{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,9,5]],"date-time":"2024-09-05T00:38:07Z","timestamp":1725496687057},"reference-count":0,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Circulation"],"published-print":{"date-parts":[[1973,3]]},"abstract":"<jats:p>Thirty-six hearts were studied in which all valves were involved in a dysplastic process. This consisted of an increase in spongiosa with vacuolar and lacunar degeneration, and a distinct lack of elastic tissue in the proximalis and in the spongiosa. This process was similar to, but more marked than that seen in a case of a single dysplastic valve as in bicuspid aortic valve. It was completely different than that seen in hemodynamic change. These cases clinically were often associated with trisomy 18 or trisomy 13-15, and called congenital polyvalvular disease. This disease may bear some relationship to Marfan's disease and the \"floppy valve\".<\/jats:p>","DOI":"10.1161\/01.cir.47.3.575","type":"journal-article","created":{"date-parts":[[2012,6,11]],"date-time":"2012-06-11T23:56:43Z","timestamp":1339459003000},"page":"575-586","update-policy":"http:\/\/dx.doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":46,"title":["Congenital Polyvalvular Disease"],"prefix":"10.1161","volume":"47","author":[{"given":"SAROJA","family":"BHARATI","sequence":"first","affiliation":[{"name":"From the Congenital Heart Disease Research and Training Center, Hektoen Institute for Medical Research; the Departments of Pathology, Northwestern University Medical School; Pritzker School of Medicine, University of Chicago; Abraham Lincoln School of Medicine, University of Illinois; the Chicago Medical School, University of Health Sciences; and Loyola University, Stritch School of Medicine, Chicago, Illinois."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"MAURICE","family":"LEV","sequence":"additional","affiliation":[{"name":"From the Congenital Heart Disease Research and Training Center, Hektoen Institute for Medical Research; the Departments of Pathology, Northwestern University Medical School; Pritzker School of Medicine, University of Chicago; Abraham Lincoln School of Medicine, University of Illinois; the Chicago Medical School, University of Health Sciences; and Loyola University, Stritch School of Medicine, Chicago, Illinois."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","container-title":["Circulation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ahajournals.org\/doi\/pdf\/10.1161\/01.CIR.47.3.575","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,12]],"date-time":"2024-05-12T14:05:54Z","timestamp":1715522754000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ahajournals.org\/doi\/10.1161\/01.CIR.47.3.575"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1973,3]]},"references-count":0,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1973,3]]}},"alternative-id":["10.1161\/01.CIR.47.3.575"],"URL":"https:\/\/doi.org\/10.1161\/01.cir.47.3.575","relation":{},"ISSN":["0009-7322","1524-4539"],"issn-type":[{"value":"0009-7322","type":"print"},{"value":"1524-4539","type":"electronic"}],"subject":[],"published":{"date-parts":[[1973,3]]},"assertion":[{"value":"1972-08-10","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"1972-10-26","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"1973-03-01","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}