{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T19:59:03Z","timestamp":1779911943717,"version":"3.53.1"},"reference-count":0,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"11","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Stroke"],"published-print":{"date-parts":[[1994,11]]},"abstract":"<jats:p>Hyponatremia is a common complication after subarachnoid hemorrhage. In this study we investigated the relations among hyponatremia, plasma natriuretic peptides, and antidiuretic hormone concentrations after subarachnoid hemorrhage.<\/jats:p>\n          <jats:p>Blood samples for radioimmunoassay measurement of plasma brain natriuretic peptide-like immunoreactivity, atrial natriuretic peptide-like immunoreactivity, and antidiuretic hormone were obtained every 2 to 4 days until day 14 after subarachnoid hemorrhage.<\/jats:p>\n          <jats:p>Eleven of 20 patients with verified subarachnoid hemorrhage demonstrated mild hyponatremia (126 mEq\/L &lt; serum sodium &lt; 135 mEq\/L) during their clinical course. Atrial natriuretic peptide and antidiuretic hormone concentrations were significantly elevated on days 0 to 2 after onset of subarachnoid hemorrhage. Atrial natriuretic peptide concentrations remained high in patients who developed mild hyponatremia on days 6 to 14 after onset of subarachnoid hemorrhage. In contrast, antidiuretic hormone concentrations became significantly lower during the second week in these patients.<\/jats:p>\n          <jats:p>Mild hyponatremia after subarachnoid hemorrhage may be attributable not to the syndrome of inappropriate secretion of antidiuretic hormone but to cerebral salt-wasting syndrome. Atrial natriuretic peptide may be a causal natriuretic factor in cerebral salt-wasting syndrome.<\/jats:p>","DOI":"10.1161\/01.str.25.11.2198","type":"journal-article","created":{"date-parts":[[2011,6,17]],"date-time":"2011-06-17T20:08:03Z","timestamp":1308341283000},"page":"2198-2203","update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":103,"title":["Alterations in plasma concentrations of natriuretic peptides and antidiuretic hormone after subarachnoid hemorrhage."],"prefix":"10.1161","volume":"25","author":[{"given":"E","family":"Isotani","sequence":"first","affiliation":[{"name":"Department of Neurosurgery, School of Medicine, Tokyo Medical University, Japan."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R","family":"Suzuki","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, School of Medicine, Tokyo Medical University, Japan."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K","family":"Tomita","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, School of Medicine, Tokyo Medical University, Japan."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M","family":"Hokari","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, School of Medicine, Tokyo Medical University, Japan."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S","family":"Monma","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, School of Medicine, Tokyo Medical University, Japan."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F","family":"Marumo","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, School of Medicine, Tokyo Medical University, Japan."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K","family":"Hirakawa","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, School of Medicine, Tokyo Medical University, Japan."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","container-title":["Stroke"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ahajournals.org\/doi\/pdf\/10.1161\/01.STR.25.11.2198","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,12]],"date-time":"2024-05-12T22:26:36Z","timestamp":1715552796000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ahajournals.org\/doi\/10.1161\/01.STR.25.11.2198"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1994,11]]},"references-count":0,"journal-issue":{"issue":"11","published-print":{"date-parts":[[1994,11]]}},"alternative-id":["10.1161\/01.STR.25.11.2198"],"URL":"https:\/\/doi.org\/10.1161\/01.str.25.11.2198","relation":{},"ISSN":["0039-2499","1524-4628"],"issn-type":[{"value":"0039-2499","type":"print"},{"value":"1524-4628","type":"electronic"}],"subject":[],"published":{"date-parts":[[1994,11]]},"assertion":[{"value":"1994-11-01","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}