{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T17:35:30Z","timestamp":1787506530518,"version":"build-2736575974"},"reference-count":35,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Circulation"],"published-print":{"date-parts":[[1997,2,4]]},"abstract":"<jats:p>\n                    <jats:italic>Background<\/jats:italic>\n                    Pulmonary regurgitation (PR) is an important determinant of outcome after repair of tetralogy of Fallot. Baseline PR was measured by magnetic resonance (MR) phase velocity mapping and from real-time right ventricular pressure-volume loops with a conductance catheter. Subsequently, the impact of two loading maneuvers (increased airway pressure, simulated branch pulmonary artery stenosis) on PR was assessed by the conductance catheter method.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:italic>Methods and Results<\/jats:italic>\n                    Thirteen patients, 3 to 35 years after tetralogy of Fallot repair or pulmonary valvotomy, had PR measured by MR phase velocity mapping while breathing spontaneously. During catheterization under general anesthesia, PR was estimated from right ventricular pressure-volume loops generated by conductance and microtip pressure catheters. The effect of increased airway pressure (continuous positive airway pressure, 20 cm H\n                    <jats:sub>2<\/jats:sub>\n                    O; n=12) and simulated branch pulmonary artery stenosis (transient balloon occlusion of a branch pulmonary artery, n=7) was measured. Basal PR fraction derived by MR and from right ventricular pressure-volume loops had a correlation coefficient of .76 and mean of differences of 2.0\u00b118.2% (95% limits of agreement). Increased airway pressure increased PR (16.3\u00b111.4% to 25.7\u00b117.3%,\n                    <jats:italic>P<\/jats:italic>\n                    &lt;.01). Simulated branch pulmonary artery stenosis increased right ventricular end-systolic pressure (69.1\u00b121.4 to 78.7\u00b123.1 mm Hg,\n                    <jats:italic>P<\/jats:italic>\n                    &lt;.05) and PR (27.5\u00b111.3% to 36.9\u00b112.8%,\n                    <jats:italic>P<\/jats:italic>\n                    &lt;.05).\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:italic>Conclusions<\/jats:italic>\n                    There was reasonable agreement between MR phase velocity\u2013derived PR fraction and that obtained from right ventricular pressure-volume loops generated by use of conductance and pressure-microtip catheters. Exacerbation of PR by increased airway pressure and branch pulmonary stenosis may be relevant to the acute postoperative and long-term management, respectively, of patients after repair of tetralogy of Fallot.\n                  <\/jats:p>","DOI":"10.1161\/01.cir.95.3.643","type":"journal-article","created":{"date-parts":[[2012,6,11]],"date-time":"2012-06-11T20:41:02Z","timestamp":1339447262000},"page":"643-649","update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":92,"title":["Increased Airway Pressure and Simulated Branch Pulmonary Artery Stenosis Increase Pulmonary Regurgitation After Repair of Tetralogy of Fallot"],"prefix":"10.1161","volume":"95","author":[{"given":"Rajiv R.","family":"Chaturvedi","sequence":"first","affiliation":[{"name":"Royal Brompton Hospital and National Heart and Lung Institute, Imperial College, London, UK."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philip J.","family":"Kilner","sequence":"additional","affiliation":[{"name":"Royal Brompton Hospital and National Heart and Lung Institute, Imperial College, London, UK."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul A.","family":"White","sequence":"additional","affiliation":[{"name":"Royal Brompton Hospital and National Heart and Lung Institute, Imperial College, London, UK."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew","family":"Bishop","sequence":"additional","affiliation":[{"name":"Royal Brompton Hospital and National Heart and Lung Institute, Imperial College, London, UK."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard","family":"Szwarc","sequence":"additional","affiliation":[{"name":"Royal Brompton Hospital and National Heart and Lung Institute, Imperial College, London, UK."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew N.","family":"Redington","sequence":"additional","affiliation":[{"name":"Royal Brompton Hospital and National Heart and Lung Institute, Imperial College, London, UK."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"e_1_3_2_1_2","doi-asserted-by":"publisher","DOI":"10.1097\/00008480-199310000-00017"},{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5223(19)37745-1"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(10)80116-0"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.67.6.470"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(92)90506-T"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1161\/circ.92.2.231"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.60.1.57"},{"key":"e_1_3_2_8_2","doi-asserted-by":"crossref","unstructured":"Rebergen SA Chin JGJ Ottenkamp J van der Wall EE de Roos A. Pulmonary regurgitation in the late postoperative follow-up of tetralogy of Fallot: volumetric quantitation by nuclear magnetic resonance velocity mapping. Circulation. 