{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T04:58:04Z","timestamp":1761541084426},"reference-count":15,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"11","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Circulation"],"published-print":{"date-parts":[[2001,3,20]]},"abstract":"<jats:p>\n            <jats:italic>Background<\/jats:italic>\n            \u2014In this retrospective study, \u2248440 patients received mitral valve replacements with the St Jude Medical prothesis. The last patient was operated on 10 years before the beginning of the follow-up. The extended follow-up was 19 years.\n          <\/jats:p>\n          <jats:p>\n            <jats:italic>Methods and Results<\/jats:italic>\n            \u2014Four hundred forty patients (sex ratio, 1.32 [men to women]; age, 60\u00b111.4 years; age range, 7 to 75 years) were operated on from 1979 to 1987. All patients underwent isolated mitral valve replacement. Tricuspid plasty was the only associated procedure. The follow-up at 19 years was 98% complete. The overall actuarial survival rate was 63\u00b13.3% at 19 years, and the actuarial survival rate (only valve related) was 83\u00b12.7%. The operative mortality rate (0 to 30 days) was 4.09%. We found that 89.4% of the patients alive at 19 years were in NYHA class I\/II. Multivariate analysis showed that age and sex were significantly correlated with valve-related mortality and that age, sex, NYHA class, and atrial fibrillation were significantly correlated with overall mortality. The linearized rates (percent patient-years) of thromboembolism, thrombosis, and hemorrhage were 0.69, 0.2, and 1, respectively. At 19 years, freedom from endocarditis and reoperation was 98.6\u00b11% and 90\u00b13%, respectively.\n          <\/jats:p>\n          <jats:p>\n            <jats:italic>Conclusions<\/jats:italic>\n            \u2014In this study, the very-long-term results confirm the excellent durability of the St Jude Medical prosthesis in the mitral position and show the difficulty of adjusting the anticoagulation protocol, even after long-term treatment.\n          <\/jats:p>","DOI":"10.1161\/01.cir.103.11.1542","type":"journal-article","created":{"date-parts":[[2012,6,12]],"date-time":"2012-06-12T00:09:32Z","timestamp":1339459772000},"page":"1542-1545","update-policy":"http:\/\/dx.doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":43,"title":["Isolated Mitral Valve Replacement With St Jude Medical Prosthesis"],"prefix":"10.1161","volume":"103","author":[{"given":"J. P.","family":"Remadi","sequence":"first","affiliation":[{"name":"From the Cardiovascular Surgery Unit and Department of Anesthesiology, G. and R. Lae\u0308nnec University Hospital, Nantes, France."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"O.","family":"Baron","sequence":"additional","affiliation":[{"name":"From the Cardiovascular Surgery Unit and Department of Anesthesiology, G. and R. Lae\u0308nnec University Hospital, Nantes, France."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Roussel","sequence":"additional","affiliation":[{"name":"From the Cardiovascular Surgery Unit and Department of Anesthesiology, G. and R. Lae\u0308nnec University Hospital, Nantes, France."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Bizouarn","sequence":"additional","affiliation":[{"name":"From the Cardiovascular Surgery Unit and Department of Anesthesiology, G. and R. Lae\u0308nnec University Hospital, Nantes, France."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Al","family":"Habasch","sequence":"additional","affiliation":[{"name":"From the Cardiovascular Surgery Unit and Department of Anesthesiology, G. and R. Lae\u0308nnec University Hospital, Nantes, France."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Despins","sequence":"additional","affiliation":[{"name":"From the Cardiovascular Surgery Unit and Department of Anesthesiology, G. and R. Lae\u0308nnec University Hospital, Nantes, France."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. L.","family":"Michaud","sequence":"additional","affiliation":[{"name":"From the Cardiovascular Surgery Unit and Department of Anesthesiology, G. and R. Lae\u0308nnec University Hospital, Nantes, France."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Duveau","sequence":"additional","affiliation":[{"name":"From the Cardiovascular Surgery Unit and Department of Anesthesiology, G. and R. Lae\u0308nnec University Hospital, Nantes, France."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"e_1_3_1_1_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0003-4975(98)00467-6"},{"key":"e_1_3_1_2_2","doi-asserted-by":"crossref","unstructured":"Edmunds LH Jr Clark RE Cohn LH et al. Guidelines for reporting morbidity and mortality after cardiac valvular operations. Ann Thorac Surg.1996;62:932\u2013935.","DOI":"10.1016\/S0003-4975(96)00531-0"},{"key":"e_1_3_1_3_2","unstructured":"Gohlke-B\u00e2rwolf C Acar J Burckhardt D et al. 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