{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,16]],"date-time":"2026-04-16T06:07:56Z","timestamp":1776319676689,"version":"3.50.1"},"reference-count":0,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Circulation"],"published-print":{"date-parts":[[1979,2]]},"abstract":"<jats:p>Two-dimensional echocardiography (2-D echo) was used with peripherally injected contrast material to detect interatrial shunts in 33 patients. Group 1 consisted of 11 patients having classic clinical findings of atrial septal defect. Group 2 consisted of 12 patients with problems requiring that atrial shunting be excluded. Group 3 (control group) consisted of 10 patients undergoing cardiac catheterization for chest pain. Confirmation of the 2-D echo findings was provided by cardiac catheterization in 32 patients and postmortem examination in one. Right-to-left atrial shunts were detected in all 11 patients in group 1, although seven had no right-to-left shunt calculable by oximetry. Four patients in Group 2 had right-to-left atrial shunts. None of the patients in Group 3 had atrial shunts. In the 15 patients with atrial shunts, the degree of right-to-left shunting could be qualitatively assessed as small, moderate, or large. There were no false-negative or false-positive results by contrast 2-D echo.<\/jats:p>","DOI":"10.1161\/01.cir.59.2.379","type":"journal-article","created":{"date-parts":[[2012,6,11]],"date-time":"2012-06-11T23:57:40Z","timestamp":1339459060000},"page":"379-384","update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":134,"title":["Detection and exclusion of interatrial shunts by two-dimensional echocardiography and peripheral venous injection."],"prefix":"10.1161","volume":"59","author":[{"suffix":"Jr","given":"T D","family":"Fraker","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P J","family":"Harris","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V S","family":"Behar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J A","family":"Kisslo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","container-title":["Circulation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ahajournals.org\/doi\/pdf\/10.1161\/01.CIR.59.2.379","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,12]],"date-time":"2024-05-12T15:12:11Z","timestamp":1715526731000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ahajournals.org\/doi\/10.1161\/01.CIR.59.2.379"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1979,2]]},"references-count":0,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1979,2]]}},"alternative-id":["10.1161\/01.CIR.59.2.379"],"URL":"https:\/\/doi.org\/10.1161\/01.cir.59.2.379","relation":{},"ISSN":["0009-7322","1524-4539"],"issn-type":[{"value":"0009-7322","type":"print"},{"value":"1524-4539","type":"electronic"}],"subject":[],"published":{"date-parts":[[1979,2]]},"assertion":[{"value":"1979-02-01","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}