{"name":"From the Division of Cardiovascular Diseases and Internal Medicine (C.M.T., M.E.-S., J.B.S., A.J.T.) and the Section of Biostatistics (K.R.B.), Mayo Clinic and Mayo Foundation, Rochester, Minn."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James B.","family":"Seward","sequence":"additional","affiliation":[{"name":"From the Division of Cardiovascular Diseases and Internal Medicine (C.M.T., M.E.-S., J.B.S., A.J.T.) and the Section of Biostatistics (K.R.B.), Mayo Clinic and Mayo Foundation, Rochester, Minn."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A. Jamil","family":"Tajik","sequence":"additional","affiliation":[{"name":"From the Division of Cardiovascular Diseases and Internal Medicine (C.M.T., M.E.-S., J.B.S., A.J.T.) and the Section of Biostatistics (K.R.B.), Mayo Clinic and Mayo Foundation, Rochester, Minn."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"e_1_3_2_1_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.84.4.1625"},{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/0735-1097(94)90432-4"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1161\/circ.87.3.8443904"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.65.1.37"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(86)80306-0"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(87)80254-1"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.eurheartj.a062514"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.eurheartj.a059901"},{"key":"e_1_3_2_9_2","doi-asserted-by":"crossref","unstructured":"Diebold B Touati R Delouche A et al. 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