{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,10]],"date-time":"2025-09-10T22:44:10Z","timestamp":1757544250859},"reference-count":0,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"5","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Circulation"],"published-print":{"date-parts":[[1971,5]]},"abstract":"<jats:p>\n            Flow-directed catheters recorded serial changes in mean pulmonary artery pressure (PA) every 4 to 6 hours in 25 patients during the first 4 or 5 days following acute myocardial infarction. On the basis of the PA on admission, patients were divided into three groups. Patients in group 1 had normal PA (10-20 mm Hg) and maintained a stroke volume index (SVI)&gt;35 ml\/min\/m\n            <jats:sup>2<\/jats:sup>\n            , a pulmonary artery oxygen saturation (MVSO\n            <jats:sub>2<\/jats:sub>\n            )&gt;70%, and a normal cardiac index, arterial oxygen saturation,\n            <jats:italic>p<\/jats:italic>\n            H, and P\n            <jats:sub>\n              CO\n              <jats:sub>CO2<\/jats:sub>\n            <\/jats:sub>\n            . They developed only minor arrhythmias, no heart failure, and none died. Group 3 consisted of one patient with abnormally low PA (&lt;10 mm Hg) who was hypovolemic. Group 2, those patients with elevated PA (&gt;20 mm Hg) who maintained this elevation over the first 48 hours of monitoring, or showed progressive elevation prior to this, had SVI&lt;35 ml\/min\/m\n            <jats:sup>2<\/jats:sup>\n            , MVSO\n            <jats:sub>2<\/jats:sub>\n            &lt;70%, cardiac index&lt;3 liters\/min\/m\n            <jats:sup>2<\/jats:sup>\n            , arterial desaturation, and respiratory alkalosis. They demonstrated clinical evidence of heart failure, had major arrhythmias, and 25% died. Three patients with elevated PA on admission spontaneously returned this pressure to normal over the first 48 hours of monitoring. Each of these patients maintained normal hemodynamics and had a good prognosis. PA was always elevated prior to the usual clinical signs of left ventricular failure. We conclude that PA provides a reliable early objective measure of left ventricular failure and is, therefore, an excellent guide to therapy.\n          <\/jats:p>","DOI":"10.1161\/01.cir.43.5.655","type":"journal-article","created":{"date-parts":[[2012,6,11]],"date-time":"2012-06-11T23:56:43Z","timestamp":1339459003000},"page":"655-666","update-policy":"http:\/\/dx.doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":27,"title":["The Value of Monitoring Pulmonary Artery Pressure for Early Detection of Left Ventricular Failure Following Myocardial Infarction"],"prefix":"10.1161","volume":"43","author":[{"given":"BARRY D.","family":"RUTHERFORD","sequence":"first","affiliation":[{"name":"From the Mayo Graduate School of Medicine (University of Minnesota) and the Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic and Mayo Foundation, Rochester, Minnesota 55901."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"WILLIAM D.","family":"MCCANN","sequence":"additional","affiliation":[{"name":"From the Mayo Graduate School of Medicine (University of Minnesota) and the Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic and Mayo Foundation, Rochester, Minnesota 55901."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T. PAUL B.","family":"O'DONOVAN","sequence":"additional","affiliation":[{"name":"From the Mayo Graduate School of Medicine (University of Minnesota) and the Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic and Mayo Foundation, Rochester, Minnesota 55901."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","container-title":["Circulation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ahajournals.org\/doi\/pdf\/10.1161\/01.CIR.43.5.655","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,12]],"date-time":"2024-05-12T14:16:22Z","timestamp":1715523382000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ahajournals.org\/doi\/10.1161\/01.CIR.43.5.655"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1971,5]]},"references-count":0,"journal-issue":{"issue":"5","published-print":{"date-parts":[[1971,5]]}},"alternative-id":["10.1161\/01.CIR.43.5.655"],"URL":"https:\/\/doi.org\/10.1161\/01.cir.43.5.655","relation":{},"ISSN":["0009-7322","1524-4539"],"issn-type":[{"value":"0009-7322","type":"print"},{"value":"1524-4539","type":"electronic"}],"subject":[],"published":{"date-parts":[[1971,5]]},"assertion":[{"value":"1970-09-25","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"1971-02-04","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"1971-05-01","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}