{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,21]],"date-time":"2026-02-21T03:27:08Z","timestamp":1771644428913,"version":"3.50.1"},"reference-count":0,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"8","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Stroke"],"published-print":{"date-parts":[[1993,8]]},"abstract":"<jats:p>The relation between the redistribution phenomenon and regional cerebral blood flow and its clinical significance were investigated in stroke patients.<\/jats:p>\n          <jats:p>Single-photon emission computed tomography studies using N-isopropyl-p-[123I]iodoamphetamine were performed on 16 patients (26 to 77 years old) with chronic infarction and 10 age-matched normal control subjects. Regional cerebral blood flow was quantitatively measured by a microsphere model, and the redistribution on delayed images was analyzed in ischemic lesions.<\/jats:p>\n          <jats:p>Supratentorial mean cerebral blood flow and the ratio of gray matter to white matter in normal subjects were 52.7 +\/- 5.0 mL\/100 g per minute and 2.34, respectively. Low-activity areas of ischemic lesions on early images were classified into two abnormal zones, an infarct area and a peri-infarct area. These regions were characterized by regional blood flow averaging 9 to 20 mL\/100 g per minute and 22 to 41 mL\/100 g per minute, respectively. Redistribution, which was minimally present in the infarct area, was markedly enhanced in the peri-infarct area. After bypass surgery, we observed a significant increase of blood flow (+22%) in the peri-infarct area.<\/jats:p>\n          <jats:p>The data indicate that the redistribution phenomenon depends on the maintenance of a minimal blood flow that would sustain cellular function and that this phenomenon is useful to evaluate bypass surgery in patients with chronic infarction.<\/jats:p>","DOI":"10.1161\/01.str.24.8.1167","type":"journal-article","created":{"date-parts":[[2011,6,17]],"date-time":"2011-06-17T20:08:03Z","timestamp":1308341283000},"page":"1167-1172","update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":6,"title":["Regional cerebral blood flow measured with N-isopropyl-p-[123I]iodoamphetamine and its redistribution in ischemic cerebrovascular disease."],"prefix":"10.1161","volume":"24","author":[{"given":"I","family":"Odano","sequence":"first","affiliation":[{"name":"Department of Radiology, Niigata University School of Medicine, Japan."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T","family":"Tsuchiya","sequence":"additional","affiliation":[{"name":"Department of Radiology, Niigata University School of Medicine, Japan."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Nishihara","sequence":"additional","affiliation":[{"name":"Department of Radiology, Niigata University School of Medicine, Japan."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K","family":"Sakai","sequence":"additional","affiliation":[{"name":"Department of Radiology, Niigata University School of Medicine, Japan."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H","family":"Abe","sequence":"additional","affiliation":[{"name":"Department of Radiology, Niigata University School of Medicine, Japan."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R","family":"Tanaka","sequence":"additional","affiliation":[{"name":"Department of Radiology, Niigata University School of Medicine, Japan."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","container-title":["Stroke"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ahajournals.org\/doi\/pdf\/10.1161\/01.STR.24.8.1167","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,12]],"date-time":"2024-05-12T22:12:16Z","timestamp":1715551936000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ahajournals.org\/doi\/10.1161\/01.STR.24.8.1167"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1993,8]]},"references-count":0,"journal-issue":{"issue":"8","published-print":{"date-parts":[[1993,8]]}},"alternative-id":["10.1161\/01.STR.24.8.1167"],"URL":"https:\/\/doi.org\/10.1161\/01.str.24.8.1167","relation":{},"ISSN":["0039-2499","1524-4628"],"issn-type":[{"value":"0039-2499","type":"print"},{"value":"1524-4628","type":"electronic"}],"subject":[],"published":{"date-parts":[[1993,8]]},"assertion":[{"value":"1993-08-01","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}