{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,3]],"date-time":"2026-04-03T18:14:09Z","timestamp":1775240049058,"version":"3.50.1"},"reference-count":46,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Hypertension"],"published-print":{"date-parts":[[1998,1]]},"abstract":"<jats:p>\n            Gestational hypertension and malnutrition are associated with hypertension and ischemic heart disease in the adult human. The impact of the gestational environment on the adult blood pressure in two well-characterized genetically homogeneous rat strains, the hypertensive SS\/jr and normotensive SR\/jr, was studied by cross-fostering within 6 hours of birth and by embryo transplantation with the recipient dam nursing the transplanted pups. Systolic blood pressure (BP) was measured by tail-cuff plethysmography twice a week after the age of 7 weeks. The lactational environment (cross-fostering) had no effect on blood pressure. Embryo transfer between like strains had no effect on the development of hypertension, nor did the BP of R transferred to S (RetS) differ from that of normal R or RetR. At 7 weeks of age, the BP of SetR was significantly lower than that of S or SetS (\n            <jats:italic>P<\/jats:italic>\n            &lt;.01) and was similar to that of RetR and R. With age, the blood pressures of the S, SetS and SetR increased at approximately the same rate but from a significantly different baseline. Salt-sensitivity in the S and resistance in the R were not altered. The protective effect of the R gestational environment on SetR female BP was abrogated during whelping and lactation. Embryo transfer and cross-fostering did not alter the weight of rats older than 7 weeks. Because the BP of the R dams were significantly lower than that of the S dams, these studies do not distinguish between the effects of the R dams\u2019 lower blood pressure per se and hormonal influences of the R uterus on the S blood pressure phenotype.\n          <\/jats:p>","DOI":"10.1161\/01.hyp.31.1.540","type":"journal-article","created":{"date-parts":[[2012,6,12]],"date-time":"2012-06-12T00:53:46Z","timestamp":1339462426000},"page":"540-545","update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":7,"title":["Modulation of Blood Pressure in the Dahl SS\/jr Rat by Embryo Transfer"],"prefix":"10.1161","volume":"31","author":[{"given":"H. Michael","family":"Kubisch","sequence":"first","affiliation":[{"name":"From Department of Animal Sciences and Division of Endocrinology (H.M.K.), Department of Internal Medicine, University of Missouri-Columbia and Research Service, Harry S Truman Memorial Veterans Hospital Columbia, Missouri"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sumathy","family":"Mathialagan","sequence":"additional","affiliation":[{"name":"From Department of Animal Sciences and Division of Endocrinology (H.M.K.), Department of Internal Medicine, University of Missouri-Columbia and Research Service, Harry S Truman Memorial Veterans Hospital Columbia, Missouri"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elise P.","family":"Go\u0301mez-Sa\u0301nchez","sequence":"additional","affiliation":[{"name":"From Department of Animal Sciences and Division of Endocrinology (H.M.K.), Department of Internal Medicine, University of Missouri-Columbia and Research Service, Harry S Truman Memorial Veterans Hospital Columbia, Missouri"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"e_1_3_2_1_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.301.6746.259"},{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1136\/adc.66.11.1291"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/0140-6736(93)90148-A"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/0140-6736(93)90138-7"},{"key":"e_1_3_2_5_2","first-page":"259","volume":"87","year":"1994","unstructured":"Seckl JR. 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