{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,18]],"date-time":"2026-01-18T07:17:12Z","timestamp":1768720632041,"version":"3.49.0"},"reference-count":33,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"6","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Hypertension"],"published-print":{"date-parts":[[2000,12]]},"abstract":"<jats:p>\n            <jats:italic>Abstract<\/jats:italic>\n            \u2014Laboratory research on  hypertension often is performed with cold stress to elicit  vasoconstriction and increases in blood pressure. Several studies have  shown that cardiovascular responses to the cold pressor  test predict the development of hypertension. We extended this research  by comparing cardiovascular responses to a traditional  forehead cold pressor test and a naturalistic whole-body cold exposure.  We evaluated blood pressure and impedance cardiographic measures of  cardiac output and total peripheral resistance in healthy  black (n=69) and white (n=47) adolescents (mean age, 14.7 years) during  forehead cold pressor (3\u00b0C to 4\u00b0C) and passive whole-body exposure  to a cold chamber (8\u00b0C to 10\u00b0C). Both tasks elicited increases in  vascular resistance and blood pressure, but forehead cold elicited an  increase in cardiac output, whereas whole-body cold elicited a decrease  in cardiac output (\n            <jats:italic>P<\/jats:italic>\n            &lt;0.05). Consistent with  previous research, there was a tendency toward greater  vasoconstrictive reactivity to cold stress in blacks  than in whites, particularly during whole-body cold exposure  (\n            <jats:italic>P<\/jats:italic>\n            &lt;0.05). Cardiovascular reactivity  correlated significantly between tasks, but substantial intertask  consistency occurred only for cardiac and vascular  reactivity in male subjects (\n            <jats:italic>r<\/jats:italic>\n            &gt;0.30) but not in female  subjects (\n            <jats:italic>r<\/jats:italic>\n            &lt;0.15). These gender differences might  reflect diminished adrenergic receptor function in female subjects. We  conclude that whole-body cold exposure offers a viable, relatively  naturalistic alternative to traditional cold pressor tests for the  assessment of cardiovascular reactivity.\n          <\/jats:p>","DOI":"10.1161\/01.hyp.36.6.1013","type":"journal-article","created":{"date-parts":[[2012,6,12]],"date-time":"2012-06-12T00:25:31Z","timestamp":1339460731000},"page":"1013-1017","update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":15,"title":["Consistency of Hemodynamic Responses to Cold Stress in Adolescents"],"prefix":"10.1161","volume":"36","author":[{"given":"Robert M.","family":"Kelsey","sequence":"first","affiliation":[{"name":"From the University of Tennessee College of Medicine, Memphis."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephen M.","family":"Patterson","sequence":"additional","affiliation":[{"name":"From the University of Tennessee College of Medicine, Memphis."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marie","family":"Barnard","sequence":"additional","affiliation":[{"name":"From the University of Tennessee College of Medicine, Memphis."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bruce S.","family":"Alpert","sequence":"additional","affiliation":[{"name":"From the University of Tennessee College of Medicine, Memphis."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"e_1_3_2_1_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-8986.1987.tb00345.x"},{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0895-7061(99)00144-2"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1161\/circ.101.19.2284"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.1975.39.2.181"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-8986.1986.tb00602.x"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-8986.1993.tb03203.x"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-8986.1975.tb01289.x"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-8986.1991.tb01985.x"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-8986.1993.tb02058.x"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.hyp.14.5.524"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.hyp.6.3.301"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1161\/hyp.25.1.71"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0025-7125(05)70568-X"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0895-7061(99)00241-1"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1097\/00006842-198801000-00007"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.hyp.22.6.801"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1093\/ajh\/7.1.15"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1097\/00004872-199010000-00012"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/0895-7061(95)00036-O"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.1097\/00006842-199005000-00003"},{"key":"e_1_3_2_21_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.hyp.2.5.686"},{"key":"e_1_3_2_22_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-8986.1990.tb02171.x"},{"key":"e_1_3_2_23_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(82)80696-3"},{"key":"e_1_3_2_24_2","doi-asserted-by":"publisher","DOI":"10.1016\/0140-6736(92)90597-V"},{"key":"e_1_3_2_25_2","doi-asserted-by":"publisher","DOI":"10.1111\/1469-8986.3660818"},{"key":"e_1_3_2_26_2","unstructured":"Tabachnick BG Fidell LS. 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