{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,25]],"date-time":"2026-02-25T19:02:58Z","timestamp":1772046178854,"version":"3.50.1"},"reference-count":0,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Circulation"],"published-print":{"date-parts":[[1988,3]]},"abstract":"<jats:p>The aim of this study in vitro of human fresh specimens was to quantitatively evaluate the contribution of the aqueous phase-intima interface (the first 400 msec of the reflected signal) in normal and atherosclerotic arterial walls. Seventy-five samples were studied, 15 normal, 15 fatty, 15 fibrofatty, 15 fibrous, and 15 calcific. A broadband transducer (4 to 14 MHz) was used. The aqueous phase-intima reflection (expressed in dB, mean +\/- SD) was lowest in the fatty plaques (-35.3 +\/- 2.5), differing in a highly significant way from that in all other groups: normal (-13.2 +\/- 8.8), fibrofatty (-20.4 +\/- 8.3), fibrous (-13.0 +\/- 9.7), calcific (-5.9 +\/- 3.4). The echo coming from the intima-media transition was of relatively low amplitude in normal and in fatty samples; typically, strong reflections from the intima-media transitions were present in the other pathologic subsets. In conclusion, the time domain echo pattern of the arterial wall may provide a useful clue to the structure of the plaque.<\/jats:p>","DOI":"10.1161\/01.cir.77.3.654","type":"journal-article","created":{"date-parts":[[2011,6,17]],"date-time":"2011-06-17T20:29:13Z","timestamp":1308342553000},"page":"654-659","update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":42,"title":["Time domain echo pattern evaluations from normal and atherosclerotic arterial walls: a study in vitro."],"prefix":"10.1161","volume":"77","author":[{"given":"E","family":"Picano","sequence":"first","affiliation":[{"name":"Istituto di Fisiologia clinica del CNR, Pisa, Italy."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L","family":"Landini","sequence":"additional","affiliation":[{"name":"Istituto di Fisiologia clinica del CNR, Pisa, Italy."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F","family":"Lattanzi","sequence":"additional","affiliation":[{"name":"Istituto di Fisiologia clinica del CNR, Pisa, Italy."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Salvadori","sequence":"additional","affiliation":[{"name":"Istituto di Fisiologia clinica del CNR, Pisa, Italy."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A","family":"Benassi","sequence":"additional","affiliation":[{"name":"Istituto di Fisiologia clinica del CNR, Pisa, Italy."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A","family":"L'Abbate","sequence":"additional","affiliation":[{"name":"Istituto di Fisiologia clinica del CNR, Pisa, Italy."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","container-title":["Circulation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ahajournals.org\/doi\/pdf\/10.1161\/01.CIR.77.3.654","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,12]],"date-time":"2024-05-12T15:05:15Z","timestamp":1715526315000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ahajournals.org\/doi\/10.1161\/01.CIR.77.3.654"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1988,3]]},"references-count":0,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1988,3]]}},"alternative-id":["10.1161\/01.CIR.77.3.654"],"URL":"https:\/\/doi.org\/10.1161\/01.cir.77.3.654","relation":{},"ISSN":["0009-7322","1524-4539"],"issn-type":[{"value":"0009-7322","type":"print"},{"value":"1524-4539","type":"electronic"}],"subject":[],"published":{"date-parts":[[1988,3]]},"assertion":[{"value":"1988-03-01","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}