{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,4]],"date-time":"2026-02-04T16:01:17Z","timestamp":1770220877461,"version":"3.49.0"},"reference-count":19,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"6","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Circulation"],"published-print":{"date-parts":[[1995,3,15]]},"abstract":"<jats:p>\n            <jats:italic>Background<\/jats:italic>\n            Transcatheter closure of cardiovascular defects remains a challenge. Several occlusion devices are available, but each device has limitations. The purpose of this study was to evaluate the new Gianturco-Grifka vascular occlusion device (GGVOD) in a canine model.\n          <\/jats:p>\n          <jats:p>\n            <jats:italic>Methods and Results<\/jats:italic>\n            A total of 26 GGVODs were implanted as part of short- and long-term studies. In the short-term study, 1 GGVOD was implanted in each of 11 systemic arteries from 3.2 to 9.0 mm in diameter. All 11 arteries were occluded immediately. In the long-term study, an aortopulmonary shunt was placed in 10 dogs (9, Gore-tex graft; 1, subclavian artery) followed by GGVOD implantation; additionally, a GGVOD was implanted in 5 subclavian arteries. The dogs were boarded for 3 to 6 months, then recatheterized and euthanatized. Immediately after implantation, the 5 subclavian arteries and 9 Gore-tex shunts were occluded completely; the 1 subclavian artery shunt had a small residual leak. At recatheterization, all 10 shunts and 5 subclavian arteries were occluded completely. Necropsy revealed all shunts to be occluded, with the aortic and pulmonic orifices covered with a neointimal layer. The mean fluoroscopic time needed for GGVOD implantation was 9 minutes (range, 3 to 22 minutes).\n          <\/jats:p>\n          <jats:p>\n            <jats:italic>Conclusions<\/jats:italic>\n            (1) In a canine model, the GGVOD is effective for transcatheter occlusion of arteries and aortopulmonary shunts from 3 to 9 mm in diameter. Possible indications in children include aortopulmonary collateral vessels, long patent ductus arteriosus, systemic-pulmonary shunts, AV malformations, and arteries supplying tumors. (2) GGVOD implantation requires a short fluoroscopic time.\n          <\/jats:p>","DOI":"10.1161\/01.cir.91.6.1840","type":"journal-article","created":{"date-parts":[[2012,6,12]],"date-time":"2012-06-12T00:34:42Z","timestamp":1339461282000},"page":"1840-1846","update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":51,"title":["New Gianturco-Grifka Vascular Occlusion Device"],"prefix":"10.1161","volume":"91","author":[{"given":"Ronald G.","family":"Grifka","sequence":"first","affiliation":[{"name":"From the Lillie Frank Abercrombie Section of Pediatric Cardiology, Texas Children\u2019s Hospital, Baylor College of Medicine, and Texas Heart Institute, Houston."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Charles E.","family":"Mullins","sequence":"additional","affiliation":[{"name":"From the Lillie Frank Abercrombie Section of Pediatric Cardiology, Texas Children\u2019s Hospital, Baylor College of Medicine, and Texas Heart Institute, Houston."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cesare","family":"Gianturco","sequence":"additional","affiliation":[{"name":"From the Lillie Frank Abercrombie Section of Pediatric Cardiology, Texas Children\u2019s Hospital, Baylor College of Medicine, and Texas Heart Institute, Houston."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael R.","family":"Nihill","sequence":"additional","affiliation":[{"name":"From the Lillie Frank Abercrombie Section of Pediatric Cardiology, Texas Children\u2019s Hospital, Baylor College of Medicine, and Texas Heart Institute, Houston."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martin P.","family":"O\u2019Laughlin","sequence":"additional","affiliation":[{"name":"From the Lillie Frank Abercrombie Section of Pediatric Cardiology, Texas Children\u2019s Hospital, Baylor College of Medicine, and Texas Heart Institute, Houston."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael C.","family":"Slack","sequence":"additional","affiliation":[{"name":"From the Lillie Frank Abercrombie Section of Pediatric Cardiology, Texas Children\u2019s Hospital, Baylor College of Medicine, and Texas Heart Institute, Houston."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fred J.","family":"Clubb","sequence":"additional","affiliation":[{"name":"From the Lillie Frank Abercrombie Section of Pediatric Cardiology, Texas Children\u2019s Hospital, Baylor College of Medicine, and Texas Heart Institute, Houston."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Timothy J.","family":"Myers","sequence":"additional","affiliation":[{"name":"From the Lillie Frank Abercrombie Section of Pediatric Cardiology, Texas Children\u2019s Hospital, Baylor College of Medicine, and Texas Heart Institute, Houston."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"e_1_3_2_1_2","first-page":"303","volume":"15","year":"1985","unstructured":"Rashkind WJ, Tait MA. Interventional cardiac catheterization in congenital heart disease. Cardiovasc Clin. 1985;15:303-323.","journal-title":"Cardiovasc Clin"},{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1161\/circ.67.4.6825227"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF02307335"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1161\/circ.51.2.1112014"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1148\/115.1.55"},{"key":"e_1_3_2_6_2","first-page":"113","volume":"25","year":"1974","unstructured":"Carey LS, Grace DM. The brisk bleed: control by arterial catheterization and Gelfoam plug. 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