{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,5,13]],"date-time":"2024-05-13T10:47:47Z","timestamp":1715597267549},"reference-count":0,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"6","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Hypertension"],"published-print":{"date-parts":[[1994,12]]},"abstract":"<jats:p>We determined the factors related to left ventricular mass adjusted for body size in 60 black (mean age, 13 +\/- 2 years) and 40 white (mean age, 14 +\/- 2 years) normotensive youths. The factors examined included age, sex, systolic blood pressure, diastolic blood pressure, plasma renin activity, plasma aldosterone concentration, and sodium and potassium intake as determined by 24-hour excretion. Sex (beta = 13.3, P &lt; .003), age (beta = 2.88, P &lt; .001), and systolic blood pressure (beta = 0.41, P &lt; .02) were independent predictors in the sample as a whole, accounting for 37% of the variance of left ventricular mass adjusted for height. Separate analyses were performed for black and white subjects. In the black subjects, age (beta = 4.4, P &lt; .004) followed by sex (beta = 11.85, P &lt; .02) were independent factors, accounting for 43% of the variance of left ventricular mass adjusted for height. In contrast, in white subjects systolic blood pressure (beta = 0.4, P &lt; .003) followed by sodium excretion (beta = 0.13, P &lt; .05) were independent factors, with gender (beta = 8.89, P &lt; .07) tending to account for 36% of the variance. Similar results were observed for left ventricular mass adjusted for body surface area. In conclusion, the age-related increase in adjusted left ventricular mass in black but not white youths may in part account for the early development of cardiovascular disease among the black population.<\/jats:p>","DOI":"10.1161\/01.hyp.24.6.747","type":"journal-article","created":{"date-parts":[[2012,6,12]],"date-time":"2012-06-12T00:24:03Z","timestamp":1339460643000},"page":"747-751","update-policy":"http:\/\/dx.doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":20,"title":["Racial differences in the age-related increase in left ventricular mass in youths."],"prefix":"10.1161","volume":"24","author":[{"given":"G A","family":"Harshfield","sequence":"first","affiliation":[{"name":"Department of Pediatrics, University of Tennessee, Memphis 38163."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D W","family":"Koelsch","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, University of Tennessee, Memphis 38163."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D A","family":"Pulliam","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, University of Tennessee, Memphis 38163."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B S","family":"Alpert","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, University of Tennessee, Memphis 38163."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P A","family":"Richey","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, University of Tennessee, Memphis 38163."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J A","family":"Becker","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, University of Tennessee, Memphis 38163."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","container-title":["Hypertension"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ahajournals.org\/doi\/pdf\/10.1161\/01.HYP.24.6.747","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,12]],"date-time":"2024-05-12T17:29:22Z","timestamp":1715534962000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ahajournals.org\/doi\/10.1161\/01.HYP.24.6.747"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1994,12]]},"references-count":0,"journal-issue":{"issue":"6","published-print":{"date-parts":[[1994,12]]}},"alternative-id":["10.1161\/01.HYP.24.6.747"],"URL":"https:\/\/doi.org\/10.1161\/01.hyp.24.6.747","relation":{},"ISSN":["0194-911X","1524-4563"],"issn-type":[{"value":"0194-911X","type":"print"},{"value":"1524-4563","type":"electronic"}],"subject":[],"published":{"date-parts":[[1994,12]]},"assertion":[{"value":"1994-12-01","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}