{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,9,3]],"date-time":"2024-09-03T08:56:16Z","timestamp":1725353776285},"reference-count":0,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Circulation Research"],"published-print":{"date-parts":[[1971,4]]},"abstract":"<jats:p>\n            Atrial septal defect is associated with increased diameter and pulsation of the pulmonary arteries. The high pulmonary flow rate produces turbulence and a murmur. Intraluminal pressure is normal and vessel wall elastic properties may be altered as in poststenotic dilatation. Pulmonary artery angiograms in 6 normal patients, 9 with pulmonary stenosis and 10 with atrial septal defect were recorded on film, projected and traced. Arterial diameters at maximum systole and diastole were measured and, with intraluminal pressures, 2 points on the elastic diagram were calculated. These points lay on the initial linear portion of the graph so that a line through them to zero wall tension gave the resting radius (R\n            <jats:sub>o<\/jats:sub>\n            ) Each radius value (R) was normalized by dividing by the corresponding R\n            <jats:sub>0<\/jats:sub>\n            . By plotting wall tension versus strain (R\/R\n            <jats:sub>0<\/jats:sub>\n            ), a regression line was obtained for normals significantly different from that for poststenotic dilatation (\n            <jats:italic>P<\/jats:italic>\n            &lt;0.01) and atrial septal defect (\n            <jats:italic>P<\/jats:italic>\n            &lt;0.01). The slope of each line approximated vessel elastance at normal pressures: normals, 2.15 x 10\n            <jats:sup>4<\/jats:sup>\n            dyne\/cm; poststenotic dilatation, 1.00 x 10\n            <jats:sup>4<\/jats:sup>\n            dyne\/cm; and atrial septal defect, 0.89 x 10\n            <jats:sup>4<\/jats:sup>\n            dyne\/cm. Increased pulmonary artery distensibility extends more peripherally in atrial septal defect, thus producing \"hilar dance.\" A case of Marfan's syndrome showed similar changes.\n          <\/jats:p>","DOI":"10.1161\/01.res.28.4.415","type":"journal-article","created":{"date-parts":[[2012,6,12]],"date-time":"2012-06-12T00:16:17Z","timestamp":1339460177000},"page":"415-425","update-policy":"http:\/\/dx.doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":13,"title":["Etiology of Pulmonary Artery Dilatation and Hilar Dance in Atrial Septal Defect"],"prefix":"10.1161","volume":"28","author":[{"given":"DEREK R.","family":"BOUGHNER","sequence":"first","affiliation":[{"name":"Departments of Biophysics and Medicine, University of Western Ontario, London 72, Ontario, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"MARGOT R.","family":"ROACH","sequence":"additional","affiliation":[{"name":"Departments of Biophysics and Medicine, University of Western Ontario, London 72, Ontario, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","container-title":["Circulation Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ahajournals.org\/doi\/pdf\/10.1161\/01.RES.28.4.415","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,12]],"date-time":"2024-05-12T19:22:48Z","timestamp":1715541768000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ahajournals.org\/doi\/10.1161\/01.RES.28.4.415"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1971,4]]},"references-count":0,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1971,4]]}},"alternative-id":["10.1161\/01.RES.28.4.415"],"URL":"https:\/\/doi.org\/10.1161\/01.res.28.4.415","relation":{},"ISSN":["0009-7330","1524-4571"],"issn-type":[{"value":"0009-7330","type":"print"},{"value":"1524-4571","type":"electronic"}],"subject":[],"published":{"date-parts":[[1971,4]]},"assertion":[{"value":"1970-07-06","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"1971-01-26","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"1971-04-01","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}