{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T09:49:26Z","timestamp":1789724966865,"version":"4.0.1"},"reference-count":25,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"5","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Hypertension"],"published-print":{"date-parts":[[2000,11]]},"abstract":"<jats:p>\n            <jats:italic>Abstract<\/jats:italic>\n            \u2014Psychosocial factors,  including type A personality, anger, hostility, and anxiety, have been  implicated in the pathogenesis of cardiovascular  disease. Abnormal sympathetic responses to stress may help explain the  link between certain behavior patterns and  cardiovascular disease. We tested the hypothesis that  in normal humans, type A personality characteristics are associated  with exaggerated heart rate, pressor, and sympathetic nerve responses  to mental and physical stress. We measured heart rate, blood pressure,  and muscle sympathetic nerve activity (obtained with direct intraneural  recordings) at rest and during stress in 45 healthy subjects  (19 men and 26 women, age 29.2\u00b18.7 years) who had no chronic diseases  and were taking no medications. Subjects were divided into tertiles  based on type A scores. There were no significant differences in  sympathetic or hemodynamic reactivity among the 3  different intensity levels of type A characteristics. Baseline measures  and responses to stress tests were similar across the 3 groups.  Sympathetic and hemodynamic changes during stress tests  were also similar in subject groups stratified according to anger scale  and cynicism scale. Sympathetic nerve and hemodynamic  measurements at rest and during stress were not different in normal  subjects with type A characteristics. Abnormalities in sympathetic or  cardiovascular reactivity are unlikely to be implicated  in any excess of cardiovascular disease in people with  type A personality characteristics.\n          <\/jats:p>","DOI":"10.1161\/01.hyp.36.5.830","type":"journal-article","created":{"date-parts":[[2012,6,12]],"date-time":"2012-06-12T00:25:31Z","timestamp":1339460731000},"page":"830-833","update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":11,"title":["Personality Type and Neural Circulatory Control"],"prefix":"10.1161","volume":"36","author":[{"given":"Kathleen E.","family":"Schroeder","sequence":"first","affiliation":[{"name":"From the Department of Internal Medicine (K.S., D.D., V.K.S.), Mayo  Clinic, Rochester, Minn; Medical University of Gdansk, Gdansk, Poland (K.N.);  Tottori University, Tottori, Japan (M.K.); and Department of Internal Medicine  (C.P.) and the Division of Clinical and Administrative Pharmacy (B.P.),  University of Iowa (Iowa City)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Krzysztof","family":"Narkiewicz","sequence":"additional","affiliation":[{"name":"From the Department of Internal Medicine (K.S., D.D., V.K.S.), Mayo  Clinic, Rochester, Minn; Medical University of Gdansk, Gdansk, Poland (K.N.);  Tottori University, Tottori, Japan (M.K.); and Department of Internal Medicine  (C.P.) and the Division of Clinical and Administrative Pharmacy (B.P.),  University of Iowa (Iowa City)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masahiko","family":"Kato","sequence":"additional","affiliation":[{"name":"From the Department of Internal Medicine (K.S., D.D., V.K.S.), Mayo  Clinic, Rochester, Minn; Medical University of Gdansk, Gdansk, Poland (K.N.);  Tottori University, Tottori, Japan (M.K.); and Department of Internal Medicine  (C.P.) and the Division of Clinical and Administrative Pharmacy (B.P.),  University of Iowa (Iowa City)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine","family":"Pesek","sequence":"additional","affiliation":[{"name":"From the Department of Internal Medicine (K.S., D.D., V.K.S.), Mayo  Clinic, Rochester, Minn; Medical University of Gdansk, Gdansk, Poland (K.N.);  Tottori University, Tottori, Japan (M.K.); and Department of Internal Medicine  (C.P.) and the Division of Clinical and Administrative Pharmacy (B.P.),  University of Iowa (Iowa City)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bradley","family":"Phillips","sequence":"additional","affiliation":[{"name":"From the Department of Internal Medicine (K.S., D.D., V.K.S.), Mayo  Clinic, Rochester, Minn; Medical University of Gdansk, Gdansk, Poland (K.N.);  Tottori University, Tottori, Japan (M.K.); and Department of Internal Medicine  (C.P.) and the Division of Clinical and Administrative Pharmacy (B.P.),  University of Iowa (Iowa City)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diane","family":"Davison","sequence":"additional","affiliation":[{"name":"From the Department of Internal Medicine (K.S., D.D., V.K.S.), Mayo  Clinic, Rochester, Minn; Medical University of Gdansk, Gdansk, Poland (K.N.);  Tottori University, Tottori, Japan (M.K.); and Department of Internal Medicine  (C.P.) and the Division of Clinical and Administrative Pharmacy (B.P.),  University of Iowa (Iowa City)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Virend K.","family":"Somers","sequence":"additional","affiliation":[{"name":"From the Department of Internal Medicine (K.S., D.D., V.K.S.), Mayo  Clinic, Rochester, Minn; Medical University of Gdansk, Gdansk, Poland (K.N.);  Tottori University, Tottori, Japan (M.K.); and Department of Internal Medicine  (C.P.) and the Division of Clinical and Administrative Pharmacy (B.P.),  University of Iowa (Iowa City)."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"e_1_3_2_1_2","doi-asserted-by":"publisher","DOI":"10.1136\/jech.42.3.226"},{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.hyp.18.1.72"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1097\/00004872-199917010-00017"},{"key":"e_1_3_2_4_2","unstructured":"Wilson G Nathan P O\u2019Leary K Clark L. 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