{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T09:54:29Z","timestamp":1791280469012,"version":"4.1.0"},"reference-count":27,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"11","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Stroke"],"published-print":{"date-parts":[[2004,11]]},"abstract":"<jats:p>\n            <jats:bold>\n              <jats:italic>Background and Purpose\u2014<\/jats:italic>\n            <\/jats:bold>\n            The cerebellum has an influence on motor excitability. We investigated if the location of a cerebellar infarction was crucial for changes of motor cortex excitability and if the electrophysiological findings were correlated with motor performance.\n          <\/jats:p>\n          <jats:p>\n            <jats:bold>\n              <jats:italic>Methods\u2014<\/jats:italic>\n            <\/jats:bold>\n            Transcranial magnetic stimulation was applied to study intracortical inhibition (ICI), intracortical facilitation (ICF), motor thresholds, and corticospinal excitability. Dexterity as a measure of motor performance was tested with the Nine-Hole-Peg Test (9HPT). Ratios (affected\/unaffected) were also calculated.\n          <\/jats:p>\n          <jats:p>\n            <jats:bold>\n              <jats:italic>Results\u2014<\/jats:italic>\n            <\/jats:bold>\n            ICI and ICF ratios were negatively correlated with 9HPT ratios in all patients (n=9). Compared with an age-matched control group, patients with lesions in the territory of the superior cerebellar artery (SCA) (n=3) or a lesion rostral of the dentate nucleus (n=1) had abnormally enhanced ICI and a loss of ICF (3 patients). Dexterity was impaired in all 4 patients. Motor excitability and motor performance normalized over the subsequent weeks. Patients with an infarct either in the territory of the anterior inferior cerebellar artery (n=2) or in the territory of the posterior inferior cerebellar artery (n=3) displayed motor excitability and motor performance within the normal range.\n          <\/jats:p>\n          <jats:p>\n            <jats:bold>\n              <jats:italic>Conclusion\u2014<\/jats:italic>\n            <\/jats:bold>\n            The superior part of the cerebellum has a strong influence on motor cortex excitability. We suggest that the enhancement of motor inhibition and reduction of motor facilitation is mediated by an impairment of the deep cerebellar nuclei.\n          <\/jats:p>","DOI":"10.1161\/01.str.0000143152.45801.ca","type":"journal-article","created":{"date-parts":[[2004,9,17]],"date-time":"2004-09-17T00:34:20Z","timestamp":1095381260000},"page":"2484-2488","update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":62,"title":["Motor Cortex Excitability After Cerebellar Infarction"],"prefix":"10.1161","volume":"35","author":[{"given":"J.","family":"Liepert","sequence":"first","affiliation":[{"name":"From the Department of Neurology (J.L., O.T., T.B., C.W.), and the Department of Neuroradiology (T.K.), University Hospital Eppendorf, Hamburg, Germany; and the General Hospital Altona (F.P.), Hamburg, Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T.","family":"Kucinski","sequence":"additional","affiliation":[{"name":"From the Department of Neurology (J.L., O.T., T.B., C.W.), and the Department of Neuroradiology (T.K.), University Hospital Eppendorf, Hamburg, Germany; and the General Hospital Altona (F.P.), Hamburg, Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"O.","family":"Tu\u0308scher","sequence":"additional","affiliation":[{"name":"From the Department of Neurology (J.L., O.T., T.B., C.W.), and the Department of Neuroradiology (T.K.), University Hospital Eppendorf, Hamburg, Germany; and the General Hospital Altona (F.P.), Hamburg, Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.","family":"Pawlas","sequence":"additional","affiliation":[{"name":"From the Department of Neurology (J.L., O.T., T.B., C.W.), and the Department of Neuroradiology (T.K.), University Hospital Eppendorf, Hamburg, Germany; and the General Hospital Altona (F.P.), Hamburg, Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T.","family":"Ba\u0308umer","sequence":"additional","affiliation":[{"name":"From the Department of Neurology (J.L., O.T., T.B., C.W.), and the Department of Neuroradiology (T.K.), University Hospital Eppendorf, Hamburg, Germany; and the General Hospital Altona (F.P.), Hamburg, Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Weiller","sequence":"additional","affiliation":[{"name":"From the Department of Neurology (J.L., O.T., T.B., C.W.), and the Department of Neuroradiology (T.K.), University Hospital Eppendorf, Hamburg, Germany; and the General Hospital Altona (F.P.), Hamburg, Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"e_1_3_2_1_2","unstructured":"Luciani L. 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