1993;88(pt 1):2257-2266.","DOI":"10.1161\/01.CIR.88.5.2257"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8159.1992.tb04172.x"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.70.5.812"},{"key":"e_1_3_2_11_2","doi-asserted-by":"crossref","unstructured":"Altman DG. Practical Statistics for Medical Research. London UK: Chapman & Hall; 1991:398-403.","DOI":"10.1201\/9780429258589"},{"key":"e_1_3_2_12_2","unstructured":"Kirklin JW Barratt-Boyes BG. Cardiac Surgery. 2nd ed. New York NY: Churchill Livingstone; 1993:919-920."},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199308263290901"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-2007-1023399"},{"key":"e_1_3_2_15_2","first-page":"H619","volume":"254","year":"1988","unstructured":"Kass DA. Measuring right ventricular volumes. Am J Physiol. 1988;254:H619-H621.","journal-title":"Am J Physiol"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/0003-4975(89)90671-1"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(88)90771-0"},{"key":"e_1_3_2_18_2","first-page":"H622","volume":"254","year":"1988","unstructured":"Schwiep F, Cassidy SS, Ramanathan M, Johnson RL. Rapid in vivo determination of instantaneous right ventricular pressure and volume in dogs. Am J Physiol. 1988;254:H622-H630.","journal-title":"Am J Physiol"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.1161\/circ.81.2.2404635"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.eurheartj.a060751"},{"key":"e_1_3_2_21_2","unstructured":"Bishop A White P Oldershaw P Chaturvedi R Redington A. The use of conductance catheters to assess human right ventricular volumes: in vitro and in vivo validation. Eur Heart J. 1995;16(abstract supplement):310-P1754."},{"key":"e_1_3_2_22_2","first-page":"H869","volume":"38","year":"1995","unstructured":"Stamato TM, Szwarc RS, Benson LN. Measurement of right ventricular volume by conductance catheter in closed-chest pigs. Am J Physiol. 1995;38:H869-H876.","journal-title":"Am J Physiol"},{"key":"e_1_3_2_23_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0008-6363(96)88618-4"},{"key":"e_1_3_2_24_2","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.1984.57.5.1520"},{"key":"e_1_3_2_25_2","doi-asserted-by":"publisher","DOI":"10.1161\/circ.69.4.6697458"},{"key":"e_1_3_2_26_2","doi-asserted-by":"publisher","DOI":"10.1161\/circ.91.6.1782"},{"key":"e_1_3_2_27_2","unstructured":"Shekerdemian LS Shore DF Lincoln C Bush A Redington AN. Negative pressure ventilation improves cardiac output after right heart surgery. Circulation. 1996;94(suppl II):II-49-II-55."},{"key":"e_1_3_2_28_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5223(19)36472-4"},{"key":"e_1_3_2_29_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8159.1987.tb06043.x"},{"key":"e_1_3_2_30_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5223(19)38661-1"},{"key":"e_1_3_2_31_2","unstructured":"Warner KG Anderson JE Fulton DR Payne DD Geggel RL Marx GR. Restoration of the pulmonary valve reduces right ventricular volume overload after previous repair of tetralogy of Fallot. Circulation. 1993;88(pt 2):189-197."},{"key":"e_1_3_2_32_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5223(19)36968-5"},{"key":"e_1_3_2_33_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5223(19)36802-3"},{"key":"e_1_3_2_34_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5223(12)70161-7"},{"key":"e_1_3_2_35_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5223(95)70395-0"}],"container-title":["Circulation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ahajournals.org\/doi\/full\/10.1161\/01.CIR.95.3.643","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,12]],"date-time":"2024-05-12T12:28:47Z","timestamp":1715516927000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ahajournals.org\/doi\/10.1161\/01.CIR.95.3.643"}},"subtitle":["Real-Time Analysis With a Conductance Catheter Technique"],"short-title":[],"issued":{"date-parts":[[1997,2,4]]},"references-count":35,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1997,2,4]]}},"alternative-id":["10.1161\/01.CIR.95.3.643"],"URL":"https:\/\/doi.org\/10.1161\/01.cir.95.3.643","relation":{},"ISSN":["0009-7322","1524-4539"],"issn-type":[{"value":"0009-7322","type":"print"},{"value":"1524-4539","type":"electronic"}],"subject":[],"published":{"date-parts":[[1997,2,4]]},"assertion":[{"value":"1996-07-08","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"1996-09-30","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"1997-02-04","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}