{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,28]],"date-time":"2026-01-28T22:35:33Z","timestamp":1769639733708,"version":"3.49.0"},"reference-count":0,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"5","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Circulation"],"published-print":{"date-parts":[[1988,5]]},"abstract":"<jats:p>Clinical status, exercise treadmill performance, and hemodynamics were determined in 24 patients with symptomatic mitral stenosis before catheter balloon valvuloplasty (CBV) and at 3 months follow-up. Hemodynamic determinations at rest showed that mitral CBV performed by the double-balloon technique resulted in significant immediate decreases in mean pulmonary arterial wedge pressure (28 +\/- 7 to 16 +\/- 5 mm Hg, p less than .01), mean pulmonary arterial pressure (41 +\/- 11 to 33 +\/- 10 mm Hg, p less than .05), and mitral valve gradient (16 +\/- 7 to 6 +\/- 3 mm Hg, p less than .01), and significant increases in cardiac output (4.3 +\/- 1.1 to 5.0 +\/- 1.4 liters\/min, p less than .01). Mitral valve area increased from 1.0 +\/- 0.3 to 2.2 +\/- 0.7 cm2 (p less than .01). The mitral valve area was unchanged (2.0 +\/- 0.7 cm2, p = NS) at 3 months. The lower pulmonary arterial wedge pressure, pulmonary arterial pressure, and mitral valve gradient persisted at 3 month follow-up catheterization. Clinical examinations showed that before CBV, 21 of 24 patients were in New York Heart Association functional class III or IV; 3 months after CBV, 22 patients were in class I or II. Before CBV, the mean exercise treadmill time was 5.9 +\/- 3.2 min and it had increased to 9.8 +\/- 2.9 min (p less than .01) by the 3 month follow-up.(ABSTRACT TRUNCATED AT 250 WORDS)<\/jats:p>","DOI":"10.1161\/01.cir.77.5.1013","type":"journal-article","created":{"date-parts":[[2011,6,17]],"date-time":"2011-06-17T20:29:13Z","timestamp":1308342553000},"page":"1013-1021","update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":69,"title":["Improvement in exercise capacity and exercise hemodynamics 3 months after double-balloon, catheter balloon valvuloplasty treatment of patients with symptomatic mitral stenosis."],"prefix":"10.1161","volume":"77","author":[{"given":"C R","family":"McKay","sequence":"first","affiliation":[{"name":"Department of Medicine, LAC-USC Medical Center 90033."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D T","family":"Kawanishi","sequence":"additional","affiliation":[{"name":"Department of Medicine, LAC-USC Medical Center 90033."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A","family":"Kotlewski","sequence":"additional","affiliation":[{"name":"Department of Medicine, LAC-USC Medical Center 90033."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K","family":"Parise","sequence":"additional","affiliation":[{"name":"Department of Medicine, LAC-USC Medical Center 90033."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T","family":"Odom-Maryon","sequence":"additional","affiliation":[{"name":"Department of Medicine, LAC-USC Medical Center 90033."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A","family":"Gonzalez","sequence":"additional","affiliation":[{"name":"Department of Medicine, LAC-USC Medical Center 90033."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C L","family":"Reid","sequence":"additional","affiliation":[{"name":"Department of Medicine, LAC-USC Medical Center 90033."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S H","family":"Rahimtoola","sequence":"additional","affiliation":[{"name":"Department of Medicine, LAC-USC Medical Center 90033."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","container-title":["Circulation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ahajournals.org\/doi\/pdf\/10.1161\/01.CIR.77.5.1013","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,12]],"date-time":"2024-05-12T14:57:14Z","timestamp":1715525834000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ahajournals.org\/doi\/10.1161\/01.CIR.77.5.1013"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1988,5]]},"references-count":0,"journal-issue":{"issue":"5","published-print":{"date-parts":[[1988,5]]}},"alternative-id":["10.1161\/01.CIR.77.5.1013"],"URL":"https:\/\/doi.org\/10.1161\/01.cir.77.5.1013","relation":{},"ISSN":["0009-7322","1524-4539"],"issn-type":[{"value":"0009-7322","type":"print"},{"value":"1524-4539","type":"electronic"}],"subject":[],"published":{"date-parts":[[1988,5]]},"assertion":[{"value":"1988-05-01","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}