{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,20]],"date-time":"2025-09-20T21:31:29Z","timestamp":1758403889897},"reference-count":0,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Stroke"],"published-print":{"date-parts":[[1980,1]]},"abstract":"<jats:p>Measurements of total and regional cerebral blood flow in paralyzed rats maintained on 70% N2O\/30% O2 obtained by a diffusible tracer technique, iodoantipyrine, and by a particle distribution method, microspheres, have been compared. Total CBF values were in good agreement, 0.86 +\/- 0.07 ml\/g\/min (PaCO2 37.3 +\/- 1.5, iodoantipyrine method) and 0.88 +\/- 0.02 (PaCO2 36.2 +\/- 0.8, microsphere method). Regional cerebral blood flows showed good agreement with the 2 methods, with highest flow in the colliculi, striatum and cerebral cortex and lowest flows in the hypothalamus, pons medulla and cerebellum. The iodoantipyrine method is technically easier to perform and had a higher precision.<\/jats:p>","DOI":"10.1161\/01.str.11.1.39","type":"journal-article","created":{"date-parts":[[2011,6,17]],"date-time":"2011-06-17T20:08:03Z","timestamp":1308341283000},"page":"39-44","update-policy":"http:\/\/dx.doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":23,"title":["Regional cerebral blood flow in the rat as determined by particle distribution and by diffusible tracer."],"prefix":"10.1161","volume":"11","author":[{"given":"R W","family":"Horton","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T A","family":"Pedley","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B S","family":"Meldrum","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","container-title":["Stroke"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ahajournals.org\/doi\/pdf\/10.1161\/01.STR.11.1.39","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,12]],"date-time":"2024-05-12T21:26:57Z","timestamp":1715549217000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ahajournals.org\/doi\/10.1161\/01.STR.11.1.39"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1980,1]]},"references-count":0,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1980,1]]}},"alternative-id":["10.1161\/01.STR.11.1.39"],"URL":"https:\/\/doi.org\/10.1161\/01.str.11.1.39","relation":{},"ISSN":["0039-2499","1524-4628"],"issn-type":[{"value":"0039-2499","type":"print"},{"value":"1524-4628","type":"electronic"}],"subject":[],"published":{"date-parts":[[1980,1]]},"assertion":[{"value":"1980-01-01","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}