{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T11:45:04Z","timestamp":1791114304460,"version":"4.1.0"},"reference-count":0,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"10","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Stroke"],"published-print":{"date-parts":[[1994,10]]},"abstract":"<jats:p>This study concerns the long-term prognosis of lacunar infarcts.<\/jats:p>\n          <jats:p>We report the analysis of our hospital-based series of 178 patients consecutively admitted for a lacunar syndrome due to a lacunar infarct diagnosed with computed tomography and magnetic resonance imaging. Demographic data, medical history, vascular risk factors, and imaging data were recorded for each patient. The follow-up was 35 +\/- 22 months.<\/jats:p>\n          <jats:p>The lacunar syndrome was pure motor hemiparesis in 69 patients (39%), ataxic hemiparesis in 45 patients (25.4%), pure sensory stroke in 15 patients (8.5%), sensorimotor stroke in 14 patients (7.9%), and miscellaneous syndrome in 34 patients (19.2%). The 4-year survival rate was 80 +\/- 4% and the 4-year survival rate without recurrent stroke was 85 +\/- 3.5%. Using Cox proportional-hazards analysis, the predictors of death were age (P &lt; .02), diabetes mellitus (P &lt; .05), and cigarette smoking (P &lt; .05). We did not find any predictors of recurrence. After 1 year, 74% of the patients had mild or no disability. Using logistic regression analysis, the predictive factors of disability were age more than 70 years (P &lt; .01), diabetes (P &lt; .01), history of stroke or transient ischemic attack (P &lt; .05), and type of lacunar syndrome (P &lt; .01). Imaging data, number of lacunes, and presence of leukoaraiosis were not predictors of outcome.<\/jats:p>\n          <jats:p>Our study suggests that with a high survival rate, a low recurrence rate, and a relatively good functional recovery, lacunar infarcts have a relatively favorable prognosis.<\/jats:p>","DOI":"10.1161\/01.str.25.10.2005","type":"journal-article","created":{"date-parts":[[2011,6,17]],"date-time":"2011-06-17T20:08:03Z","timestamp":1308341283000},"page":"2005-2009","update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":58,"title":["Long-term prognosis of symptomatic lacunar infarcts. A hospital-based study."],"prefix":"10.1161","volume":"25","author":[{"given":"I","family":"Clavier","sequence":"first","affiliation":[{"name":"Stroke Unit, Clinique Neurologique, Department of Clinical and Biological Neurosciences, Grenoble, France."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M","family":"Hommel","sequence":"additional","affiliation":[{"name":"Stroke Unit, Clinique Neurologique, Department of Clinical and Biological Neurosciences, Grenoble, France."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G","family":"Besson","sequence":"additional","affiliation":[{"name":"Stroke Unit, Clinique Neurologique, Department of Clinical and Biological Neurosciences, Grenoble, France."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B","family":"No\u00e8lle","sequence":"additional","affiliation":[{"name":"Stroke Unit, Clinique Neurologique, Department of Clinical and Biological Neurosciences, Grenoble, France."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J E","family":"Perret","sequence":"additional","affiliation":[{"name":"Stroke Unit, Clinique Neurologique, Department of Clinical and Biological Neurosciences, Grenoble, France."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","container-title":["Stroke"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ahajournals.org\/doi\/pdf\/10.1161\/01.STR.25.10.2005","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,12]],"date-time":"2024-05-12T22:05:17Z","timestamp":1715551517000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ahajournals.org\/doi\/10.1161\/01.STR.25.10.2005"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1994,10]]},"references-count":0,"journal-issue":{"issue":"10","published-print":{"date-parts":[[1994,10]]}},"alternative-id":["10.1161\/01.STR.25.10.2005"],"URL":"https:\/\/doi.org\/10.1161\/01.str.25.10.2005","relation":{},"ISSN":["0039-2499","1524-4628"],"issn-type":[{"value":"0039-2499","type":"print"},{"value":"1524-4628","type":"electronic"}],"subject":[],"published":{"date-parts":[[1994,10]]},"assertion":[{"value":"1994-10-01","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}