{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T12:24:44Z","timestamp":1791894284040,"version":"4.3.4"},"reference-count":14,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Hypertension"],"published-print":{"date-parts":[[1996,1]]},"abstract":"<jats:p>\n                    <jats:italic>Abstract<\/jats:italic>\n                    The prevalence and clinical picture of hypertensive urgencies and emergencies in an emergency department are poorly known. The aim of the present study was to evaluate the prevalence of hypertensive crises (urgencies and emergencies) in an emergency department during 12 months of observation and the frequency of end-organ damage with related clinical pictures during the first 24 hours after presentation. Hypertensive crises (76% urgencies, 24% emergencies) represented more than one fourth of all medical urgencies-emergencies. The most frequent signs of presentation were headache (22%), epistaxis (17%), faintness, and psychomotor agitation (10%) in hypertensive urgencies and chest pain (27%), dyspnea (22%), and neurological deficit (21%) in hypertensive emergencies. Types of end-organ damage associated with hypertensive emergencies included cerebral infarction (24%), acute pulmonary edema (23%), and hypertensive encephalopathy (16%) as well as cerebral hemorrhage, which accounted for only 4.5%. Age (67\u00b116 versus 60\u00b114 years [mean\u00b1SD],\n                    <jats:italic>P<\/jats:italic>\n                    &lt;.001) and diastolic blood pressure (130\u00b115 versus 126\u00b110 mm Hg,\n                    <jats:italic>P<\/jats:italic>\n                    &lt;.002) were higher in hypertensive emergencies than urgencies. Hypertension that was unknown at presentation was present in 8% of hypertensive emergencies and 28% of hypertensive urgencies. In conclusion hypertensive urgencies and emergencies are common events in the emergency department and differ in their clinical patterns of presentation. Cerebral infarction and acute pulmonary edema are the most frequent types of end-organ damage in hypertensive emergencies.\n                  <\/jats:p>","DOI":"10.1161\/01.hyp.27.1.144","type":"journal-article","created":{"date-parts":[[2012,6,11]],"date-time":"2012-06-11T20:53:46Z","timestamp":1339448026000},"page":"144-147","update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":360,"title":["Hypertensive Urgencies and Emergencies"],"prefix":"10.1161","volume":"27","author":[{"given":"Bruno","family":"Zampaglione","sequence":"first","affiliation":[{"name":"From the Ward of Internal Medicine II and Emergency Department, Martini Hospital, Turin, and Institute of Internal Medicine, University of Turin (Italy)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudio","family":"Pascale","sequence":"additional","affiliation":[{"name":"From the Ward of Internal Medicine II and Emergency Department, Martini Hospital, Turin, and Institute of Internal Medicine, University of Turin (Italy)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco","family":"Marchisio","sequence":"additional","affiliation":[{"name":"From the Ward of Internal Medicine II and Emergency Department, Martini Hospital, Turin, and Institute of Internal Medicine, University of Turin (Italy)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paolo","family":"Cavallo-Perin","sequence":"additional","affiliation":[{"name":"From the Ward of Internal Medicine II and Emergency Department, Martini Hospital, Turin, and Institute of Internal Medicine, University of Turin (Italy)."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"e_1_3_2_1_2","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.1993.00410020010002"},{"key":"e_1_3_2_2_2","doi-asserted-by":"crossref","unstructured":"Ault M Ellrodt A. Pathophysiological events leading to end-organ effects of acute hypertension. Am J Emerg Med. 1985;3(suppl):10-15.","DOI":"10.1016\/0735-6757(85)90227-X"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.3949\/ccjm.51.2.421"},{"key":"e_1_3_2_4_2","unstructured":"Kaplan NM. Clinical Hypertension. Baltimore Md: Williams & Wilkins; 1991;329-348."},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199010253231706"},{"key":"e_1_3_2_6_2","unstructured":"Dellinger RP. Hypertensive emergencies and urgencies. In: Civetta JM Taylor RW Kirby RR eds. Critical Care. Philadelphia Pa: JB Lippincott Co: 1992;1209-1217."},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1177\/000331979104201106"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-8703(86)90582-X"},{"key":"e_1_3_2_9_2","first-page":"9","volume":"51","year":"1992","unstructured":"Pascale C, Zampaglione B, Marchisio M. Management of hyper-tensive crisis: nifedipine in comparison with captopril, clonidine, and furosemide. Curr Ther Res. 1992;51:9-18.","journal-title":"Curr Ther Res"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/0736-4679(87)90208-3"},{"key":"e_1_3_2_11_2","unstructured":"Hudson LD. Essentials of critical care medicine: approach to the critically ill patient. In: Kelley WN ed. Textbook of Internal Medicine. Philadelphia Pa: JB Lippincott Co; 1992;1842-1844."},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(87)91027-7"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0025-7125(16)31313-X"},{"key":"e_1_3_2_14_2","first-page":"42","volume":"1","year":"1980","unstructured":"Kincaid-Smith P. Malignant hypertension. Cardiovasc Rev Rep. 1980;1:42-50.","journal-title":"Cardiovasc Rev Rep"}],"container-title":["Hypertension"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ahajournals.org\/doi\/full\/10.1161\/01.HYP.27.1.144","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,12]],"date-time":"2024-05-12T13:30:08Z","timestamp":1715520608000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ahajournals.org\/doi\/10.1161\/01.HYP.27.1.144"}},"subtitle":["Prevalence and Clinical Presentation"],"short-title":[],"issued":{"date-parts":[[1996,1]]},"references-count":14,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1996,1]]}},"alternative-id":["10.1161\/01.HYP.27.1.144"],"URL":"https:\/\/doi.org\/10.1161\/01.hyp.27.1.144","relation":{},"ISSN":["0194-911X","1524-4563"],"issn-type":[{"value":"0194-911X","type":"print"},{"value":"1524-4563","type":"electronic"}],"subject":[],"published":{"date-parts":[[1996,1]]},"assertion":[{"value":"1995-04-27","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"1995-09-11","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"1996-01-01","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}