{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T09:09:14Z","timestamp":1790413754467,"version":"4.1.0"},"reference-count":0,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"6","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Stroke"],"published-print":{"date-parts":[[1988,6]]},"abstract":"<jats:p>Blood flow velocity of the middle cerebral artery was monitored during cardiopulmonary bypass procedures by means of transcranial Doppler ultrasonography. Our investigation was carried out in a group of 16 patients with severe carotid stenosis or occlusion and in a control group of 42 patients with no or stenosis of less than 50% local diameter reduction. After onset of cardiopulmonary bypass, both groups showed a short unstable phase followed by increased blood flow velocity (10% increase ipsilateral to the obstruction, 27% increase in the control group). Just before rewarming, blood flow velocity was still comparable to (control group -3%) or higher than (ipsilateral to obstructions +14%) prebypass values. Analysis of three patients with postoperative diffuse encephalopathy did not reveal reduced blood flow during cardiopulmonary bypass as a relevant factor. Two of the three showed luxury perfusion. Reduced perfusion due to carotid obstruction was not observed during cardiopulmonary bypass and therefore cannot be considered a significant risk factor for the development of intraoperative stroke.<\/jats:p>","DOI":"10.1161\/01.str.19.6.674","type":"journal-article","created":{"date-parts":[[2011,6,17]],"date-time":"2011-06-17T20:10:52Z","timestamp":1308341452000},"page":"674-680","update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":36,"title":["Transcranial Doppler ultrasonography during cardiopulmonary bypass in patients with severe carotid stenosis or occlusion."],"prefix":"10.1161","volume":"19","author":[{"given":"G M","family":"von Reutern","sequence":"first","affiliation":[{"name":"Department of Neurology, University of Freiburg, Federal Republic of Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A","family":"Hetzel","sequence":"additional","affiliation":[{"name":"Department of Neurology, University of Freiburg, Federal Republic of Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D","family":"Birnbaum","sequence":"additional","affiliation":[{"name":"Department of Neurology, University of Freiburg, Federal Republic of Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V","family":"Schlosser","sequence":"additional","affiliation":[{"name":"Department of Neurology, University of Freiburg, Federal Republic of Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","container-title":["Stroke"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ahajournals.org\/doi\/pdf\/10.1161\/01.STR.19.6.674","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,12]],"date-time":"2024-05-12T21:40:02Z","timestamp":1715550002000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ahajournals.org\/doi\/10.1161\/01.STR.19.6.674"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1988,6]]},"references-count":0,"journal-issue":{"issue":"6","published-print":{"date-parts":[[1988,6]]}},"alternative-id":["10.1161\/01.STR.19.6.674"],"URL":"https:\/\/doi.org\/10.1161\/01.str.19.6.674","relation":{},"ISSN":["0039-2499","1524-4628"],"issn-type":[{"value":"0039-2499","type":"print"},{"value":"1524-4628","type":"electronic"}],"subject":[],"published":{"date-parts":[[1988,6]]},"assertion":[{"value":"1988-06-01","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}