{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T14:51:33Z","timestamp":1787496693109,"version":"build-2736575974"},"reference-count":0,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"6","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Circulation"],"published-print":{"date-parts":[[1962,6]]},"abstract":"<jats:p>The clinical, physiologic, and anatomic features of a special group of cases of total anomalous, pulmonary venous connection are reviewed.<\/jats:p>\n                  <jats:p>The occurrence of severe pulmonary venous obstruction in total anomalous pulmonary venous connection produces a characteristic syndrome:<\/jats:p>\n                  <jats:p>1. Very early onset of dyspnea and heart failure.<\/jats:p>\n                  <jats:p>2. Considerably more cyanosis than the usual case without obstruction.<\/jats:p>\n                  <jats:p>3. Typical x-ray showing diffuse hazy lung fields with reticulated appearance without cardiac enlargement.<\/jats:p>\n                  <jats:p>\n                    4. Electrocardiographic evidence of severe right ventricular hypertrophy with a tall R or qR pattern in lead V\n                    <jats:sub>1<\/jats:sub>\n                    and reversal of the R\/S ratio over the precordium.\n                  <\/jats:p>\n                  <jats:p>5. Physiologic findings of practically normal pulmonary flow, right ventricular and pulmonary arterial pressures greater than systemic, and a marked gradient between the pulmonary arterial \"wedge\" and right atrial pressures.<\/jats:p>\n                  <jats:p>6. Rapid deterioration and death in the first weeks or months of life.<\/jats:p>","DOI":"10.1161\/01.cir.25.6.916","type":"journal-article","created":{"date-parts":[[2012,6,11]],"date-time":"2012-06-11T19:27:25Z","timestamp":1339442845000},"page":"916-928","update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":60,"title":["Total Anomalous Pulmonary Venous Connection with Severe Pulmonary Venous Obstruction"],"prefix":"10.1161","volume":"25","author":[{"given":"ALOIS R.","family":"HASTREITER","sequence":"first","affiliation":[{"name":"From the Division of Cardiology, The Children's Memorial Hospital, and the Department of Pediatrics, Northwestern University Medical School, Chicago, Illinois."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"MILTON H.","family":"PAUL","sequence":"additional","affiliation":[{"name":"From the Division of Cardiology, The Children's Memorial Hospital, and the Department of Pediatrics, Northwestern University Medical School, Chicago, Illinois."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"MARIAN E.","family":"MOLTHAN","sequence":"additional","affiliation":[{"name":"From the Division of Cardiology, The Children's Memorial Hospital, and the Department of Pediatrics, Northwestern University Medical School, Chicago, Illinois."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"ROBERT A.","family":"MILLER","sequence":"additional","affiliation":[{"name":"From the Division of Cardiology, The Children's Memorial Hospital, and the Department of Pediatrics, Northwestern University Medical School, Chicago, Illinois."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","container-title":["Circulation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ahajournals.org\/doi\/pdf\/10.1161\/01.CIR.25.6.916","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,12]],"date-time":"2024-05-12T10:11:00Z","timestamp":1715508660000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ahajournals.org\/doi\/10.1161\/01.CIR.25.6.916"}},"subtitle":["A Clinical Entity"],"short-title":[],"issued":{"date-parts":[[1962,6]]},"references-count":0,"journal-issue":{"issue":"6","published-print":{"date-parts":[[1962,6]]}},"alternative-id":["10.1161\/01.CIR.25.6.916"],"URL":"https:\/\/doi.org\/10.1161\/01.cir.25.6.916","relation":{},"ISSN":["0009-7322","1524-4539"],"issn-type":[{"value":"0009-7322","type":"print"},{"value":"1524-4539","type":"electronic"}],"subject":[],"published":{"date-parts":[[1962,6]]},"assertion":[{"value":"1962-06-01","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}