{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T15:37:49Z","timestamp":1758814669303},"reference-count":0,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Circulation"],"published-print":{"date-parts":[[1973,2]]},"abstract":"<jats:p>\n            Bedside catheterization permitted 56 simultaneous measurements of left ventricular end-diastolic pressure (LVEDP) and pulmonary artery end-diastolic pressure (PAEDP) in 25 patients in shock. Measurements were made over a wide range of heart rates (60-160 beats\/min), arterial oxygen tension (P\n            <jats:sub>\n              o\n              <jats:sub>o2<\/jats:sub>\n            <\/jats:sub>\n            ; 33-562 mm Hg), stroke volumes (9-105 ml), and systolic arterial pressures (65-250 mm Hg), and before and during various therapeutic interventions. There was good correlation between PAEDP and LVEDP (r = +0.85) and PAEDP and left ventricular pre-a pressure (r = +0.82). In 16 patients breathing room air, mean arterial P\n            <jats:sub>\n              o\n              <jats:sub>o2<\/jats:sub>\n            <\/jats:sub>\n            was 58 \u00b1 15 mm Hg and rose significantly to 282 \u00b1 16 mm Hg after breathing oxygen (P&lt;0.01), but there was no significant change in the correlation between PAEDP and LVEDP before (r = +0.80) or during oxygen breathing (r = +0.80). Similarly, in seven patients treated with inotropic agents there was excellent correlation between PAEDP and LVEDP before (r = +0.96) and during inotropic therapy (r = +0.86). A PAEDP in excess of 15 mm Hg nearly always reflected increased LVEDP while a PAEDP less than 10 mm Hg was always associated with normal LVEDP. Thus in our patients with shock PAEDP represented a good estimate of LVEDP during a variety of therapeutic interventions and therefore represents a useful tool in guiding the therapy of patients in shock.\n          <\/jats:p>","DOI":"10.1161\/01.cir.47.2.317","type":"journal-article","created":{"date-parts":[[2012,6,11]],"date-time":"2012-06-11T23:56:43Z","timestamp":1339459003000},"page":"317-324","update-policy":"http:\/\/dx.doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":27,"title":["Relationship between Pulmonary Artery End-Diastolic Pressure and Left Ventricular Filling Pressure in Patients in Shock"],"prefix":"10.1161","volume":"47","author":[{"given":"MELVIN","family":"SCHEINMAN","sequence":"first","affiliation":[{"name":"From the Cardiopulmonary Laboratory and Medical Services, San Francisco General Hospital, and the Department of Medicine and the Cardiovascular Research Institute, University of California, San Francisco."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G. THOMAS","family":"EVANS","sequence":"additional","affiliation":[{"name":"From the Cardiopulmonary Laboratory and Medical Services, San Francisco General Hospital, and the Department of Medicine and the Cardiovascular Research Institute, University of California, San Francisco."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"ALAN","family":"WEISS","sequence":"additional","affiliation":[{"name":"From the Cardiopulmonary Laboratory and Medical Services, San Francisco General Hospital, and the Department of Medicine and the Cardiovascular Research Institute, University of California, San Francisco."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"ELLIOT","family":"RAPAPORT","sequence":"additional","affiliation":[{"name":"From the Cardiopulmonary Laboratory and Medical Services, San Francisco General Hospital, and the Department of Medicine and the Cardiovascular Research Institute, University of California, San Francisco."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","container-title":["Circulation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ahajournals.org\/doi\/pdf\/10.1161\/01.CIR.47.2.317","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,12]],"date-time":"2024-05-12T14:05:52Z","timestamp":1715522752000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ahajournals.org\/doi\/10.1161\/01.CIR.47.2.317"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1973,2]]},"references-count":0,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1973,2]]}},"alternative-id":["10.1161\/01.CIR.47.2.317"],"URL":"https:\/\/doi.org\/10.1161\/01.cir.47.2.317","relation":{},"ISSN":["0009-7322","1524-4539"],"issn-type":[{"value":"0009-7322","type":"print"},{"value":"1524-4539","type":"electronic"}],"subject":[],"published":{"date-parts":[[1973,2]]},"assertion":[{"value":"1972-06-26","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"1972-10-12","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"1973-02-01","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}