{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T08:32:52Z","timestamp":1791016372909,"version":"4.1.0"},"reference-count":0,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Stroke"],"published-print":{"date-parts":[[1993,3]]},"abstract":"<jats:p>Because the frequency of hemorrhagic transformation of cerebral infarcts is still a matter of controversy, we performed a prospective magnetic resonance imaging study in a series of consecutive patients with cardioembolic stroke.<\/jats:p>\n          <jats:p>Among 200 consecutive patients with transient ischemic attack or ischemic stroke, 41 were identified with a computed tomographically proven supratentorial infarct due to cardiogenic embolism. Magnetic resonance imaging (T1-weighted) was performed 3 weeks after the stroke in 35 of these 41 patients. Eight patients received anticoagulants. Magnetic resonance images showed hemorrhagic transformation in 68.6% (24) of the 35 infarcts, always without clinical deterioration. In a stepwise forward logistic regression analysis only the volume of infarction edema on the initial computed tomogram was linked significantly with the risk of hemorrhagic transformation (p = 0.037). Hemorrhages were a regular finding on magnetic resonance images of infarcts exceeding a volume of 10 cm3 (94.4%, 17 of 18).<\/jats:p>\n          <jats:p>Hemorrhagic transformation is a regular finding in medium-sized and large cardioembolic infarcts. Thus, in therapeutic and preventive studies of acute stroke the severity, not the frequency, of hemorrhages into brain infarcts should be the matter of interest.<\/jats:p>","DOI":"10.1161\/01.str.24.3.465","type":"journal-article","created":{"date-parts":[[2011,6,17]],"date-time":"2011-06-17T20:08:03Z","timestamp":1308341283000},"page":"465-468","update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":82,"title":["Hemorrhagic transformation in cardioembolic cerebral infarction."],"prefix":"10.1161","volume":"24","author":[{"given":"C R","family":"Hornig","sequence":"first","affiliation":[{"name":"Department of Neurology, Justus Liebig University, Giessen, FRG."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T","family":"Bauer","sequence":"additional","affiliation":[{"name":"Department of Neurology, Justus Liebig University, Giessen, FRG."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C","family":"Simon","sequence":"additional","affiliation":[{"name":"Department of Neurology, Justus Liebig University, Giessen, FRG."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S","family":"Trittmacher","sequence":"additional","affiliation":[{"name":"Department of Neurology, Justus Liebig University, Giessen, FRG."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"W","family":"Dorndorf","sequence":"additional","affiliation":[{"name":"Department of Neurology, Justus Liebig University, Giessen, FRG."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","container-title":["Stroke"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ahajournals.org\/doi\/pdf\/10.1161\/01.STR.24.3.465","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,12]],"date-time":"2024-05-12T22:08:47Z","timestamp":1715551727000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ahajournals.org\/doi\/10.1161\/01.STR.24.3.465"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1993,3]]},"references-count":0,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1993,3]]}},"alternative-id":["10.1161\/01.STR.24.3.465"],"URL":"https:\/\/doi.org\/10.1161\/01.str.24.3.465","relation":{},"ISSN":["0039-2499","1524-4628"],"issn-type":[{"value":"0039-2499","type":"print"},{"value":"1524-4628","type":"electronic"}],"subject":[],"published":{"date-parts":[[1993,3]]},"assertion":[{"value":"1993-03-01","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}